Alan L Rockwood

US Patent:

6992299, Jan 31, 2006

Filed:

Dec 18, 2003

Appl. No.:

10/739949

Inventors:

Edgar D. Lee - Highland UT, US
Milton L. Lee - Pleasant Grove UT, US
Alan L. Rockwood - Provo UT, US
Li Zhou - Provo UT, US

Assignee:

Brigham Young University - Provo UT

International Classification:

H01J 49/24

US Classification:

250396R, 250423, 250281, 250282, 250283, 250288

Abstract:

A method and apparatus for focusing ions for delivery to an ion detection device using an aerodynamic ion focusing system that uses a high-velocity converging gas flow at an entrance aperture to focus an ion plume by reducing spreading and increasing desolvation of ions, and wherein a voltage is applied to at least a portion of the aerodynamic ion focusing system to assist in the focusing and delivery of ions to the ion detection device.

US Patent:

7060987, Jun 13, 2006

Filed:

Mar 3, 2004

Appl. No.:

10/793689

Inventors:

Edgar D. Lee - Highland UT, US
Alan L. Rockwood - Provo UT, US
Bingfang Yue - Provo UT, US
Milton L. Lee - Pleasant Grove UT, US

Assignee:

Brigham Young University - Provo UT

International Classification:

H01J 27/00

US Classification:

250423R, 250282, 250287, 134 13, 134 1

Abstract:

A radio-frequency quadrupole ion guide having a symmetrical magnetic field disposed along an axis of the ion guide, wherein the system provides prolonged interaction between electrons and uncharged compounds within an ionization volume of the ion guide, resulting in enhanced ion creation.

US Patent:

7075064, Jul 11, 2006

Filed:

May 20, 2005

Appl. No.:

11/134560

Inventors:

James R. Oliphant - Pleasant Grove UT, US
H. Dennis Tolley - Mapleton UT, US
Alan Rockwood - Provo UT, US
Edgar Lee - Highland UT, US
Milton Lee - Pleasant Grove UT, US

Assignee:

Brigham Young University - Provo UT

International Classification:

H01J 49/26

US Classification:

250281, 250282, 702 26

Abstract:

A system and method are provided of extracting spectra from data produced by temporally indexed spectral scans from a spectrometer and spectrometer. The method includes the operation of receiving a data matrix from the spectrometer. The noise can then be removed from the data matrix. A further operation is identifying spectra of interest in the data matrix based on information content. In addition, a reduction transformation can be applied to the data matrix based upon the spectra of interest based upon the denizen transformation for the purpose of extracting the spectra of interest from the data matrix.

US Patent:

7075070, Jul 11, 2006

Filed:

Jun 21, 2004

Appl. No.:

10/873752

Inventors:

Edgar D. Lee - Highland UT, US
Alan L. Rockwood - Provo UT, US
Milton L. Lee - Pleasant Grove UT, US
Samuel E. Tolley - Springville UT, US

Assignee:

Brigham Young University - Provo UT

International Classification:

B01D 59/44
H01J 49/00

US Classification:

250294, 250281, 250282

Abstract:

A single set of electrodes, wherein different electrical potentials are applied to the single set of electrodes at different times in order to perform both ion mobility-based spectrometry and mass spectrometry (MS) on a sample of ions, wherein the ions are processed by performing ion mobility-based spectrometry and mass spectrometry in any sequence, any number of times, and as isolated or superposed procedures in order to trap, separate, fragment, and/or analyze charged particles and charged particles derived from atoms, molecules, particles, sub-atomic particles and ions.

US Patent:

7158903, Jan 2, 2007

Filed:

Mar 14, 2003

Appl. No.:

10/508068

Inventors:

Mark M. Kushnir - Salt Lake City UT, US
Alan L. Rockwood - Provo UT, US
Gordon J. Nelson - Sandy UT, US

Assignee:

University of Utah - Salt Lake City UT

International Classification:

G06F 19/00

US Classification:

702 86, 436 43, 73 102

Abstract:

The present invention provides methods for high throughput analysis of analytes in complex mixtures for unresolved chromatographic peaks including specific embodiment for summing intensities for each mass transition of interest over a selected chromatographic peak () to generate a signal corresponding to total intensity for each transition (). The intensities are deconvoluted into intensities of individual analytes (), based on branching ratios acquired from authentic standards, and a comparison to calibration curve is performed to obtain a quantitative concentration measurement of a particular analyte in a sample.

US Patent:

7199362, Apr 3, 2007

Filed:

Apr 9, 2004

Appl. No.:

10/821660

Inventors:

Alan L. Rockwood - Provo UT, US
Edgar D. Lee - Highland UT, US
Nosa Agbonkonkon - Provo UT, US
Milton L. Lee - Pleasant Grove UT, US

Assignee:

Brigham Young University - Salt Lake City UT

International Classification:

H01J 49/40

US Classification:

250286, 250287

Abstract:

A cross-flow ion mobility analyzer (CIMA) that includes a component of gas flow that opposes an electric field that is established within a channel, wherein ions are carried through the channel, wherein ions of a specific mobility are trapped by the opposing electric field and flow field within the channel and are detected when the ions reach the end of the channel, wherein a detector at the end of the channel sees a continuous stream of mobility-selected ions, and wherein different ions are selected by modifying the electric field and/or the velocity of the flow field.

US Patent:

7227138, Jun 5, 2007

Filed:

Jun 28, 2004

Appl. No.:

10/878989

Inventors:

Edgar D. Lee - Highland UT, US
Alan L. Rockwood - Provo UT, US
Randall Waite - Springville UT, US
Stephen A. Lammert - Glenburn ME, US
Milton L. Lee - Pleasant Grove UT, US

Assignee:

Brigham Young University - Provo UT

International Classification:

H01J 49/00

US Classification:

250292, 250288, 250291, 250290, 250283, 250282

Abstract:

A virtual ion trap that uses electric focusing fields instead of machined metal electrodes that normally surround the trapping volume, wherein two opposing surfaces include a plurality of uniquely designed and coated electrodes, and wherein the electrodes can be disposed on the two opposing surfaces using plating techniques that enable much higher tolerances to be met than existing machining techniques.

US Patent:

7375320, May 20, 2008

Filed:

May 24, 2007

Appl. No.:

11/805789

Inventors:

Edgar D. Lee - Highland UT, US
Alan L. Rockwood - Provo UT, US
Randall Waite - Springville UT, US
Stephen A. Lammert - Glenburn ME, US
Milton L. Lee - Pleasant Grove UT, US

Assignee:

Brigham Young University - Provo UT

International Classification:

H01J 49/00

US Classification:

250292, 250282, 250290, 250291, 250288, 250283

Abstract:

A virtual ion trap that uses electric focusing fields instead of machined metal electrodes that normally surround the trapping volume, wherein two opposing surfaces include a plurality of uniquely designed and coated electrodes, and wherein the electrodes can be disposed on the two opposing surfaces using plating techniques that enable much higher tolerances to be met than existing machining techniques.