Tom Yao Hsiang Wu - San Diego CA, US Yongkai Li - San Diego CA, US Alex Cortez - San Diego CA, US Kathy Yue - Riverside CA, US Xiaoyue Zhang - San Diego CA, US Manmohan Singh - Lexington MA, US David Skibinski - Siena, IT
The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.
Compounds And Compositions As Tlr Activity Modulators
Alex Cortez - San Diego CA, US Yongkai Li - San Diego CA, US Pranab Mishra - San Diego CA, US Manmohan Singh - Lexington MA, US David Skibinski - Siena, IT Nicholas Valiante - Cambridge MA, US Tom Yao-Hsiang Wu - San Diego CA, US Xiaoyue Zhang - San Diego CA, US Yefen Zou - San Diego CA, US
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: Xis N; Xis N Or CR; Xis —CR═CR.
Compounds And Compositions As Tlr Activity Modulators
TOM YAO-HSIANG WU - SAN DIEGO CA, US YONGKAI LI - SAN DIEGO CA, US ALEX CORTEZ - SAN DIEGO CA, US YEFEN ZOU - SAN DIEGO CA, US PRANAB MISHRA - SAN DIEGO CA, US XIAOYUE ZHANG - SAN DIEGO CA, US NICHOLAS VALIANTE - EMERYVILLE CA, US
International Classification:
C07D 471/04 C07D 471/14
US Classification:
514293, 514292
Abstract:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: Xis N; Xis N Or CR; Xis —CR═CR.
- Basel, CH Steven BENDER - Oceanside CA, US Alex Cortez - San Diego CA, US Sarah COX - San Diego CA, US Jonathan DEANE - San Diego CA, US Scott Martin GLASER - San Diego CA, US Ben WEN - Encinitas CA, US Tom Yao-Hsiang WU - San Diego CA, US
International Classification:
A61K 47/68 C07K 16/28 A61P 35/00
Abstract:
Provided herein are antibodies to DC-SIGN, conjugates of DC-SiGN antibodies, and DC-SiGN antibody fusion proteins and the use of such antibodies, conjugates, and fusion proteins for the treatment of diseases such as cancer.
Alex CORTEZ - San Diego CA, US Bernhard Hubert GEIERSTANGER - Solana Beach CA, US Timothy Z. HOFFMAN - San Diego CA, US Shailaja KASIBHATLA - San Diego CA, US Tetsuo UNO - San Diego CA, US Xing WANG - San Diego CA, US Tom Yao-Hsiang WU - San Diego CA, US
Provided herein are antibody conjugates comprising toll-like receptor agonists and the use of such conjugates for the treatment of cancer. In some embodiments, the conjugates comprise anti-HER2 antibodies.
Compounds And Compositions As Toll-Like Receptor 7 Agonists
Alex CORTEZ - San Diego CA, US Timothy HOFFMAN - San Diego CA, US Yongkai LI - Del Mar CA, US Tom Yao-Hsiang WU - San Diego CA, US Xiaoyue ZHANG - San Diego CA, US
Assignee:
NOVARTIS AG - Basel
International Classification:
C07D 487/04
Abstract:
The invention provides a compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat diseases or disorders associated with Toll-Like Receptor 7 activity.
Adsorption Of Immunopotentiators To Insoluble Metal Salts
- Rixensart, BE David A.G. SKIBINKSI - Singapore, SG Tom Yao-Hsiang WU - San Diego CA, US Yongkai LI - San Diego CA, US Alex CORTEZ - San Diego CA, US Xiaoyue ZHANG - San Diego CA, US Yefen ZOU - San Diego CA, US Timothy Z. HOFFMAN - San Diego CA, US Jianfeng PAN - San Diego CA, US Kathy YUE - Minneapolis MN, US
Immunopotentiators can be adsorbed to insoluble metal salts, such as aluminium salts, to modify their pharmacokinetics, pharmacodynamics, intramuscular retention time, and/or immunostimulatory effect. Immunopotentiators are modified to introduce a moiety, such as a phosphonate group, which can mediate adsorption. These modified compounds can retain or improve their in vivo immunological activity even when delivered in an adsorbed form.
Compounds And Compositions As Tlr Activity Modulators
Alex Cortez - San Diego CA, US Yongkai Li - Del Mar CA, US Manmohan Singh - Cary NC, US David Skibinski - Aspen Heights, SG Kathy Yue - Riverside CA, US Tom Yao-Hsiang Wu - San Diego CA, US Xiaoyue Zhang - San Diego CA, US
Assignee:
Novartis AG - Basel
International Classification:
C07F 9/6561
Abstract:
The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.
Name / Title
Company / Classification
Phones & Addresses
Alex Cortez
Chatsworth Collision Center Auto Body Repair · Auto Detailing · Auto Painting · Buffing & Polishing
10040 Canoga Ave, Chatsworth, CA 91311 (818)7340270
George Industries Valmont Inc East Los Angeles, CA Jul 2013 to Feb 2014 Racker / PackerFile Keepers LLC Montebello, CA Nov 2002 to Mar 2012 File Processor
Education:
Westwood College Los Angeles, CA 2015 to 2016 Bachelor in Criminal Justice AdministrationWestwood College Los Angeles, CA Jan 2015 Associates in Criminal Justice
Skills:
Bilingual, Fluent: English, Spanish California Guard Card Certified
May 2014 to 2000 Public Affairs InternOrange County District Attorney's Office - North Branch Fullerton, CA Feb 2012 to May 2014 Office TechnicianUnited States Department of Commerce, Bureau of the Census Placentia, CA Nov 2009 to Aug 2010 Recruiting and Administrative Clerk
Education:
California State University Fullerton, CA 2012 to 2015 Bachelor of Arts in CommunicationsSantiago Canyon College Orange, CA May 2011 Associate's in Liberal Arts
Youtube
Alex Cortez - Don't speak live @Dorian Gray V...
Alex Cortez is rocking the Club Dorian Gray Vienna.......wit... is ne...
Category:
Music
Uploaded:
14 Nov, 2008
Duration:
4m 59s
Taio Cruz - Dynamite (Alex Cortez vs. PitchBo...
www.myspace.com twitter.com www.youtube.com
Category:
Music
Uploaded:
17 Oct, 2010
Duration:
5m 17s
Dont speak - Alex Cortez
Pussylickerz Radio Edit
Category:
Music
Uploaded:
27 Nov, 2008
Duration:
4m 28s
Alex Cortez - Don't Speak (DJ Meiyo Remix)
Dj Meiyo Set Live Alex Cortez - Don't Speak Remix 2010 (Serb)
Category:
Music
Uploaded:
10 Jan, 2010
Duration:
3m 22s
Alec Cortez - Heart of a Champion
his is the recruiting video of one, Alec Cortez. If you don't know the...
Sun Terrace Elementary School Concord CA 1987-1990, Valle Verde Elementary School Walnut Creek CA 1990-1993, Sequoia Middle School Pleasant Hill CA 1993-1996
MusicCity Hollywood CAProgram Director / Music Director (Latin Rock Form... Past: Sales & Marketing at Radio & Records, A&R / Label Manager at Three Kings Records / Geffen...
Googleplus
Alex Cortez
Lived:
Alameda, CA Concord, CA Pleasant Hill, CA Martinez, CA San Francisco, CA
Education:
San Francisco State University - Philosophy
Relationship:
Engaged
About:
Cyclist and junk
Tagline:
Live life
Alex Cortez
Lived:
Los Angeles, CA
Work:
Law Office Of Nelson & Natale LLP - Marketing / New Media Director
Education:
USC Gould School of Law
Alex Cortez
Education:
Marston Middle School - Math
About:
HI my name is alex cortez Im beast at soccer Im single and i like messing with people
Tagline:
Add me up there ^^^^^^^^^^^^^^^^^^^^^^^^^^^ !!
Bragging Rights:
I survived middle school with a GPA of 3.6332 im single
Alex Cortez
Lived:
Long Beach,CA
Education:
Cabrillo High School
Bragging Rights:
Surviving High School
Alex Cortez
Education:
Los Angeles Valley College - Liberal Studies
Relationship:
Single
Bragging Rights:
Sponsor a 3 year old boy from Chile. Tutor first graders (for free!) What the fuck do you do for others?! "A little consideration, a little thought for others, makes all the difference.”
Alex Cortez
Education:
New Mexico State University - Music education
Alex Cortez
Work:
Cafe 47
Alex Cortez
About:
Just an ordinary guy from San Antonio, who's trying to find his place in this ever changing world we live in. My interests range far and wide, from music, to art, to philosophy and everything in ...