Alexander O Matschiner from 11840 Farmland Dr, Rockville, MD 20852, age 57, Phone: (301)2300078

Name / Title

Company / Classification

Phones & Addresses

Alexander Matschiner
Chief Operating Officer

BioFactura, Inc.
Biotechnology · Commercial Medical Research Srvcs

9430 Ky West Ave SUITE 125, Rockville, MD 20850
(301)3158002

Soluble And Membrane Anchored Forms Of Lassa Virus Subunit Proteins
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US Patent:

20100261640, Oct 14, 2010
Filed:

Apr 10, 2008
Appl. No.:

12/450756
Inventors:

Luis M. Branco - New Orleans LA, US
Alexander Matschiner - Rockville MD, US
Megan M. Illick - Gaithersburg MD, US
Darryl B. Sampey - Frederick MD, US
Robert F. Garry - New Orleans LA, US
Daniel G. Bausch - New Orleans LA, US
Joseph N. Fair - Knoxville MD, US
Mary C. Guttieri - Frederick MD, US
Kathleen A. Cashman - Purcellville VA, US
Russell B. Wilson - Mandeville LA, US
Peter C. Kulakosky - Metairie LA, US
F. Jon Geske - Commerce City CO, US
International Classification:

A61K 38/16
C07K 14/08
C07H 21/04
C12N 15/63
C07K 16/10
C12Q 1/70
C12P 21/02
A61P 31/14
US Classification:

514 37, 530395, 5303873, 536 2372, 4353201, 5303879, 435 5, 435 697
Abstract:

The invention discloses compositions comprising soluble and membrane-anchored forms of Lassa virus (LASV) glycoprotein 1 (GP1), glycoprotein 2 (GP2), the glycoprotein precursor (GPC), the nucleocapsid protein (NP), and the nucleic acids encoding these proteins. This invention further relates to diagnostic and preventative methods using these compositions. Preventative methods include preparation of vaccines, as well as factors (e.g. small molecules) that inhibit LASV infectivity. Further, the invention relates to diagnostic and therapeutic antibodies including neutralizing antibodies for the prevention and treatment of infection by LASV and other arenaviruses.

Soluble And Membrane-Anchored Forms Of Lassa Virus Subunit Proteins
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US Patent:

20140377740, Dec 25, 2014
Filed:

Jan 30, 2014
Appl. No.:

14/168438
Inventors:

- New Orleans LA, US
Alexander MATSCHINER - Rockville MD, US
Megan M. ILLICK - Gaithersburg MD, US
Darryl B. SAMPEY - Frederick MD, US
Robert F. GARRY - New Orleans LA, US
Daniel G. BAUSCH - New Orleans LA, US
Joseph N. FAIR - Knoxville MD, US
Mary C. GUTTIERI - Frederick MD, US
Kathleen A. CASHMAN - Purcellville VA, US
Russell B. WILSON - Mandeville LA, US
Peter C. KULAKOSKY - Metairie LA, US
F. Jon GESKE - Commerce City CO, US
Assignee:

BIOFACTURA, INC. - Rockville MD
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND - New Orleans LA
International Classification:

C07K 14/005
G01N 33/569
C07K 16/10
US Classification:

435 5, 530395, 5303873
Abstract:

Soluble and membrane-anchored forms of Lassa virus (LASV) glycoprotein 1 (GP1), glycoprotein 2 (GP2), the glycoprotein precursor (GPC), the nucleocapsid protein (NP), and the nucleic acids encoding these proteins are disclosed, as well as diagnostic and preventative methods using these compositions. Also disclosed are methods including preparation of vaccines, factors (e.g. small molecules) that inhibit LASV infectivity, and diagnostic and therapeutic antibodies including neutralizing antibodies for the prevention and treatment of infection by LASV and other arenaviruses.

Alexander O Matschiner