Alexander Rudolph Ochman from Bend, OR, age 44

Compounds And Methods For Treating Disorders Related To Glucose Metabolism
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US Patent:

20100004273, Jan 7, 2010
Filed:

Jul 1, 2009
Appl. No.:

12/495857
Inventors:

Andrew G. Reaume - Exton PA, US
Michael S. Saporito - Exton PA, US
Alexander R. Ochman - Exton PA, US
Christopher A. Lipinski - Waterford CT, US
Assignee:

MELIOR DISCOVERY, INC. - Exton PA
International Classification:

A61K 31/513
C07D 239/545
A61P 3/10
US Classification:

514274, 544314
Abstract:

The present invention relates to compounds and pharmaceutically acceptable salts thereof, and compositions comprising the same, that are useful in modulating lyn kinase activity, treating obesity, type II diabetes, metabolic syndrome, and in reducing blood glucose level, weight gain, or fat depot level, or treating a disease or condition associated with the same.

Methods Of Activating Irs-1 And Akt
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US Patent:

20100197710, Aug 5, 2010
Filed:

Jul 22, 2008
Appl. No.:

12/669574
Inventors:

Andrew G. Reaume - Exton PA, US
Michael S. Saporito - Exton PA, US
Alexander R. Ochman - Exton PA, US
Assignee:

MELIOR PHARMACEUTICALS I, INC. - Exton PA
International Classification:

A61K 31/513
A61P 3/10
A61P 3/04
A61P 9/12
A61P 13/12
A61P 15/10
A61P 3/06
US Classification:

514274
Abstract:

The present invention provides methods of activating IRS-1 and/or AKT and methods of treating or preventing IRS-1- and/or AKT-related disease, condition, or disorder.

Prevention Of Pancreatic Beta Cell Degeneration
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US Patent:

20130158055, Jun 20, 2013
Filed:

May 27, 2011
Appl. No.:

13/700191
Inventors:

Andrew G. Reaume - Exton PA, US
Michael S. Saporito - Exton PA, US
Alexander R. Ochman - Exton PA, US
International Classification:

A61K 31/513
US Classification:

514274
Abstract:

The present invention relates to compounds and pharmaceutically acceptable salts thereof and formulations comprising the compounds or a pharmaceutically acceptable salts thereof that are useful in methods of preventing pancreatic beta cell degeneration or methods of treating a disorder associated with pancreatic beta cell degeneration, such as type I diabetes.

Prevention Of Pancreatic Cell Degeneration
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US Patent:

20200215067, Jul 9, 2020
Filed:

Aug 21, 2019
Appl. No.:

16/546595
Inventors:

- Exton PA, US
Michael S. Saporito - Exton PA, US
Alexander R. Ochman - Exton PA, US
International Classification:

A61K 31/513
Abstract:

The present invention relates to compounds and pharmaceutically acceptable salts thereof and formulations comprising the compounds or a pharmaceutically acceptable salts thereof that are useful in methods of preventing pancreatic beta cell degeneration or methods of treating a disorder associated with pancreatic beta cell degeneration, such as type I diabetes.

Treatment Of Type I And Type Ii Diabetes
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US Patent:

20200215068, Jul 9, 2020
Filed:

Jan 8, 2020
Appl. No.:

16/737200
Inventors:

- Exton PA, US
Michael S. Saporito - Exton PA, US
Alexander R. Ochman - Exton PA, US
International Classification:

A61K 31/513
A61K 9/00
A61K 47/22
A61K 38/28
Abstract:

The present invention provides methods of treating Type I or Type II diabetes in a mammal by administering an effective amount of insulin and an effective amount of a phenoxypyrimidinone compound to the mammal in need of such treatment, and formulations for carrying out the methods.

Treatment Of Type I And Type Ii Diabetes
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US Patent:

20150190396, Jul 9, 2015
Filed:

Dec 12, 2012
Appl. No.:

14/364792
Inventors:

- Exton PA, US
Michael S. Saporito - Exton PA, US
Alexander R. Ochman - Exton PA, US
Assignee:

Melior Pharmaceuticals l, Inc. - Exton PA
International Classification:

A61K 31/513
A61K 9/00
A61K 38/28
Abstract:

The present invention provides methods of treating Type I or Type II diabetes in a mammal by administering an effective amount of insulin and an effective amount of a phenoxypyrimidinone compound to the mammal in need of such treatment, and formulations for carrying out the methods.

Alexander Rudolph Ochman