Alice A Cheng

US Patent:

20110262477, Oct 27, 2011

Filed:

Oct 6, 2009

Appl. No.:

13/122793

Inventors:

Alice Cheng - Chicago IL, US
Vilasack Thammavongsa - Chicago IL, US
Justin Kern - Mountain View CA, US
Dominique M. Missiakas - Chicago IL, US
Olaf Schneewind - Chicago IL, US

Assignee:

UNIVERSITY OF CHICAGO - Chicago IL

International Classification:

A61K 39/085
A61P 31/04
A61P 37/04
C07K 19/00

US Classification:

4241901, 4242431, 42419711, 530405, 4242001

Abstract:

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve an Eap, Emp and/or AdsA amino acid sequence, or an agent that binds and inhibits the same.

US Patent:

20120114686, May 10, 2012

Filed:

Apr 5, 2010

Appl. No.:

13/260878

Inventors:

Olaf Schneewind - Chicago IL, US
Alice Cheng - Chicago IL, US
Dominique M. Missiakas - Chicago IL, US
Hwan Keun Kim - Bolingbrook IL, US

Assignee:

UNIVERSITY OF CHICAGO - Chicago IL

International Classification:

A61K 39/085
A61P 31/04
A61P 37/04
C07K 14/31
C12P 21/00

US Classification:

4241901, 530324, 435 711, 4242431

Abstract:

Disclosed are methods and compositions for treating or preventing a bacterial infection using a non-toxigenic Protein A (SpA) variant.

US Patent:

20120282247, Nov 8, 2012

Filed:

May 7, 2012

Appl. No.:

13/465541

Inventors:

Olaf Schneewind - Chicago CA, US
Alice G. Cheng - Boston MA, US
Dominique M. Missiakas - Chicago IL, US
Hwan Keun Kim - Bolingbrook IL, US

International Classification:

A61K 39/085
C07K 14/31
A61K 39/395
A61P 31/04

US Classification:

4241301, 4242431, 530350

Abstract:

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve an Ebh antigen.

US Patent:

20130136746, May 30, 2013

Filed:

Apr 5, 2011

Appl. No.:

13/639465

Inventors:

Olaf Schneewind - Chicago IL, US
Alice Cheng - Chicago IL, US
Dominique M. Missiakas - Chicago IL, US
Hwan Keun Kim - Naperville IL, US

Assignee:

The University of Chicago - Chicago IL

International Classification:

A61K 39/40

US Classification:

4241391

Abstract:

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant or an antibody directed thereto.

US Patent:

20130230550, Sep 5, 2013

Filed:

Sep 9, 2011

Appl. No.:

13/821943

Inventors:

Olaf Schneewind - Chicago IL, US
Alice G. Cheng - Boston MA, US
Dominique M. Missiakas - Chicago IL, US
Hwan Keun Kim - Naperville IL, US
Hye-Young Kim - Rancho Cucamonga CA, US

Assignee:

The University of Chicago - Chicago IL

International Classification:

A61K 39/085

US Classification:

4241901, 4242431

Abstract:

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. In some embodiments, the methods and compositions involve SdrD, ClfA, and/or FnbpB polypeptides.

US Patent:

20210290748, Sep 23, 2021

Filed:

Jun 7, 2021

Appl. No.:

17/340532

Inventors:

- Chicago IL, US
Alice G. Cheng - Boston MA, US
Dominique M. Missiakas - Chicago IL, US
Hwan Keun Kim - Chicago IL, US

International Classification:

A61K 39/085
C07K 14/31
C07K 16/12
A61P 31/04
A61P 37/04

Abstract:

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a . The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.

US Patent:

20210093706, Apr 1, 2021

Filed:

Dec 7, 2020

Appl. No.:

17/247294

Inventors:

- Chicago IL, US
Andrea Dedent - Chicago IL, US
Alice Cheng - Chicago IL, US
Carla Emolo - Chicago IL, US
Dominique Missiakas - Chicago IL, US
Olaf Schneewind - Chicago IL, US

Assignee:

The University of Chicago - Chicago IL

International Classification:

A61K 39/085
A61K 38/48
C07K 14/31
C12N 9/52
A61K 45/06

Abstract:

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve coagulase Domains 1-2 and variants thereof.

US Patent:

20200140494, May 7, 2020

Filed:

Oct 23, 2019

Appl. No.:

16/661155

Inventors:

- Chicago IL, US
Alice G. Cheng - Boston MA, US
Dominique M. Missiakas - Chicago IL, US
Hwan Keun Kim - Chicago IL, US

International Classification:

C07K 14/31
C07K 16/12
A61K 39/085

Abstract:

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant.