Amy S Wong

US Patent:

20040102406, May 27, 2004

Filed:

Jun 12, 2003

Appl. No.:

10/312752

Inventors:

Pnina Brodt - Montreal, CA
John Nip - Brooklyn NY, US
Amy Wong - New York NY, US

International Classification:

A61K048/00
C07H021/04

US Classification:

514/044000, 536/023200

Abstract:

The present invention relates to a novel class of inhibitors of angiogenesis and/or metastasis that targets cell adhesion molecules, and more particularly to antisense phosphorothioate oligonucleotides directed to a subunit of an integrin vitronectin receptor to inhibit angiogenesis and/or metastasis. There is provided an antisense phosphorothioate oligonucleotide directed to one of a , and subunit of an integrin vitronectin receptor. The antisense phosphorothioate oligonucleotide blocks synthesis of the integrin vitronectin receptor on a target cell, thereby inhibiting angiogenesis and/or metastasis. There is provided a method for blocking angiogenesis and/or metastasis in a patient, comprising delivering an efficient amount of such an antisense phosphorothioate oligonucleotide to the target cell of the patient, thereby blocking synthesis of the integrin vitronectin receptor on the target cell and blocking angiogenesis and/or metastasis.

US Patent:

20060196215, Sep 7, 2006

Filed:

Dec 7, 2005

Appl. No.:

11/296681

Inventors:

Ethan Crumlin - Worcester MA, US
Geoff Becker - Philadelphia PA, US
Shauna Jin - Cambridge MA, US
Amy Wong - Brooklyn NY, US
Nathan Ball - Cambridge MA, US
Gabriel Sanchez - Stanford CA, US
Daniel Walker - Cambridge MA, US
Christopher Possinger - Boston MA, US
Muyiwa Oni - Boston MA, US
Emily Smith - Canton MI, US
Kabir Mukaddam - Boston MA, US
Myraida Vega Gonzalez - Lutherville Timonium MD, US

International Classification:

F25D 3/08

US Classification:

062371000, 062457200

Abstract:

A temperature regulating device capable for environmentally adaptable transport of transporting temperature sensitive products is provided including an insulated casing having an interior portion and a temperature regulating device for maintaining the interior portion at a temperature range lower than ambient temperature exterior to the interior portion, wherein the temperature regulating device maintains the lower temperature without external power sources. The temperature device is personally portable and includes a backpack attachment for transporting by a single individual.

US Patent:

20090139248, Jun 4, 2009

Filed:

Nov 24, 2008

Appl. No.:

12/277204

Inventors:

ETHAN J. CRUMLIN - Worchester MA, US
GEOFF BECKER - Philadelphia PA, US
SHAUNA JIN - Cambridge MA, US
AMY LAI WONG - Brooklyn NY, US
NATHAN BARKER BALL - Cambridge MA, US
GABRIEL NESTOR SANCHEZ - Stanford CA, US
DANIEL GEORGE WALKER - Cambridge MA, US
CHRISTOPHER PAUL POSSINGER - Boston MA, US
OLUMUYIWA ONI - Boston MA, US
EMILY SMITH - Canton MI, US
KABIR JAMES MUKADDAM - Boston MA, US
MYRAIDA A. VEGA GONZALEZ - Timonium MD, US

International Classification:

F25D 25/00
F25D 3/00
G01K 13/00
B65D 81/38

US Classification:

62 62, 62371, 624571, 62129, 22059227

Abstract:

Disclosed is a device for the transport of temperature sensitive products including an insulated container, an insulated lid, a fastener to secure the lid to the container, an active heat exchanger, a thermal circuit to circulate heat exchange, a temperature sensor read by a temperature regulating circuit that maintains a temperature range, a power source, and a support frame that arranges the elements of the device with the overall center of mass at a location adapted for transport and storage of the device. Disclosed is also a method of transport for temperature sensitive products including securing the temperature sensitive product within an insulated container with a lid, removing heat from the container to maintain a temperature range, strapping the device onto the user's back and adjusting to the shape of the user, freeing both hands during transport of the device, and minimizing hindrances to user mobility caused by the device.

US Patent:

52000290, Apr 6, 1993

Filed:

Dec 4, 1991

Appl. No.:

7/803290

Inventors:

Allan J. Bruce - Westfield NJ
Joseph Shmulovich - Murray Hill NJ
Amy Wong - Whitestone NY

Assignee:

AT&T Bell Laboratories - Murray Hill NJ

International Classification:

C03C 1500

US Classification:

156657

Abstract:

An active optical device comprises a glass, waveguiding structure disposed on a substantially planar principal surface of a substrate. The structure includes a silica-based, erbium-doped active core. The active core has an erbium-to-silicon atomic ratio of at least about 0. 01, an absolute erbium concentration of at least about 1. 4. times. 10. sup. 20 atoms per cubic centimeter, and a radiative lifetime of the erbium lasing level of at least about 7 milliseconds. Also disclosed is a method for forming an active optical device, including the step of depositing an erbium-doped active core by sputtering.