Andrew C Fischer

US Patent:

7829021, Nov 9, 2010

Filed:

Aug 15, 2007

Appl. No.:

11/839531

Inventors:

Timothy Hutchins - Attleboro Falls MA, US
Hal Watts - Holden MA, US
Steven Scampini - Groton MA, US
Eric Grimes - Hudson MA, US
Andrew H. Fischer - Stow MA, US

Assignee:

CYTYC Corporation - Marlborough MA

International Classification:

G01N 21/00

US Classification:

422 63, 422 64, 422 65, 422 66, 422 67, 422 99, 422100, 436174, 4352972, 4353081

Abstract:

A system for making cell blocks includes a cell block cassette and processing station, the cassette including a main body having a having a collection aperture formed therein and a filter assembly removably attached to the main body, the filter assembly defining a collection well in communication with the collection aperture, and having a filter positioned across a bottom surface of the collection well, the filter configured to retain cellular matter carried in a fluid that is dispensed into the collection well and flows across the filter. The cell block processor has a cassette interface removably seating the cell block cassette, and a sensor positioned or positionable to detect and monitor a fluid level in the collection well. The processing station includes an automated fluid delivery system operable to dispense a fluid into the collection well, and a controller operatively coupled to the fluid delivery system, wherein the controller causes the fluid delivery system to selectively dispense fluids into the collection well based at least in part on a flow rate across the filter determined at least in part based on changes in the monitored fluid level in the collection well.

US Patent:

7914462, Mar 29, 2011

Filed:

Aug 15, 2007

Appl. No.:

11/839528

Inventors:

Timothy Hutchins - Attleboro Falls MA, US
Hal Watts - Holden MA, US
Steven Scampini - Groton MA, US
Eric Grimes - Hudson MA, US
Andrew H. Fischer - Stow MA, US

Assignee:

Cytyc Corporation - Marlborough MA

International Classification:

A61B 10/10
B01L 3/02
C12M 1/00
G01N 1/30

US Classification:

600562, 7386416, 422 99, 435 405, 4353081

Abstract:

A system for making cell blocks includes a cell block cassette and processing station, the cassette including a main body having a having a collection aperture formed therein and a filter assembly removably attached to the main body, the filter assembly defining a collection well in communication with the collection aperture, and having a filter positioned across a bottom surface of the collection well, the filter configured to retain cellular matter carried in a fluid that is dispensed into the collection well and flows across the filter. The cell block processor has a cassette interface removably seating the cell block cassette, and a sensor positioned or positionable to detect and monitor a fluid level in the collection well. The processing station includes an automated fluid delivery system operable to dispense a fluid into the collection well, and a controller operatively coupled to the fluid delivery system, wherein the controller causes the fluid delivery system to selectively dispense fluids into the collection well based at least in part on a flow rate across the filter determined at least in part based on changes in the monitored fluid level in the collection well.

US Patent:

8088329, Jan 3, 2012

Filed:

Sep 7, 2010

Appl. No.:

12/876879

Inventors:

Timothy Hutchins - Attleboro Falls MA, US
Hal Watts - Holden MA, US
Steven A. Scampini - Groton MA, US
Eric Grimes - Hudson MA, US
Andrew H. Fischer - Stow MA, US

Assignee:

Cytyc Corporation - Marlborough MA

International Classification:

G01N 21/00

US Classification:

422 63, 422 64, 422 65, 422 66, 422 681, 422513, 422547, 436174, 436180

Abstract:

A system for making cell blocks includes a cell block cassette and processing station, the cassette including a main body having a having a collection aperture formed therein and a filter assembly removably attached to the main body, the filter assembly defining a collection well in communication with the collection aperture, and having a filter positioned across a bottom surface of the collection well, the filter configured to retain cellular matter carried in a fluid that is dispensed into the collection well and flows across the filter. The cell block processor has a cassette interface removably seating the cell block cassette, and a sensor positioned or positionable to detect and monitor a fluid level in the collection well. The processing station includes an automated fluid delivery system operable to dispense a fluid into the collection well, and a controller operatively coupled to the fluid delivery system, wherein the controller causes the fluid delivery system to selectively dispense fluids into the collection well based at least in part on a flow rate across the filter determined at least in part based on changes in the monitored fluid level in the collection well.

US Patent:

20060011415, Jan 19, 2006

Filed:

Apr 27, 2005

Appl. No.:

11/115629

Inventors:

Andrew Fischer - Littleton CO, US
Jason Koliscak - Mars PA, US
Richard Reynolds - Cranberry PA, US
Timothy Ecker - Arvada CO, US

International Classification:

A47L 3/04

US Classification:

182007000, 002455000

Abstract:

An integral rescue device preferably worn by a firefighter that includes a shock absorbing descender attached to the rescue device, a support line passing through the shock absorbing descender, an anchor connection attached to a first end of the support line in the vicinity of the shock absorbing descender, and an assembly for holding the support line. The assembly preferably includes a plurality of holders in which intermediate loops of the support line are retained near the terminus of each of the intermediate loops. In a preferred embodiment, the shock absorbing descender is attached to a waist belt of a self-contained breathing apparatus carrier with a support line passing through the shock absorbing descender, an anchor connection attached to a first end of the support line in the vicinity of the shock absorbing descender, and an assembly for holding the support line.

US Patent:

20210338856, Nov 4, 2021

Filed:

Jul 14, 2021

Appl. No.:

17/375737

Inventors:

- Abbott Park IL, US
Pathik Soni - Chicago IL, US
Lei Qiao - Addison TX, US
Dustin House - Carrollton TX, US
Lyle Yarnell - Richardson TX, US
Cathy Forsythe - Beach Park IL, US
Michael Shawn Murphy - Allen TX, US
Andrew Fischer - Euless TX, US
Akanksha Sharma - Ann Arbor MI, US
Joseph Esposito - Kenosha WI, US
Matt Effinger - Paddock Lake WI, US
Michael Futer - Grand Prairie TX, US

International Classification:

A61L 2/04
H05B 6/10
H05B 6/14
A61L 2/24
H05B 6/06
H05B 6/40

Abstract:

Inductive heating systems and method of controlling the same to reduce biological carryover are disclosed herein. An example system includes an induction heater including a tank circuit, the tank circuit including a work coil and a sense coil. The sense coil is to detect a magnetic field generated by the work coil and to output signals in response to the detection. The example system includes a controller to cause the tank circuit to oscillate at a resonant frequency in response to the signals and a power drive unit in communication with the controller and the induction heater. The power drive unit is to adjust power provided to the induction heater in response to the controller driving the tank circuit to oscillate at the resonant frequency.

US Patent:

20200256843, Aug 13, 2020

Filed:

May 1, 2020

Appl. No.:

16/864672

Inventors:

- Abbott Park IL, US
Mark A. Hayden - Ingleside IL, US
Peter J. Karabatsos - Glencoe IL, US
Andrew S. Schapals - Pleasant Prairie WI, US
Anthony S. Muerhoff - Kenosha WI, US
M. Felicia Bogdan - Gurnee IL, US
Thomas Leary - Kenosha WI, US
Sophie Laurenson - Basel-Land, CH
Andrew T. Fischer - Euless TX, US
Richard Haack - Skokie IL, US
Stefan Hershberger - Highland Park IL, US
Dustin House - Carrollton TX, US
Lei Qiao - Lake Bluff IL, US
M. Shawn Murphy - Allen TX, US
Mark R. Pope - Grayslake IL, US
QiaoQiao Ruan - Kildeer IL, US
Pathik Soni - Chicago IL, US
Sergey Tetin - Lindenhurst IL, US
Lyle Yarnell - Richardson TX, US

Assignee:

ABBOTT LABORATORIES - Abbott Park IL

International Classification:

G01N 33/487
G01N 33/53
B01L 3/00
G01N 33/543

Abstract:

Methods, devices, and systems for analyte analysis using a nanopore are disclosed. The methods, devices, and systems utilize a first and a second binding member that each specifically bind to an analyte in a biological sample. The method further includes detecting and/or counting a cleavable tag attached to the second binding member and correlating the presence and/or the number of tags to presence and/or concentration of the analyte. Certain aspects of the methods do not involve a tag, rather the second binding member may be directly detected/quantitated. The detecting and/or counting may be performed by translocating the tag/second binding member through a nanopore. Devices and systems that are programmed to carry out the disclosed methods are also provided.

US Patent:

20190153524, May 23, 2019

Filed:

Sep 14, 2017

Appl. No.:

16/312489

Inventors:

- Abbott Park IL, US
Jeffrey B. Huff - Lincolnshire IL, US
Sophie Laurenson - Allschwil, CH
Andrew Fischer - Euless TX, US
John Robinson - Gurnee IL, US

International Classification:

C12Q 1/6853

Abstract:

Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells. The detection modules disclosed here can be used for detecting analytes of interest which analytes may have been enriched by amplification, isolation, or other techniques.

US Patent:

20180193498, Jul 12, 2018

Filed:

Dec 21, 2017

Appl. No.:

15/851199

Inventors:

- Abbott Park IL, US
Pathik Soni - Chicago IL, US
Lei Qiao - Addison TX, US
Dustin House - Carrollton TX, US
Lyle Yarnell - Richardson TX, US
Cathy Forsythe - Beach Park IL, US
Michael Shawn Murphy - Allen TX, US
Andrew Fischer - Euless TX, US
Akanksha Sharma - Ann Arbor MI, US
Joseph Esposito - Kenosha WI, US
Matt Effinger - Paddock Lake WI, US
Michael Futer - Grand Prairie TX, US

International Classification:

A61L 2/04
H05B 6/06
H05B 6/10
H05B 6/40
A61L 2/24

Abstract:

Inductive heating systems and method of controlling the same to reduce biological carryover are disclosed herein. An example system includes an induction heater including a tank circuit. The example system includes a controller to drive the tank circuit to selectively oscillate at a resonant frequency for the tank circuit to inductively heat a work piece disposed proximate to the tank circuit.