Andrew W Goll

US Patent:

20160324998, Nov 10, 2016

Filed:

Jul 20, 2016

Appl. No.:

15/214853

Inventors:

- Elgin IL, US
Andrew W. Goll - Huntley IL, US
Jeffrey D. Stanley - Cary IL, US

International Classification:

A61L 2/20

Abstract:

A fill assembly sterilization system for a blow/fill/seal machine utilizes a closed loop circulation of sterilant containing gas. A typical sterilant is nitrogen dioxide. The closed loop includes a shroud that defines a plenum and encloses the fill system. Optionally, at least one high efficiency particulate absorption (HEPA) filter is provided in the closed loop. Sterility assurance level of 10can be achieved by subjecting the fill system to the sterilizing gas for at least 20 minutes at a temperature in the range of about 18 C. to about 30 C.