Andrew N Patterson

US Patent:

8476451, Jul 2, 2013

Filed:

Jul 21, 2008

Appl. No.:

12/669364

Inventors:

Jonathan A. Ellman - Oakland CA, US
Andrew W. Patterson - Oakland CA, US
Hillary Peltier - Jeanette PA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61K 31/426
A61K 31/427
C07D 277/30
A01N 43/78

US Classification:

548200, 548201, 514365

Abstract:

The present invention provides novel tubulysin analogues, methods of making and methods of using such analogues and conjugates thereof. The compounds of the invention are highly potent cell-growth inhibitors have been developed that are smaller and considerably more stable than tubulysin D.

US Patent:

20110263650, Oct 27, 2011

Filed:

Jul 21, 2008

Appl. No.:

12/669672

Inventors:

Jonathan A. Ellman - Berkeley CA, US
Andrew W. Patterson - Berkeley CA, US
Hillary Peltier - Berkeley CA, US
Florenz Sasse - Braunschweig, DE

Assignee:

HELMHOLTZ-ZENTRUM FÜR INFEKTIONS-FORSCHUNG GMBH - Braunschweig

International Classification:

A61K 31/454
A61P 17/06
A61K 31/426
A61P 35/00
C07D 401/12
C07D 277/587

US Classification:

514326, 546209, 548201, 514365

Abstract:

The present invention provides novel tubulysin analogues, methods of making and methods of using such analogues and conjugates thereof. The essential features for the potent cytotoxicity of tubulysin D have been established for the first time by the synthesis and evaluation of a series of analogues. By identifying functionality that surprisingly is not necessary for activity, highly potent cell-growth inhibitors have been developed that are smaller and considerably more stable than tubulysin D.

US Patent:

20140207499, Jul 24, 2014

Filed:

Jan 24, 2014

Appl. No.:

14/164034

Inventors:

- Mountain View CA, US
Brad Gerstner - Boston MA, US
Calvin Yang - Foster City CA, US
Roger Wong - Mountain VIew CA, US
Anthony H. Maggio - San Francisco CA, US
Brian McManus - San Francisco CA, US
Andrew Patterson - San Francisco CA, US

Assignee:

Room 77, Inc. - Mountain View CA

International Classification:

G06Q 50/12
G06Q 10/02

US Classification:

705 5

Abstract:

Techniques for allowing prospective hotel guests to check-in online are provided. An online check-in service sends, to a computing device of a prospective guest, an electronic notification that indicates that the prospective user can check-in online instead of having to wait in line at the hotel. A series of pages are presented to the prospective guest, such as a page to allow the prospective guest to specify room preferences and other requests, a page to allow the prospective guest to accept an upgrade offer, a page to confirm payment, and/or a page that shows a room assignment. In this way, a guest does not have to wait in a hotel lobby to be assigned a room. Also, a hotel may be notified when a confirmed guest is approaching the hotel to allow hotel staff to make any arrangements necessary to expedite the process of getting the guest to his/her room.