Andrew D Price

US Patent:

8526884, Sep 3, 2013

Filed:

Aug 19, 2011

Appl. No.:

13/214052

Inventors:

Andrew D. Price - Santa Clara CA, US
Varada Gopalakrishnan - Cupertino CA, US
Robert D. Lau - Dublin CA, US

Assignee:

Amazon Technologies, Inc. - Reno NV

International Classification:

H04B 7/00

US Classification:

455 412, 455419, 455420, 4555531

Abstract:

Computing devices can utilize various low power wakeup transceivers in order to control functional states of various components of those devices. Each transceiver can broadcast a beacon including appropriate information, which can be received by any other device with a transceiver that is within a propagation range of the beacon. A transceiver receiving the beacon can cause the received beacon to be analyzed by appropriate decision logic, which can determine any appropriate functionality to be activated or otherwise contacted in response to the beacon. In at least some embodiments, the beacon can cause another type of communication channel to be activated to establish communications with a device from which the beacon was received. In this way, the communications channel can be established without having to leave the channel active or manually activate that channel.

US Patent:

20220364150, Nov 17, 2022

Filed:

Jul 11, 2022

Appl. No.:

17/861503

Inventors:

- Pleasanton CA, US
Shalini GOHIL - Castro Valley CA, US
Christopher HINDSON - Livermore CA, US
Adam LOWE - Mountain House CA, US
Andrew D. PRICE - Hayward CA, US
Joseph Francis SHUGA - Pleasanton CA, US

Assignee:

10x Genomics, Inc. - Pleasanton CA

International Classification:

C12Q 1/6806
B01J 13/18
B01J 13/00
C08J 3/075

Abstract:

The present disclosure provides systems and methods for making a hydrogel comprising a cell, cell nucleus, or one or more components derived from a cell or cell nucleus. A method for making a hydrogel may comprise providing a cell or cell nucleus, a first polymer, wherein the first polymer comprises a plurality of first crosslink precursors, each of the plurality of first crosslink precursors comprising an azide group; providing a second polymer, wherein the second polymer comprises a plurality of second crosslink precursors, each of the plurality of second crosslink precursors comprising an alkyne group; and crosslinking the first polymer and the second polymer via a reaction between a first section of the first crosslink precursors and a second section of the second crosslink precursors, thereby providing the hydrogel comprising the cell or cell nucleus.

US Patent:

20220314187, Oct 6, 2022

Filed:

Dec 29, 2021

Appl. No.:

17/565038

Inventors:

- Pleasanton CA, US
Andrew D. PRICE - San Diego CA, US

International Classification:

B01J 19/00
C12Q 1/6834

Abstract:

Provided in some aspects are methods for light-controlled in situ surface patterning of an array. Compositions such as nucleic acid arrays produced by the methods are also disclosed.

US Patent:

20220276229, Sep 1, 2022

Filed:

Feb 24, 2022

Appl. No.:

17/680209

Inventors:

- Pleasanton CA, US
Eswar Prasad Ramachandran Iyer - Sunnyvale CA, US
Andrew Kohlway - Pleasanton CA, US
Luigi Jhon Alvarado Martinez - Walnut Creek CA, US
Katherine Pfeiffer - Oakland CA, US
Andrew D. Price - Hayward CA, US

International Classification:

G01N 33/532
C07K 14/74
C12N 15/85
G01N 33/543
G01N 33/548
C12N 15/10
C12Q 1/6804
C12Q 1/6806
G01N 33/50
G01N 33/53
G01N 33/58
C12Q 1/6818
C12Q 1/6827
C12Q 1/6881
C12N 15/11
G01N 33/569

Abstract:

The present disclosure provides methods of processing or analyzing a sample. A method for processing a sample may comprise hybridizing a probe molecule to a target region of a nucleic acid molecule (e.g., a ribonucleic acid (RNA) molecule), barcoding the probe-nucleic acid molecule complex, and performing extension, denaturation, and amplification processes. A method for processing a sample may comprise hybridizing first and second probes to adjacent or non-adjacent target regions of a nucleic acid molecule (e.g., an RNA molecule), linking the first and second probes to provide a probe-linked nucleic acid molecule, and barcoding the probe-linked nucleic acid molecule. One or more processes of the methods described herein may be performed within a partition, such as a droplet or well. One or more processes of the methods described herein may be performed on a cell, such as a permeabilized cell.

US Patent:

20220268795, Aug 25, 2022

Filed:

May 12, 2022

Appl. No.:

17/742793

Inventors:

- Pleasanton CA, US
Bryan C. STEWART - Pleasanton CA, US
Alexander Post KINDWALL - Pleasanton CA, US
Andrew PRICE - Pleasanton CA, US
John Richard CHEVILLET - Pleasanton CA, US

International Classification:

G01N 35/00
G01N 35/10

Abstract:

A calibration device is disclosed. The device comprises an array of teaching pendants. The device comprises a translation actuator configured to translate the array of teaching pendants to a set of x and y positions, wherein the x and y positions are measured in a plane substantially parallel to a floor of an instrument deck. The device comprises a plurality of height actuators configured to move each of the teaching pendants in a direction substantially perpendicular to the plane. One or more of the teaching pendants contact one or more teaching objects of an array of teaching objects above the instrument deck as a result of a position of the array of teaching pendants.

US Patent:

20220228201, Jul 21, 2022

Filed:

Dec 29, 2021

Appl. No.:

17/565028

Inventors:

- Pleasanton CA, US
David Michael PATTERSON - Oakland CA, US
Andrew D. PRICE - San Diego CA, US
Eswar Prasad RAMACHANDRAN IYER - Sunnyvale CA, US

International Classification:

C12Q 1/6837
C12Q 1/6869

Abstract:

Provided in some aspects are methods for light-controlled in situ surface patterning of a substrate. Compositions such as nucleic acid arrays produced by the methods are also disclosed. In some embodiments, provided herein is photocontrollable hybridization, where oligonucleotides with photo-caged bases prevent hybridization of complementary nucleic acid strands. Uncaging of the oligonucleotides allows hybridization and/or ligation of nucleic acid molecules at the exposed area. A large diversity of barcodes can be created in molecules on the substrate via sequential rounds of light exposure, hybridization, and ligation.

US Patent:

20220195420, Jun 23, 2022

Filed:

Nov 2, 2021

Appl. No.:

17/517282

Inventors:

- Pleasanton CA, US
Rajiv Bharadwaj - Pleasanton CA, US
Christopher Hindson - Pleasanton CA, US
Bill Kengli Lin - Pleasanton CA, US
Anthony Makarewicz - Livermore CA, US
Pranav Patel - Fremont CA, US
Katherine Pfeiffer - Berkeley CA, US
Andrew D. Price - Hayward CA, US
Tobias Daniel Wheeler - Alameda CA, US
Yifeng Yin - Elk Grove CA, US

International Classification:

C12N 15/10
C12Q 1/6806
C12Q 1/6869

Abstract:

Methods and systems are provided for sample preparation techniques and sequencing of macromolecular constituents of cells and other biological materials.

US Patent:

20230063675, Mar 2, 2023

Filed:

Oct 31, 2022

Appl. No.:

17/978130

Inventors:

- San Diego CA, US
Tarun Kumar Khurana - Fremont CA, US
Liangliang Qiang - San Diego CA, US
Andrew J. Price - San Mateo CA, US
Elisabet Rosas - El Cerrito CA, US

International Classification:

C12Q 1/6874
C12N 15/10

Abstract:

An example of a sequencing kit includes a flow cell and an encapsulation matrix precursor composition. The flow cell includes a plurality of chambers and primers attached within each of the plurality of chambers. The encapsulation matrix precursor composition consists of a fluid and a polymer selected from the group consisting of agar, agarose, alginate, heparin, alginate sulfate, dextran sulfate, hyaluronan, pectin, carrageenan, gelatin, chitosan, cellulose, a collagen polymer, and combinations thereof.