Andrew Stuart Thompson

US Patent:

6369247, Apr 9, 2002

Filed:

Sep 30, 1996

Appl. No.:

08/718408

Inventors:

Ross A. Miller - Fanwood NJ
Andrew S. Thompson - Mountainside NJ
Raman K. Bakshi - Edison NJ
Edward G. Corley - Old Bridge NJ

Assignee:

Merck Co., Inc. - Rahway NJ

International Classification:

C07J 900

US Classification:

552542, 552636, 540 2, 540106

Abstract:

The instant invention involves a process for oxidizing compounds containing an allylic group, i. e. those containing an allylic hydrogen or allylic alcohol group, to the corresponding enones, using a ruthenium-based catalyst in the presence of a hydroperoxide. Particularly, -5-steroidal alkenes can be oxidized to the corresponding -5-7-keto alkenes.

US Patent:

7737306, Jun 15, 2010

Filed:

Oct 22, 2008

Appl. No.:

12/255951

Inventors:

Andrew Thompson - Mountainside NJ, US
Shawn Zhang - Stirling NJ, US
Lonnie Robarge - Seattle WA, US

Assignee:

Suterra, LLC - Los Angeles CA

International Classification:

C07C 45/00

US Classification:

568486, 568488

Abstract:

One or more embodiments of the invention are directed to the synthetic methods for making lepidopteran pheromones including navel orangeworm pheromones. The synthetic methods involve novel, efficient, and environmentally benign steps and procedures.

US Patent:

8115035, Feb 14, 2012

Filed:

Apr 20, 2010

Appl. No.:

12/763589

Inventors:

Andrew Thompson - Mountainside NJ, US
Xiongzhi Zhang - Stirling NJ, US
Lonnie Robarge - Seattle WA, US

Assignee:

Suterra, LLC - Los Angeles CA

International Classification:

C07C 45/00

US Classification:

568486, 568488

Abstract:

One or more embodiments of the invention are directed to the synthetic methods for making lepidopteran pheromones including navel orangeworm pheromones. The synthetic methods involve novel, efficient, and environmentally benign steps and procedures.

US Patent:

8329957, Dec 11, 2012

Filed:

Feb 13, 2012

Appl. No.:

13/372288

Inventors:

Andrew Thompson - Mountainside NJ, US
Xiongzhi Zhang - Stirling NJ, US
Lonnie Robarge - Seattle WA, US

Assignee:

Suterra LLC - Los Angeles CA

International Classification:

C07C 45/00

US Classification:

568486, 568488

Abstract:

One or more embodiments of the invention are directed to the synthetic methods for making lepidopteran pheromones including navel orangeworm pheromones. The synthetic methods involve novel, efficient, and environmentally benign steps and procedures.

US Patent:

20130101534, Apr 25, 2013

Filed:

Dec 13, 2012

Appl. No.:

13/714136

Inventors:

ELIZABETH ARDEN, INC. - New York NY, US
Birgit Neudecker - Fuldatat-Rothwesten, DE
Eberhard Wieland - Goettingen, DE
Joseph C. DiNardo - Vesuvius VA, US
Andrew S. Thompson - Mountainside NJ, US
James Alan Kerschen - Somerset NJ, US
Peter C. Wade - Somerset NJ, US

Assignee:

ELIZABETH ARDEN, INC. - New York NY

International Classification:

C07C 69/95
A61K 8/37
A61K 8/97
A61Q 90/00
A61Q 19/00
A61K 8/67
A61Q 17/04
A61Q 19/10

US Classification:

424 60, 514533

Abstract:

The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted derivatives, methods of treating skin changes by topical application of these carboxylic acid-substituted idebenone derivatives, and their methods of synthesis. The carboxylic acid-substituted idebenone derivatives of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the carboxylic acid-substituted idebenone derivatives of the present invention have an antioxidant effect that is useful in treating a skin change.

US Patent:

20130190507, Jul 25, 2013

Filed:

Mar 5, 2013

Appl. No.:

13/785504

Inventors:

Rajendra Parasmal JAIN - Wakad, IN
Remy ANGELAUD - Union NJ, US
Andrew Thompson - Mountainside NJ, US
Carol LAMBERSON - Ringoes NJ, US
Scott GREENFIELD - Delmar NY, US

International Classification:

C07D 233/86
C07D 235/02

US Classification:

5483014, 5483211

Abstract:

Processes are provided for the synthesis of diarylthiohydantoin and diarylhydantoin compounds. Medicinal products containing the same find particular use in treating prostate cancer, including castration-resistant prostate cancer and/or hormone-sensitive prostate cancer.

US Patent:

50990330, Mar 24, 1992

Filed:

Jun 29, 1990

Appl. No.:

7/546487

Inventors:

Ichiro Shinkai - Westfield NJ
Andrew S. Thompson - Mountainside NJ
Thomas R. Verhoeven - Watchung NJ

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

C07D30702
C07D49800

US Classification:

549218

Abstract:

The present invention is directed to a process of making tetrahydrofuran of the formula (D) ##STR1## resulting in 2,5-diaryltetrahydrofuran PAF antagonists of pharmaceutically acceptable purity.

US Patent:

48661864, Sep 12, 1989

Filed:

Jun 30, 1988

Appl. No.:

7/213870

Inventors:

Andrew S. Thompson - Mountainside NJ
Thomas R. Verhoeven - Cranford NJ
Ichiro Shinkai - Westfield NJ

Assignee:

Merck & Co., Inc. - Rahway NJ

International Classification:

C07D30930

US Classification:

549292

Abstract:

A process and intermediates in preparation of 6-exomethylene derivatives of lovastatin and 8-acyl and di- and tetrahydro analogs thereof is disclosed.