Ryan B. Prince - Woodbury MN, US David S. Hays - Woodbury MN, US Angela K. Dillow - Minneapolis MN, US Randall P. Brown - White Bear Township MN, US G. Marco Bommarito - Stillwater MN, US John L. Battiste - Northfield MN, US
Colorimetric sensors comprising a receptor incorporated within polydiacetylene assemblies to form a transducer capable of indicating a color change when contacted with an analyte are disclosed. Methods of using the colorimetric sensor and a kit for the colorimetric detection of an analyte are also disclosed.
Colorimetric Sensors Constructed Of Diacetylene Materials
Ryan Prince - Woodbury MN, US David Hays - woodbury MN, US Angela dillow - Minneapolis MN, US G. Bommarito - Stillwater MN, US John Battiste - Northfield MN, US
Assignee:
3M Innovative Properties Company
International Classification:
G01N033/543 C08G063/91
US Classification:
436/518000, 525/054100
Abstract:
Colorimetric sensors comprising a receptor incorporated within polydiacetylene assemblies to form a transducer capable of indicating a color change when contacted with an analyte are disclosed. Methods of using the colorimetric sensor and a kit for the colorimetric detection of an analyte are also disclosed.
Angela K. Dillow - Minneapolis MN Robert S. Langer - Newton MA Neil Foster - Ortarmon, AU Jeffrey S. Hrkach - Somerville MA
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61L 200
US Classification:
422 28
Abstract:
A method is provided for sterilizing materials, particularly polymers, for drug delivery and implantation, wherein the material is treated with supercritical fluid carbon dioxide at pressures in the range of 2000 to 3000 psi (140 to 210 bar) and temperatures preferably between 30 and 45. degree. C. for periods between 20 minutes and six hours, more preferably between 0. 5 and 2 hours. Agitation, pressure cycling, and the presence of water were found to enhance the sterilization method, which promotes diffusion of the supercritical fluid carbon dioxide into the cells of the microorganism to thereby alter the pH within the cells, killing them. The magnitude and frequency of the pressure cycling, as well as the process time and temperature, may vary according to the type and form of the material to be sterilized and the type of organisms to be killed.
Brinda Lakshmi - Woodbury MN, US Angela Dillow - Minneapolis MN, US M. Free - St. Paul MN, US John Huizinga - Dellwood MN, US Patrick Mach - Shorewood MN, US Dasaratha Sridhar - Woodbury MN, US
International Classification:
C12Q 1/04
US Classification:
435034000
Abstract:
The invention relates to methods of detecting staphylococcus.
Isbn (Books And Publications)
Biomimetic Materials and Design: Biointerfacial Strategies, Tissue Engineering, and Targeted Drug Delivery