John J. Foster - Woodbury MN, US Angela S. Strantz - Mahtomedi MN, US
Assignee:
CNS THERAPEUTICS, INC. - Woodbury MN
International Classification:
A61K 31/195 A61P 21/02
US Classification:
514567
Abstract:
The present invention relates generally to a sterile, particulate-free, stable intrathecal baclofen solution with less than 0.5% 4-(4-chlorophenyl)-2-pyrrolidone, a degradation product. These solutions are stable under a variety of storage conditions and for extended periods of time. Also disclosed are methods for preparing such compositions.
Intrathecal Baclofen Pharmaceutical Dosage Forms And Related Delivery System
According to the subject invention, there is disclosed, a dosage and packaging configuration which includes the use of color-coded pre-filled syringes and vials to fill and refill infusion systems with existing and new dosage forms of intrathecal baclofen.
Intrathecal Baclofen Pharmaceutical Dosage Forms With Fewer Degradation Products
- Hazelwood MO, US Angela A. Strantz - Mahtomedi MN, US
International Classification:
A61K 31/197
US Classification:
514567
Abstract:
The present invention relates generally to a sterile, particulate-free, stable intrathecal baclofen solution with less than 0.5% of 4-(4-chlorophenyl)-2-pyrrolidone, a degradation product. These solutions are stable under a variety of storage conditions and for extended periods of time. Also disclosed are methods for preparing such compositions.
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