Edcon Chang - San Diego CA, US Tracy Duong - San Diego CA, US Takehiro Hirano - Osaka, JP Matthew H. McNiell - San Diego CA, US Yoshito Terao - Osaka, JP Angie Vassar - San Diego CA, US
Assignee:
Takeda Pharmaceutical Company Limited - Osaka
International Classification:
A01N 43/90 A61K 31/519
US Classification:
5142593, 544281
Abstract:
The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”). inhibiting compounds of the formula.
Edcon Chang - San Diego CA, US Tracy Duong - San Diego CA, US Angie Vassar - San Diego CA, US
Assignee:
Takeda Pharmaceutical Company Limited - Osaka
International Classification:
A61K 31/438 C07D 471/10
US Classification:
514278, 546 20
Abstract:
The present invention relates to acetyl coenzyme-A carboxylase (“ACC”) inhibiting compounds of the formulawherein the variables are as defined herein. In particular, the present invention relates to ACC1 and/or ACC2 inhibitors, compositions of matter, kits and articles of manufacture comprising these compounds, methods for inhibiting ACC1 and/or ACC2, and methods of making the inhibitors.
TAKEDA PHARMACEUTICAL COMPANY LIMITE LIMITED - SAN DIEGO CA, US MATTHEW H. MCNEILL - SAN DIEGO CA, US TRACY DUONG - SAN DIEGO CA, US ANGIE VASSAR - SAN DIEGO CA, US TAKEHIRO HIRANO - OSAKA, JP YOSHITO TERAO - OSAKA, JP
Assignee:
TAKEDA PHARMACEUTICAL COMPANY LIMITED - SAN DIEGO CA
The present invention relates to apoptosis signal-regulating kinase 1 (“ASK1”) inhibiting compounds of the formulawherein the variables are as defined herein. The invention also relates to pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.