Scott D. Edmondson - New York NY, US Emma Parmee - Scotch Plains NJ, US Ann E. Weber - Scotch Plains NJ, US Jinyou Xu - Scotch Plains NJ, US
Assignee:
Merck & Co., Inc - Rahway NJ
International Classification:
A61K 31/40 C07D 207/00
US Classification:
514423, 548537
Abstract:
Compounds having Formula I, including pharmaceutically acceptable salts and prodrugs thereof: (Formula I) are inhibitors of the dipep tidyl peptidase-IV enzyme (DP-IV), and are useful in the treatment of DP-IV mediated diseases and conditions, such as non-insulin dependent diabetes mellitus.
Dipeptidyl Peptidase Inhibitors For The Treatment Of Diabetes
Compounds having Formula I, including pharmaceutically acceptable salts and prodrugs thereof: (I) are inhibitors of the dipeptidyl peptidase-IV enzyme (DP-IV), and are useful in the treatment of DP-IV mediated diseases and conditions, such as non-insulin dependent diabetes mellitus.
Β-Amino Heterocyclic Dipeptidyl Peptidase Inhibitors For The Treatment Or Prevention Of Diabetes
Linda L. Brockunier - Orange NJ, US Joseph L. Duffy - Cranford NJ, US Dooseop Kim - Westfield NJ, US Emma R. Parmee - Scotch Plains NJ, US Ann E. Weber - Scotch Plains NJ, US
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07D 487/00 A01N 43/36
US Classification:
544236, 514249
Abstract:
The present invention is directed to compounds of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Phenylalanine Derivatives As Dipeptidyl Peptidase Inhibitors For The Treatment Or Prevention Of Diabetes
The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Cyclohexylalanine Derivatives As Dipeptidyl Peptidase-Iv Inhibitors For The Treatment Or Prevention Of Diabetes
The present invention is directed to novel cyclohexylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Beta-Amino Heterocyclic Dipeptidyl Peptidase Inhibitors For The Treatment Of Type 2 Diabetes
Scott D. Edmondson - Clark NJ, US Michael Fisher - Rahway NJ, US Dooseop Kim - Westfield NJ, US Malcolm MacCoss - Seabrook Island SC, US Emma R. Parmee - Scotch Plains NJ, US Ann E. Weber - Scotch Plains NJ, US Jinyou Xu - Scotch Plains NJ, US
Assignee:
Merck Sharp & Dohme Corp - Rahway NJ
International Classification:
A61K 31/495 A61K 31/40
US Classification:
514249, 514422, 514423, 514866
Abstract:
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
3-Amino-4-Phenylbutanoic Acid Derivatives As Dipeptidyl Peptidase Inhibitors For The Treatment Or Prevention Of Diabetes
Joseph Duffy - Cranford NJ, US Scott Edmondson - New York NY, US Dooseop Kim - Westfield NJ, US Brian Kirk - Basking Ridge NJ, US Liping Wang - Dayton NJ, US Ann Weber - Scotch Plains NJ, US
International Classification:
A61K 31/498 C07D 487/02
US Classification:
514249000, 544350000
Abstract:
The present invention is directed to 3-amino-4-phenylbutanoic acid derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Beta-Amino Heterocyclic Dipeptidyl Peptidase Inhibitors For The Treatment Or Prevention Of Diabetes
Scott Edmondson - New York NY, US Michael Fisher - Ringoes NJ, US Dooseop Kim - Westfield NJ, US Malcolm Maccoss - Freehold NJ, US Emma Parmee - Scotch Plains NJ, US Ann Weber - Scotch Plains NJ, US Jinyou Xu - Scotch Plains NJ, US
International Classification:
A61K 31/498 C07D 487/04
US Classification:
514249000, 544350000
Abstract:
The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Dimensions in Sound & The Studio Orchestra, Inc. - Madison, WI since Jan 1994
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Gerry and Ann Weber were recognized by the Dog Obedience Committee, chaired by Frank Mams, for their many years of volunteer service directing the eight-week dog training school held each spring at Camp Pioneer. The High Riders 4-H club presented certificates to Claire St. Peter, Erica Janes and Lis
Ann Weber, chief medical officer at NFRMC, said the hospital has a timeline of implementations required under the Affordable Care Act that is around 4 feet long. But Weber said many of the requirements have already been implemented.
Date: Oct 01, 2012
Category: Health
Source: Google
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San Francisco, CAPrincipal at Whiteshirt Design Past: Creative Director at LeapFrog, Creative Director at Ubisoft Entertainment A Creative Director and Designer with extensive experience delivering strategic, integrated brand campaigns from concept to execution. Professional and cool... A Creative Director and Designer with extensive experience delivering strategic, integrated brand campaigns from concept to execution. Professional and cool under fire, with a broad range of creative, management and technical skills.
An early adopter with a passion for design, music and film, my...
Saint Francis of Assisi School Los Angeles CA 1949-1953, Micheltorena Elementary School Los Angeles CA 1953-1953, Thomas Starr King Junior High School Los Angeles CA 1954-1956
Community:
Anthony Tony, Victor Ornelas
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Life
Retired from Pacific Bell in 1996, was a customer service rep for over 20 years...