- Zug, CH Ewelina MORAWA - Cambridge MA, US Jason SAGERT - Cambridge MA, US Annie Yang WEAVER - Cambridge MA, US
International Classification:
A61K 35/17 A61K 45/06 A61P 35/00 C07K 16/28
Abstract:
Combined therapy for treating multiple myeloma (MM), comprising (a) a population of genetically engineered T cells, which may express a chimeric antigen receptor (CAR) that binds B-cell maturation antigen (BCMA), and (b) an anti-CD38 antibody such as daratumumab or lenalidomide or a derivative thereof.
Activatable Anti-Cd166 Antibodies And Methods Of Use Thereof
- South San Francisco CA, US Rachel HUMPHREY - Princeton NJ, US W. Michael KAVANAUGH - Orinda CA, US Jonathan TERRETT - Lexington MA, US Annie Yang WEAVER - San Mateo CA, US Matthias WILL - San Francisco CA, US
International Classification:
A61K 47/68 C07K 16/28 A61K 47/65 A61P 35/00
Abstract:
Provided herein are activatable antibodies that specifically bind to CD166 and conjugated activatable antibodies that specifically bind to CD166. Also provided are methods of making and using these activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
Anti-Cd166 Antibodies, Activatable Anti-Cd166 Antibodies, And Methods Of Use Thereof
- South San Francisco CA, US Jason Gary Sagert - San Mateo CA, US Jonathan Alexander Terrett - Lexington MS, US Annie Yang Weaver - San Mateo CA, US Luc Roland Desnoyers - San Francisco CA, US Shweta Singh - Fremont CA, US
International Classification:
C07K 16/28 A61K 47/68 A61K 31/537
Abstract:
The invention relates generally to antibodies that bind CD166, activatable antibodies that specifically bind to CD166 and methods of making and using these anti-CD166 antibodies and anti-CD166 activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
Anti-Itga3 Antibodies, Activatable Anti-Itga3 Antibodies, And Methods Of Use Thereof
- South San Francisco CA, US Jonathan Alexander Terrett - Cupertino CA, US Luc Roland Desnoyers - San Francisco CA, US Shweta Singh - Fremont CA, US Annie Yang Weaver - San Mateo CA, US
International Classification:
C07K 16/28 C07K 7/08 A61K 47/68 C07K 16/30
Abstract:
The invention relates generally to antibodies that bind ITGa3, activatable antibodies that specifically bind to ITGa3 and methods of making and using these anti-ITGa3 antibodies and anti-ITGa3 activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
Anti-Cd71 Antibodies, Activatable Anti-Cd71 Antibodies, And Methods Of Use Thereof
- South San Francisco CA, US Kimberly Ann Tipton - San Francisco CA, US Jonathan Alexander Terrett - Lexington MA, US Shweta Singh - Fremont CA, US Annie Yang Weaver - San Mateo CA, US Luc Roland Desnoyers - San Francisco CA, US
The invention relates generally to antibodies that bind CD71, activatable antibodies that specifically bind to CD71 and methods of making and using these anti-CD71 antibodies and anti-CD71 activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
Antibodies That Bind Activatable Antibodies And Methods Of Use Thereof
The invention relates generally to antibodies and antigen-binding fragments thereof that bind activatable antibodies and/or conjugated activatable antibodies and methods of making and using these antibodies that bind activatable antibodies and/or conjugated activatable antibodies.
Anti-Cd166 Antibodies, Activatable Anti-Cd166 Antibodies, And Methods Of Use Thereof
- South San Francisco CA, US Jason Gary Sagert - San Mateo CA, US Jonathan Alexander Terrett - Cupertino CA, US Annie Yang Weaver - San Mateo CA, US Luc Roland Desnoyers - San Francisco CA, US Shweta Singh - Fremont CA, US
International Classification:
C07K 16/28 A61K 31/537 A61K 47/48
Abstract:
The invention relates generally to antibodies that bind CD166, activatable antibodies that specifically bind to CD166 and methods of making and using these anti-CD166 antibodies and anti-CD166 activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.
Anti-Itga3 Antibodies, Activatable Anti-Itga3 Antibodies, And Methods Of Use Thereof
- South San Francisco CA, US Jonathan Alexander Terrett - Cupertino CA, US Luc Roland Desnoyers - San Francisco CA, US Shweta Singh - Fremont CA, US Annie Yang Weaver - San Mateo CA, US
International Classification:
C07K 16/28 A61K 47/48
Abstract:
The invention relates generally to antibodies that bind ITGa3, activatable antibodies that specifically bind to ITGa3 and methods of making and using these anti-ITGa3 antibodies and anti-ITGa3 activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.