Anthony R Turner

US Patent:

20150269725, Sep 24, 2015

Filed:

Oct 17, 2013

Appl. No.:

14/436265

Inventors:

- Ann Arbor MI, US
- Detroit MI, US
- Fort Collins CO, US
Clifford M. Les - Birmingham MI, US
Bradford G. Orr - Ann Arbor MI, US
Elizabeth Goldstein - Ann Arbor MI, US
Anthony Turner - Fort Collins CO, US

International Classification:

G06T 7/00
G06K 9/52

Abstract:

Methods and systems for diagnosing a bone disease or other condition related to collagen in a subject are provided. These include providing a bone sample from the subject and determining a quantitative collagen morphology value of the bone sample. A reference value is provided from a non-affected control subject where the reference value is a quantitative collagen morphology value from the same type of bone sample obtained from a population of non-affected control subjects. The quantitative collagen morphology value of the subject's bone sample is compared to the reference value. If the collagen morphology value is altered versus the reference value, the subject is diagnosed as having a collagen related bone disease. The collagen morphology value can include mean fibril spacings and distributions of the fibril spacings taken from a subject's bone sample.