Antonio B Reyes

US Patent:

20130196334, Aug 1, 2013

Filed:

Mar 29, 2013

Appl. No.:

13/853897

Inventors:

Beckman Coulter, Inc. - Brea CA, US
Zihua Wang - Newton MA, US
Antonio Arevalo Reyes - Middleton MA, US
Erik Alan Gustafson - Norwood MA, US
John Steven Riley - Miami FL, US

Assignee:

Beckman Coulter, Inc. - Brea CA

International Classification:

G06F 19/12
C12Q 1/68

US Classification:

435 612, 703 11

Abstract:

A method for determining the presence of a biological entity. The method may include entering into a digital computer, at least a plurality of first input values associated with a first genetic element, a plurality of second input values associated with a second genetic element, and a plurality of third input values associated with a third genetic element associated with a plurality of samples. The method also includes determining a threshold value associated with the third genetic element, separating the samples using the threshold value into a first set of samples and a second set of samples, clustering the first set of samples in a feature space defined by the first genetic element and the second genetic element, defining a first boundary space using the first set of samples, and defining a second boundary space using the second set of samples.