Anu Abraham Mathew

US Patent:

8053198, Nov 8, 2011

Filed:

Sep 12, 2008

Appl. No.:

12/209701

Inventors:

Anu Mathew - North Potomac MD, US
Martin Stengelin - Gaithersburg MD, US
Eli Glezer - Chevy Chase MD, US

Assignee:

Meso Scale Technologies, LLC - Gaithersburg MD

International Classification:

G01N 33/53

US Classification:

435 71

Abstract:

The present invention relates to methods of diagnosing cancerous conditions in a patient, as well as methods of monitoring the progression of a cancerous condition and/or methods of monitoring a treatment protocol of a therapeutic agent or a chemotherapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

US Patent:

20030124572, Jul 3, 2003

Filed:

Jul 30, 2002

Appl. No.:

10/208526

Inventors:

Robert Umek - Silver Spring MD, US
Paula Eason - Germantown MD, US
Gargi Maheshwari - North Wales PA, US
Anu Mathew - Gaithersburg MD, US
Douglas Woods - Gaithersburg MD, US

Assignee:

favor of Meso Scale Technologies, LLC.

International Classification:

C12Q001/68
G01N033/53
G01N033/542

US Classification:

435/006000, 435/007900, 205/777500

Abstract:

Improved systems, system components, and methods for performing assays involving biological membranes and/or components thereof. Preferred luminescence test measurements are conducted using an assay module with integrated electrodes having biological membranes and/or components thereof immobilized thereon with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.

US Patent:

20210364505, Nov 25, 2021

Filed:

Aug 5, 2021

Appl. No.:

17/394512

Inventors:

- Rockville MD, US
Anu Mathew - North Potomac MD, US

Assignee:

Meso Scale Technologies, LLC. - Rockville MD

International Classification:

G01N 33/543
G01N 33/574

Abstract:

The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

US Patent:

20210349104, Nov 11, 2021

Filed:

Apr 30, 2021

Appl. No.:

17/246364

Inventors:

- Rockville MD, US
Anu MATHEW - North Potomac MD, US
James WILBUR - Germantown MD, US
Jeffery DEBAD - Ijamsville MD, US
Christopher CAMPBELL - Columbia MD, US
Hans BIEBUYCK - Potomac MD, US
Priscilla KRAI - Germantown MD, US
Alan KISHBAUGH - Rockville MD, US
Leonid DZANTIEV - Ellicott City MD, US
Christopher SHELBURNE - Rockville MD, US
Pu LIU - Rockville MD, US
Paul GOODWIN - Frederick MD, US
Adrian MCDERMOTT - Bethesda MD, US
Sarah O'CONNELL - Bethesda MD, US
Sandeep NARPALA - Bethesda MD, US

International Classification:

G01N 33/68

Abstract:

The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.

US Patent:

20200057070, Feb 20, 2020

Filed:

Oct 15, 2019

Appl. No.:

16/653268

Inventors:

- Rockville MD, US
Anu Mathew - North Potomac MD, US
Martin Stengelin - Gaithersburg MD, US
Mingyue Wang - Potomac MD, US

Assignee:

Meso Scale Technologies, LLC. - Rockville MD

International Classification:

G01N 33/574

Abstract:

The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a chemotherapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.

US Patent:

20200011866, Jan 9, 2020

Filed:

Aug 29, 2019

Appl. No.:

16/555271

Inventors:

- Rockville MD, US
- Bethesda MD, US
John Kenten - Boyds MD, US
Sudeep Kumar - Gaithersburg MD, US
Anu Mathew - North Potomac MD, US
Natalia I. Ossetrova - Silver Spring MD, US
George Sigal - Rockville MD, US

Assignee:

MESO SCALE TECHNOLOGIES, LLC - Rockville MD
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. - Bethesda MD

International Classification:

G01N 33/569
G01N 33/68
G01N 33/566

Abstract:

The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.

US Patent:

20180246100, Aug 30, 2018

Filed:

Feb 22, 2018

Appl. No.:

15/902597

Inventors:

- Rockville MD, US
- Bethesda MD, US
John Kenten - Boyds MD, US
Sudeep Kumar - Gaithersburg MD, US
Anu Mathew - North Potomac MD, US
Natalia I. Ossetrova - Silver Spring MD, US
George Sigal - Rockville MD, US

Assignee:

Meso Scale Technologies, LLC. - Rockville MD
THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. - Bethesda MD

International Classification:

G01N 33/569
G01N 33/566
G01N 33/68

Abstract:

The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.

US Patent:

20180088108, Mar 29, 2018

Filed:

Nov 15, 2017

Appl. No.:

15/813411

Inventors:

- Rockville MD, US
Anu Mathew - North Potomac MD, US

Assignee:

Meso Scale Technologies, LLC. - Rockville MD

International Classification:

G01N 33/543
G01N 33/574

Abstract:

The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.