Ariya Akthakul

US Patent:

7868087, Jan 11, 2011

Filed:

Sep 29, 2006

Appl. No.:

11/541629

Inventors:

Anne M. Mayes - Waltham MA, US
Jonathan F. Hester - Hudson WI, US
Pallab Banerjee - Boston MA, US
Ariya Akthakul - Boston MA, US

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

B01D 67/00
B01D 69/02
B01D 71/34
B01D 71/78

US Classification:

525 541, 525245, 525256, 525299, 525302, 525309, 21050027, 21050035, 21050042

Abstract:

The present invention relates to synthetic methods for grafting hydrophilic chains onto polymers, particularly hydrophobic polymers such as poly(vinyl chloride) (PVC), poly(vinylidene fluoride) (PVDF), and chlorinated polypropylene (cPP). Resulting polymers include comb polymers which can have a microphase-separated structure of hydrophilic domains provided by the hydrophilic chains. Articles prepared from these comb polymers, particularly derived from PVDF, include membranes for water filtration in which the hydrophilic domains provide a pathway for water transport. PVC can be plasticized by grafting the PVC with hydrophilic chains. In addition, such articles, particularly articles having biomedical applications, can display anti-thrombogenic properties.

US Patent:

7368505, May 6, 2008

Filed:

Jan 5, 2005

Appl. No.:

11/030576

Inventors:

Anne M. Mayes - Waltham MA, US
Jane Y. Park - Redwood City CA, US
Metin H. Acar - Istanbul, TR
Ariya Akthakul - Edison NJ, US

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

C08L 71/02
C08F 259/00
C08J 5/22

US Classification:

525118, 525353, 525535, 525536, 521 27, 521 30, 521 33, 521 34, 521 37

Abstract:

This invention relates to methods of making graft copolymers, and articles having such graft copolymers. The methods may provide better control than in radicalization or photoinitiated polymerization techniques. For example, a graft copolymer can be prepared by reacting an alkoxide ion with a polymer. The alkoxide, in turn, can be provided by any suitable technique, for example, by reacting an alcohol with a base. In some embodiments of the invention, the graft copolymers may be a normally hydrophobic polymer, such as a polysulfone, that has been made more hydrophilic due to the attachment of hydrophilic side groups such as polyethylene glycol or polypropylene glycol. The copolymers of the invention have many uses, for example, in films or porous membranes.

US Patent:

8562836, Oct 22, 2013

Filed:

Nov 30, 2010

Appl. No.:

12/957064

Inventors:

Jonathan F. Hester - Hudson WI, US
Pallab Banerjee - Roslindale MA, US
Ariya Akthakul - Boston MA, US
Glenn C. Mailand - Mustang OK, US

Assignee:

Massachusetts Institute of Technology - Cambridge MA

International Classification:

B01D 61/14
B01D 69/02
B01D 71/34
B01D 71/78
C08F 259/08

US Classification:

210650, 525 79, 525245, 525276

Abstract:

The present invention relates to synthetic methods for grafting hydrophilic chains onto polymers, particularly hydrophobic polymers such as poly(vinyl chloride) (PVC), poly(vinylidene fluoride) (PVDF), and chlorinated polypropylene (cPP). Resulting polymers include comb polymers which can have a microphase-separated structure of hydrophilic domains provided by the hydrophilic chains. Articles prepared from these comb polymers, particularly derived from PVDF, include membranes for water filtration in which the hydrophilic domains provide a pathway for water transport. PVC can be plasticized by grafting the PVC with hydrophilic chains. In addition, such articles, particularly articles having biomedical applications, can display anti-thrombogenic properties.

US Patent:

20020147282, Oct 10, 2002

Filed:

Sep 12, 2001

Appl. No.:

09/951125

Inventors:

Anne Mayes - Waltham MA, US
Jonathan Hester - Hudson WI, US
Pallab Banerjee - Boston MA, US
Ariya Akthakul - Cambridge MA, US

International Classification:

C08F259/00
C08F259/04
C08F259/06

US Classification:

525/245000, 525/276000, 525/292000

Abstract:

The present invention relates to synthetic methods for grafting hydrophilic chains onto polymers, particularly hydrophobic polymers such as poly(vinyl chloride) (PVC), poly(vinylidene fluoride) (PVDF), and chlorinated polypropylene (cPP). Resulting polymers include comb polymers which can have a microphase-separated structure of hydrophilic domains provided by the hydrophilic chains. Articles prepared from these comb polymers, particularly derived from PVDF, include membranes for water filtration in which the hydrophilic domains provide a pathway for water transport. PVC can be plasticized by grafting the PVC with hydrophilic chains. In addition, such articles, particularly articles having biomedical applications, can display anti-thrombogenic properties.

US Patent:

20220176013, Jun 9, 2022

Filed:

Apr 14, 2020

Appl. No.:

17/598030

Inventors:

- Tokyo, JP
Ariya Akthakul - Boston MA, US

International Classification:

A61L 26/00
A61K 8/895
A61K 8/19

Abstract:

Disclosed herein are compositions that can be used to create a thin film on the skin of a subject in a single application step to the skin of the subject. More specifically, a composition provided herein does not have to be stored in multiple compartments, nor mixed with another composition or component before application to the skin. Instead, a single composition can be manufactured, stored in a single compartment, and then applied to the skin of a subject to create a film on the skin of the subject. In certain embodiments, because there is no need to mix a composition provided herein prior to application to the skin, the container comprising a composition provided herein may also include an applicator suitable for application of the composition to the skin.