Barbara J Schmidt

US Patent:

20070098827, May 3, 2007

Filed:

Oct 31, 2005

Appl. No.:

11/262676

Inventors:

Christophe Ripoll - Saint-Andre, FR
Barbara Schmidt - Somerset NJ, US
Nebojsa Ilic - Highland Park NJ, US
Ilya Raskin - Manalapan NJ, US

International Classification:

A61K 36/28
A61K 31/365

US Classification:

424764000

Abstract:

A method of preparing a chicory extract enriched with sesquiterpene lactones is provided. The method includes performing an initial extraction chicory in a polar solvent, such as methanol or ethanol, at ambient temperature to form an alcoholic extract. The alcoholic extract is subsequently defatted with a non-polar solvent, preferably hexane or n-heptane. A second extraction of the defatted alcoholic extract is performed with a solvent which is more polar than the solvent used in the defatting process and less polar than the solvent used in the initial extraction, for example, it can be chosen from the group consisting of ethyl acetate, n-butanol, isopropanol, n-propanol, dichloromethane, acetonitrile, and mixtures thereof; resulting in a sesquiterpene lactones enriched extract, preferably containing at least 60% sesquiterpene lactones.

US Patent:

20080145465, Jun 19, 2008

Filed:

Oct 29, 2007

Appl. No.:

11/978704

Inventors:

Barbara M. Schmidt - Somerset NJ, US
Igor V. Belolipov - Tashkent, UZ
Anvar Kurmukov - Tashkent, UZ
Salakhutdin Zakirov - Tashkent, UZ
Ilya Raskin - Manalapan NJ, US

International Classification:

A61K 36/282
A61P 9/00
A61P 43/00
A61P 19/02
A61P 17/00

US Classification:

424764

Abstract:

The sesquiterpene lactone extract from is a potent anti-inflammatory agent in vivo. Methods of obtaining the anti-inflammatory extract and methods of treating inflammation with the extract are disclosed. A product comprising the total sesquiterpene lactone extract is useful for treatment of inflammation.

US Patent:

20110318403, Dec 29, 2011

Filed:

Nov 12, 2009

Appl. No.:

13/129077

Inventors:

Ilya Raskin - Manalapan NJ, US
Barbara Schmidt - Somerset NJ, US
Caren Villano - Hillsborough NJ, US
Leonel Eduardo Rojo Castillo - Brunswick NJ, US

Assignee:

Rutgers, The State University of New Jersey - New Brunswick NJ

International Classification:

A61K 9/70
A61K 8/97
A61Q 17/04
A61Q 19/08
A61P 17/02
A61P 31/00
A61P 17/10
A61Q 19/00
A61K 36/185
C12N 5/071

US Classification:

424443, 424776, 424 59, 435375, 424 74

Abstract:

A method of preparing extract was developed which comprises extracting oil from the nut. The lucuma nut oil (LNO) was effective to induce cell migration, enhance tissue regeneration and enhance wound healing. The lucuma nut oil provides an agent that is useful for therapeutic or cosmetic maintenance of skin and scalp.