Bengt G Persson

US Patent:

20200171435, Jun 4, 2020

Filed:

Nov 25, 2019

Appl. No.:

16/694997

Inventors:

Attila Herczeg - Southborough MA, US
Bengt G Persson - Boston MA, US
Julie-Anne Burdick - Hudson MA, US

International Classification:

B01D 61/04
B01D 61/58

Abstract:

Disclosed herein is a single pass cross flow diafiltration system comprising: a filtration module having; two or more filtration segments fluidly connected in series, each having an upstream side and a downstream side; wherein each filtration segment comprises hollow fiber filter membranes, and wherein each filtration segment has a selected length; wherein the hollow fiber filter membranes of each filtration segment have a selected inner diameter; wherein the selected inner diameter of each filtration segment may be the same or different, provided that at least one selected inner diameter differs from another selected inner diameter, and provided that the two or more filtration segments are arranged such that no selected inner diameter in a given filtration segment is larger on the upstream side; one or more pumps, mounted to urge fluid flow; and one or more points of introduction of a diadiluent, each of said points of introduction being fluidly connected to an upstream filtration segment.

US Patent:

20200016520, Jan 16, 2020

Filed:

Jul 11, 2018

Appl. No.:

16/033126

Inventors:

Attila Herczeg - Southborough, MA
Bengt G. Persson - Boston MA, US
Julie-Anne Burdick - Hudson MA, US

International Classification:

B01D 29/90
B01D 61/14
B01D 61/22
B01D 63/02
B01D 63/06

Abstract:

Disclosed herein is a single pass cross flow filtration system comprising: a filtration module comprising two or more filtration segments fluidly connected in series, each having an upstream side and a downstream side; wherein each filtration segment comprises hollow fiber filter membranes, and wherein, when in use, the desired permeate flux is controlled by a configuration comprising; each filtration segment having a selected length; the hollow fiber filter membranes of each filtration segment having a selected inner diameter, wherein the selected inner diameters may be the same or different, provided that at least one of the selected inner diameters differs from the others, and provided that the two or more filtration segments are arranged such that no inner diameter is larger on the upstream side; and one or more pumps, mounted in the permeate channel.