Stacie S. Canan Koch - La Jolla CA, US Therese N. Alexander - San Diego CA, US Benjamin J. Burke - San Diego CA, US Tanya M. Jewell - Encinitas CA, US David J. Kucera - Del Mar CA, US Maria Angelica Linton - San Diego CA, US Siegfried H. Reich - Solana Beach CA, US Donald J. Skalitzky - San Diego CA, US John H. Tatlock - San Diego CA, US Michael D. Varney - Solana Beach CA, US Scott C. Virgil - San Diego CA, US Stephen E. Webber - San Diego CA, US Stephen T. Worland - Del Mar CA, US Mark Barvian - Ann Arbor MI, US Gary Bolton - Ann Arbor MI, US Jeffrey J. Machak - Shelby Township MI, US Tod Holler - Ann Arbor MI, US Sean T. Murphy - Ypsilanti MI, US Michael Melnick - Ann Arbor MI, US Vara Prasad Josyula - Ann Arbor MI, US
Assignee:
Agouron Pharmaceuticals, Inc. - San Diego CA
International Classification:
C07D 207/16 C07D 221/02
US Classification:
546112, 546146, 548540, 514423
Abstract:
Compounds of the formula:.
Hiv Protease Inhibitors, Compositions Containing The Same, Their Pharmaceutical Uses And Materials For Their Synthesis
Therese Alexander - San Diego CA, US Mark Barvian - Ann Arbor MI, US Gary Bolton - Ann Arbor MI, US Frederick Boyer - Canton Township MI, US Benjamin Burke - San Diego CA, US Tod Holler - Ann Arbor MI, US Tanya Jewell - Encinitas CA, US Vara Prasad Josyula - Ann Arbor MI, US David Kucera - Del Mar CA, US Maria Linton - San Diego CA, US Jeffrey Machak - Shelby Township MI, US Lennert Mitchell - Chula Vista CA, US Sean Murphy - Ypsilanti MI, US Siegfried Reich - Solana Beach CA, US Donald Skalitzky - San Diego CA, US John Tatlock - San Diego CA, US Michael Varney - Solana Beach CA, US Scott Virgil - San Diego CA, US Stephen Webber - San Diego CA, US Stephen Worland - Del Mar CA, US Michael Melnick - Ann Arbor MI, US
Compounds of the formula: where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
Hiv Protease Inhibitors, Compositions Containing The Same, Their Pharmaceutical Uses And Materials For Their Synthesis
Stacie Canan Koch - La Jolla CA, US Therese Alexander - San Diego CA, US Benjamin Burke - San Diego CA, US Tanya Jewell - Encinitas CA, US David Kucera - Del Mar CA, US Maria Linton - San Diego CA, US Lennert Mitchell - Chula Vista CA, US Siegfried Reich - Solana Beach CA, US Donald Skalitzky - San Diego CA, US John Tatlock - San Diego CA, US Michael Varney - Solana Beach CA, US Scott Virgil - San Diego CA, US Stephen Webber - San Diego CA, US Stephen Worland - San Diego CA, US Mark Barvian - Ann Arbor MI, US Gary Bolton - Ann Arbor MI, US Frederick Boyer - Canton Township MI, US Jeffrey Machak - Shelby Township MI, US Tod Holler - Ann Arbor MI, US Sean Murphy - Ypsilanti MI, US Michael Melnick - Ann Arbor MI, US Vara Josyula - Ann Arbor MI, US
Compounds of the formula: where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
Hiv Protease Inhibitors, Compositions Containing The Same, Their Pharmaceutical Uses And Materials For Their Synthesis
Stacie Canan Koch - La Jolla CA, US Therese Alexander - San Diego CA, US Benjamin Burke - San Diego CA, US Tanya Jewell - Encinitas CA, US David Kucera - Del Mar CA, US Maria Linton - San Diego CA, US Lennert Mitchell - Chula Vista CA, US Siegfried Reich - Solana Beach CA, US Donald Skalitzky - San Diego CA, US John Tatlock - San Diego CA, US Michael Varney - Solana Beach CA, US Scott Virgil - San Diego CA, US Stephen Webber - San Diego CA, US Stephen Worland - San Diego CA, US Mark Barvian - Ann Arbor MI, US Gary Bolton - Ann Arbor MI, US Frederick Boyer - Canton Township MI, US Jeffrey Machak - Shelby Township MI, US Tod Holler - Ann Arbor MI, US Sean Murphy - Ypsilanti MI, US Michael Melnick - Ann Arbor MI, US Vara Josyula - Ann Arbor MI, US
Compounds of the formula: where the formula variables are as defined herein, are disclosed that advantageously inhibit or block the biological activity of the HIV protease. These compounds, as well as pharmaceutical compositions containing these compounds, are useful for treating patients or hosts infected with the HIV virus. Intermediates and synthetic methods for preparing such compounds are also described.
Macrocyclic Derivatives For The Treatment Of Diseases
Benjamin Joseph Burke - San Diego CA, US Michael Raymond Collins - San Diego CA, US Jingrong Jean Cui - San Diego CA, US Judith Gail Deal - Wildomar CA, US Robert Louis Hoffman - San Marcos CA, US Qinhua Huang - San Diago CA, US Ted William Johnson - Carlsbad CA, US Robert Steven Kania - San Diego CA, US John Charles Kath - La Mesa CA, US Phuong Thi Quy Le - San Diego CA, US Michele Ann McTigue - Encinitas CA, US Cynthia Louise Palmer - La Mesa CA, US Paul Francis Richardson - San Diego CA, US Neal William Sach - San Diego CA, US
- New York NY, US Paul Francis Richardson - San Diego CA, US Michael Raymond Collins - San Diego CA, US Daniel Tyler Richter - San Diego CA, US Benjamin Joseph Burke - San Diego CA, US Sacha Ninkovic - La Jolla CA, US Ketan Satish Gajiwala - San Diego CA, US Maria Angelica Linton - San Diego CA, US Phuong Thi Quy Le - San Diego CA, US Jacqui Elizabeth Hoffman - San Diego CA, US
International Classification:
C07D 401/14 C07D 471/04 C07D 487/04 C07D 405/14
Abstract:
Compounds of the general formula (I):processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.
Macrocyclic Derivatives For The Treatment Of Diseases
- New York NY, US Benjamin Joseph Burke - San Diego CA, US Michael Raymond Collins - San Diego CA, US Jingrong Jean Cui - San Diego CA, US Judith Gail Deal - Wildomar CA, US Robert Louis Hoffman - San Marcos CA, US Qinhua Huang - San Diego CA, US Ted William Johnson - Carlsbad CA, US Robert Steven Kania - San Diego CA, US John Charles Kath - La Mesa CA, US Phuong Thi Quy Le - San Diego CA, US Michele Ann McTigue - Encinitas CA, US Cynthia Louise Palmer - La Mesa CA, US Paul Francis Richardson - San Diego CA, US Neal William Sach - San Diego CA, US
Other researchers involved in the study are Kanghoon Jung, Sarah Krssel, Sooyeon Yoo, Benjamin Burke, Nicholas Schappaugh, Youngjin Choi and Seth Blackshaw of Johns Hopkins; Myungmo An of the Max Planck Florida Institute for Neuroscience; and Zirong Gu and Rui M. Costa of the Zuckerman Mind Brain B
Date: Oct 01, 2024
Category: Science
Source: Google
Students Raise Awareness for Social Conflicts at BC's Arts Fest Screening
The first documentary, Magnificity, by Benjamin Burke, MCAS 25, and Megan Malcolm, MCAS 24, opened the screening with a three-minute long film on the beauty of Boston. Shots focused on various aspects of what makes the city great, from its views to its people.