Benjamin D Miller

US Patent:

7226733, Jun 5, 2007

Filed:

Feb 21, 2002

Appl. No.:

10/082634

Inventors:

Selena Chan - Sunnyvale CA, US
Philippe M. Fauchet - Pittsford NY, US
Scott R. Horner - Rochester NY, US
Benjamin L. Miller - Rochester NY, US

Assignee:

University of Rochester - Rochester NY

International Classification:

C12Q 1/68
C12M 1/00
G01N 16/06
C07H 21/04

US Classification:

435 6, 435 71, 435174, 4352831, 4352878, 4352887, 422 681, 422 8205, 536 231, 536 243, 530300, 530350

Abstract:

A biological sensor which includes: a porous semiconductor structure comprising a central layer interposed between upper and lower layers, each of the upper and lower layers including strata of alternating porosity; and one or more probes coupled to the porous semiconductor structure, the one or more probes binding to a target molecule, whereby a detectable change occurs in a refractive index of the biological sensor upon binding of the one or more probes to the target molecule. Methods of making the biological sensor and methods of using the same are disclosed, as is a detection device which includes such a biological sensor.

US Patent:

54166489, May 16, 1995

Filed:

Mar 25, 1993

Appl. No.:

8/036823

Inventors:

David B. Jeppson - Livermore CA
Benjamin M. Miller - San Jose CA

Assignee:

Quantum Corporation - Milpitas CA

International Classification:

G11B 2719

US Classification:

360 7302

Abstract:

A hard disk drive spindle synchronization method comprises the steps of: sending an index marker pulse generated within each disk drive to mark in time a beginning of each rotation of the disk spindle thereof to a party line to which all drives are connected, rotating the disk spindle at a slightly different rotational velocity than any other drive of the array, monitoring drive pulses present on the spindle reference party line from other disk drives of the plurality to locate a center of gravity of pulse clusters which is within approximately plus or minus one quarter revolution of the drive's own index marker pulse, upon detection of a said center of gravity, ceasing to rotate the disk spindle at a slightly different rotational velocity during a second phase, adjusting the rotational phase of each drive to converge toward the center of gravity until all drive pulses present on the spindle reference party line converge into a single composite marker pulse present on the spindle reference party line, and maintaining convergence of the drive pulses during continuing operations of the disk drives by monitoring the spindle reference party line and making slight phase adjustments of the rotational phase of each drive, thereby phase locking all of the disk spindles of the plurality of hard disk drives to a single composite index marker signal present on the party line.