Stuart K. Williams - Tucson AZ, US James B. Hoying - Tucson AZ, US Benjamin R. Shepherd - Tucson AZ, US
Assignee:
Arizona Board of Regents on behalf of the University of Arizona - Tucson AZ
International Classification:
A01N 1/00 A01N 65/00 C12N 5/02 C12N 5/00
US Classification:
435 11, 424 931, 435325, 435395
Abstract:
This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs following implantation. The prevascularized constructs may also deliver genetically engineered gene products to the bloodstream.
Prevascularized Constructs For Implantation To Provide Blood Perfusion
Stuart K. Williams - Tucson AZ, US James B. Hoying - Tucson AZ, US Benjamin R. Shepherd - Tucson AZ, US
Assignee:
The Arizona Board of Regents on behalf of the University of Arizona - Tucson AZ
International Classification:
A01N 1/00 A01N 63/00 C12N 5/02 C12N 5/00
US Classification:
435 11, 424 931, 435325, 435395
Abstract:
This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs following implantation. The prevascularized constructs may also deliver genetically engineered gene products to the bloodstream.
Prevascularized Constructs For Implantation To Provide Blood Perfusion
Stuart Williams - Tucson AZ, US James Hoying - Tucson AZ, US Benjamin Shepherd - Tucson AZ, US
Assignee:
The Arizona Board of Regents on behalf of The University of Arizona - Tucson AZ
International Classification:
A61K 35/12 C12N 5/08
US Classification:
424093700, 435366000
Abstract:
This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs following implantation. The prevascularized constructs may also deliver genetically engineered gene products to the bloodstream.
Prevascularized Constructs For Implantation To Provide Blood Perfusion
This application discloses methods and materials for preparing functional microvascular beds in the laboratory. These prevascularized constructs can be used to vascularize engineered tissue constructs or to revascularize damaged or diseased tissues or organs following implantation. The prevascularized constructs may also deliver genetically engineered gene products to the bloodstream.
Platform For Engineered Implantable Tissues And Organs And Methods Of Making The Same
Keith Murphy - Palos Verdes Estates CA, US Chirag Khatiwala - San Diego CA, US Scott Dorfman - San Diego CA, US Benjamin Shepherd - San Diego CA, US Sharon Presnell - San Diego CA, US
Assignee:
ORGANOVO, INC. - San Diego CA
International Classification:
A61L 27/36 A01N 1/02 A61L 27/38
US Classification:
424400, 424 937, 424 933, 435 2, 427 224
Abstract:
Disclosed are engineered tissues and organs comprising one or more muscle cell-containing layers, the engineered tissue or organ consisting essentially of cellular material, provided that the engineered tissue or organ is implantable in a vertebrate subject and not a vascular tube.
Engineered Tissues For In Vitro Research Uses, Arrays Thereof, And Methods Of Making The Same
Keith Murphy - Palos Verdes Estates CA, US Chirag Khatiwala - San Diego CA, US Scott Dorfman - San Diego CA, US Benjamin Shepherd - San Diego CA, US Sharon Presnell - San Diego CA, US Justin Robbins - La Jolla CA, US
Disclosed are living, three-dimensional tissue constructs for in vitro scientific and medical research, arrays thereof, and methods of making said tissues and arrays.