Benjamin Wu

US Patent:

20070093889, Apr 26, 2007

Filed:

Aug 28, 2006

Appl. No.:

11/467847

Inventors:

Benjamin Wu - San Marino CA, US
Fernando Vinuela - Los Angeles CA, US
Yuichi Murayama - Los Angeles CA, US
Yuhuan Xu - Santa Monica CA, US

International Classification:

A61F 2/06

US Classification:

623001380

Abstract:

Non-fragmenting low friction bioactive absorbable coils are disclosed that improve long-term anatomic results in the endovascular treatment of intracranial aneurysms. The coils are composed of at least one biocompatible and bioabsorbable polymer. The coils are then coated with a polymer to reduce the friction. The coating can contain drugs, such as growth factors, and can be used to accelerate histopathologic transformation in aneurysms. The coil can be a polymer such as polyglycolic acid (PGA), poly-L-lactic acid (PLLA), polycaprolactive, poly-L-lactide, polydioxanone, polycarbonates, polyanhydrides, polyglycolic acid/poly-L-lactic acid copolymers, polyhydroxybutyrate/hydroxyvalerate copolymers, or combinations thereof.

US Patent:

20080290554, Nov 27, 2008

Filed:

Mar 31, 2005

Appl. No.:

10/593023

Inventors:

Benjamin M. Wu - Los Angeles CA, US
Michael V. Sofroniew - Los Angeles CA, US
Yuhuan Xu - Los Angeles CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

B29C 44/56

US Classification:

26421112, 4251748 E

Abstract:

Devices for fabricating oriented polymer fibers, and methods for fabricating thereof by electropulling, are provided.

US Patent:

20130069822, Mar 21, 2013

Filed:

Sep 19, 2011

Appl. No.:

13/236575

Inventors:

Benjamin Wu - Yorba Linda CA, US
Stephen R. Peck - West Hills CA, US
Shuwu Wu - Yorba Linda CA, US

International Classification:

G01S 19/41
G01S 19/07
G01S 19/55

US Classification:

34235724, 34235738, 34235744

Abstract:

A differential global positioning system (DGPS) processor can include an almost fixed integer ambiguity (AFIA) module for generating in real-time a multiple dimensional state vector of integer ambiguities and multiple dimensional corrections. The AFIA module can use double difference (DD) measurements for pseudo-range (PR) and carrier phase (CP) pairs generated from at least three global positioning system (GPS) receivers. A DGPS processor can be included in a high data rate real time attitude determination (RTAD) system to achieve high heading accuracy with high integrity.

US Patent:

20130072959, Mar 21, 2013

Filed:

Jul 18, 2012

Appl. No.:

13/552616

Inventors:

Benjamin M. Wu - San Marino CA, US
Fernando Vinuela - Los Angeles CA, US
Yuichi Marayama - Los Angeles CA, US
Yuhuan Xu - Santa Monica CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61M 29/00

US Classification:

606200

Abstract:

Non-fragmenting low friction bioactive absorbable coils are disclosed that improve long-term anatomic results in the endovascular treatment of intracranial aneurysms. The coils are composed of at least one biocompatible and bioabsorbable polymer. The coils are then coated with a polymer to reduce the friction. The coating can contain drugs, such as growth factors, and can be used to accelerate histopathologic transformation in aneurysms. The coil can be a polymer such as polyglycolic acid (PGA), poly-L-lactic acid (PLLA), polycaprolactive, poly-L-lactide, polydioxanone, polycarbonates, polyanhydrides, polyglycolic acid/poly-L-lactic acid copolymers, polyhydroxybutyrate/hydroxyvalerate copolymers, or combinations thereof.

US Patent:

20220252598, Aug 11, 2022

Filed:

Feb 16, 2022

Appl. No.:

17/673530

Inventors:

- Oakland CA, US
Yin To Chiu - Irvine CA, US
Benjamin Ming Wu - San Marino CA, US
Garrett L. Mosley - Newport Beach CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N 33/569
G01N 33/558
G01N 33/483
G01N 33/49
G01N 33/493

Abstract:

In various embodiments devices and methods for the detection and/or quantification of clinically relevant pathogens (e.g., bacteria, fungi, viruses, etc.) are provided. In certain embodiments the device comprises a lateral-flow assay that detects the bacterium at a concentration of less than about 6×10cells/mL, less than about 3×10cells/ml, less than about 1×10CFU/mL, or less than about 50 μg/mL. In certain embodiments the device comprises an aqueous two-phase system (ATPS) comprising a mixed phase solution that separates into a first phase solution and a second phase solution; and a lateral-flow assay (LFA). In certain embodiments the device comprises a flow-through system comprising a concentration component comprising an aqueous two-phase system (ATPS) comprising a mixed phase solution that separates into a first phase solution and a second phase solution; and a detection component disposed beneath said concentration component.

US Patent:

20210128791, May 6, 2021

Filed:

Oct 19, 2020

Appl. No.:

17/073945

Inventors:

- Oakland CA, US
Kang Ting - Los Angeles CA, US
Zhong Zheng - Van Nuys CA, US
Benjamin Wu - San Marino CA, US
Yulong Zhang - Los Angeles CA, US

International Classification:

A61L 27/54
A61L 27/04
A61L 27/06
A61L 31/16
A61L 27/08
A61L 31/02
A61N 1/20

Abstract:

The application discloses an implantable device, comprising a galvanic redox system formed on a body substrate of the implantable device. The implantable device has a non-zero surface potential when it is deployed. The galvanic redox system comprises a first metal site and a second metal site, the first metal site comprising a first metal having a first metal electrode potential (FMEP) and the second metal site comprising a second metal having a second metal electrode potential (SMEP), which FMEP being lower than SMEP and SMEP being substantially different such that the implantable device is galvanized when it is deployed. Methods of making and using the implantabe device are also disclosed.

US Patent:

20200284791, Sep 10, 2020

Filed:

Jan 23, 2020

Appl. No.:

16/751114

Inventors:

- Oakland CA, US
Yin To Chiu - Irvine CA, US
Benjamin Ming Wu - San Marino CA, US
Garrett L. Mosley - Newport Beach CA, US

International Classification:

G01N 33/558
G01N 33/543

Abstract:

Disclosed herein are devices and methods that use aqueous two phase systems and lateral flow assays to detect target analytes in a sample. These devices and methods may be used to diagnose a disease or condition in a biological sample, such as blood or serum. In addition, these devices and methods may be used to detect allergens in a food samples or contaminants, such as environmental toxins, in water samples. Device and kit components may be conveniently assembled in a portable container and are amenable to actuation in most settings. The devices are simple to use, requiring a non-trained operator to simply add the sample to the device. Conveniently, the time it takes to detect the target analyte is very short. Thus, the devices and methods disclosed herein provide novel and useful means for point-of-care.

US Patent:

20190391143, Dec 26, 2019

Filed:

Jun 6, 2019

Appl. No.:

16/434100

Inventors:

- Oakland CA, US
Yin To Chiu - Irvine CA, US
Benjamin Ming Wu - San Marino CA, US
Garrett L. Mosley - Newport Beach CA, US

International Classification:

G01N 33/558
G01N 33/543

Abstract:

Disclosed herein are devices and methods that use aqueous two phase systems and lateral flow assays to detect target analytes in a sample. These devices and methods may be used to diagnose a disease or condition in a biological sample, such as blood or serum. In addition, these devices and methods may be used to detect allergens in a food samples or contaminants, such as environmental toxins, in water samples. Device and kit components may be conveniently assembled in a portable container and are amenable to actuation in most settings. The devices are simple to use, requiring a non-trained operator to simply add the sample to the device. Conveniently, the time it takes to detect the target analyte is very short. Thus, the devices and methods disclosed herein provide novel and useful means for point-of-care.