Bin Qing Zheng from 210B Glen St, Glen Cove, NY 11542, age 56

Address:

291 Broadway #704, New York, NY 10007

License #:

003650 - Active

Category:

FILING REPRESENTATIVE

Issued Date:

Sep 27, 2012

Expiration Date:

Oct 11, 2019

Mk2 Inhibitors, The Synthesis Thereof, And Intermediates Thereto
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US Patent:

20220259222, Aug 18, 2022
Filed:

Jan 28, 2022
Appl. No.:

17/587555
Inventors:

- Summit NJ, US
John R. Coombs - New Brunswick NJ, US
Keming Zhu - New Brunswick NJ, US
Daniel Lim - Summit NJ, US
Candice Lee Joe - New Brunswick NJ, US
David T. George - New Brunswick NJ, US
Bin Zheng - Kendall Park NJ, US
Dong Lin - Monmouth Junction NJ, US
International Classification:

C07D 495/14
C07C 255/50
C07D 215/58
C07D 495/04
Abstract:

The present disclosure provides novel synthetic intermediates useful in the synthesis of MK2 kinase inhibitors.

Process For The Preparation Of N-((1R,2S,5R)-5-(Tert-Butylamino)-2-((S)-3-(7-Tert-Butylpyrazolo[1,5-A][1,3,5]Triazin-4-Ylamino)-2-Oxopyrrolidin-1-Yl)Cyclohexyl)Acetamide
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US Patent:

20220177482, Jun 9, 2022
Filed:

Feb 22, 2022
Appl. No.:

17/677312
Inventors:

- Princeton NJ, US
Collin Chan - New York NY, US
Joerg Deerberg - Columbus NJ, US
Nathan R. Domagalski - Niantic CT, US
Martin D. Eastgate - Titusville NJ, US
Yu Fan - Highland Park NJ, US
Michael David Bengt Fenster - New York NY, US
Robert V. Forest - Hillsborough NJ, US
Rebecca A. Green - Metuchen NJ, US
Matthew R. Hickey - Yardley PA, US
Nathaniel David Kopp - Newtown PA, US
Thomas E. La Cruz - Flemington NJ, US
Kathleen Lauser - Minneapolis MN, US
Hong Geun Lee - Seoul, KR
David K. Leahy - Hightstown NJ, US
Helen Y. Luo - San Francisco CA, US
Thomas M. Razler - Yardley PA, US
Scott A. Savage - Yardley PA, US
Chris Sfouggatakis - Staten Island NY, US
Maxime C.D. Soumeillant - Princeton NJ, US
Serge Zaretsky - Fords NJ, US
Bin Zheng - Kendall Park NJ, US
Ye Zhu - Singapore, SG
International Classification:

C07D 487/04
Abstract:

The invention generally relates to an improved process for the preparation of N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide,

Process For The Preparation Of N-((1R,2S,5R)-5-(Tert-Butylamino)-2-((S)-3-(7-Tert-Butylpyrazolo[1,5-A][1,3,5]Triazin-4-Ylamino)-2-Oxopyrrolidin-1-Yl)Cyclohexyl)Acetamide
view source
US Patent:

20200223852, Jul 16, 2020
Filed:

Jul 19, 2018
Appl. No.:

16/631915
Inventors:

- Princeton NJ, US
Collin Chan - New York NY, US
Joerg Deerberg - Columbus NJ, US
Nathan R. Domagalski - Niantic CT, US
Martin D. Eastgate - Titusville NJ, US
Yu Fan - Highland Park NJ, US
Michael David Bengt Fenster - New York NY, US
Robert V. Forest - Hillsborough NJ, US
Rebecca A. Green - Metuchen NJ, US
Matthew R. Hickey - Yardley PA, US
Nathaniel David Kopp - Newtown PA, US
Thomas E. La Cruz - Flemington NJ, US
Kathleen Lauser - Minneapolis MN, US
Hong Geun Lee - Seoul, KR
David K. Leahy - Hightstown NJ, US
Helen Y. Luo - San Francisco CA, US
Thomas M. Razler - Yardley PA, US
Scott A. Savage - Yardley PA, US
Chris Sfouggatakis - Staten Island NY, US
Maxime C.D. Soumeillant - Princeton NJ, US
Serge Zaretsky - Fords NJ, US
Bin Zheng - Kendall Park NJ, US
Ye Zhu - Singapore, SG
International Classification:

C07D 487/04
Abstract:

The invention generally relates to an improved process for the preparation of N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolodin-1-yl)cyclohexyl)acetamide, as well as novel intermediates employed in the process, which may be useful for the treatment of cancer.