James L. Zehnder - Menlo Park CA, US Bing Zhang - Fremont CA, US
International Classification:
C40B 30/04 C40B 30/00 G01N 33/566 C12Q 1/68
US Classification:
506 9, 435 611, 506 7, 435 612, 435 71, 435 792
Abstract:
Aspects of the subject invention are drawn to methods, compositions, systems and kits for the assessment of oxidative stress in an individual from a blood sample. In certain embodiments, the expression level of VNN1 in blood cells from a subject (or patient) is assessed and used to determine the subject's oxidative stress state, where an increased/high expression level of VNN1 indicates that the subject is in a state of oxidative stress. Expression of VNN1, and optionally other genes, may be done by assessing nucleic acid and/or protein levels in the blood cells obtained from the subject.
Method Of Manufacturing Cocrta/Cocrtapt Bi-Layer Magnetic Thin Films
Double layer, or bi-layer, magnetic films are deposited over a substrate with an underlayer. The bi-layer film is a film of two different magnetic layers which have different chemical composition, deposited with no spacer layer between the two layers. The lower magnetic layer should be of a low noise magnetic material, while the upper magnetic layer should be a high coercivity magnetic material. The bi-layer film exhibits a single response to magnetic recording and a joint coercivity different from the coercivity of either layer by itself. A preferred double layer media uses a CoCrTa layer deposited under a CoCrTaPt layer, with the CoCrTa layer comprising 30 to 70% of the total film thickness. The double layer film produces magnetic media with higher coercivity and lower media noise as compared to single layered films of either of the materials of the magnetic layers.
Double layer, or bi-layer, magnetic films are deposited over a substrate with an underlayer. The bi-layer film is a film of two different magnetic layers which have different chemical composition, deposited with no spacer layer between the two layers. The lower magnetic layer should be of a low noise magnetic material, while the upper magnetic layer should be a high coercivity magnetic material. The bi-layer film exhibits a single response to magnetic recording and a joint coercivity different from the coercivity of either layer by itself. A preferred double layer media uses a CoCrTa layer deposited under a CoCrTaPt layer, with the CoCrTa layer comprising 30 to 70% of the total film thickness. The double layer film produces magnetic media with higher coercivity and lower media noise as compared to single layered films of either of the materials of the magnetic layers.
Magnetic Recording Medium With Substantially Uniform Sub-Micron-Scale Morphology
Chuan Gao - Fremont CA Roger Klas Malmhall - Mountain View CA Bing Zhang - Fremont CA Kevin Grannen - Pacific CA Be Van Ho - San Jose CA
Assignee:
Seagate Technology, Inc. - Scotts Valley CA
International Classification:
G11B 566
US Classification:
428141
Abstract:
The signal-to-noise ratio of a magnetic recording medium having a thin magnetic layer is improved by adjusting the deposition conditions of the underlayer so that the magnetic layer is pseudo-epitaxially grown with a substantially uniform sub-micron-scale morphology. Uniform sub-micron-scale morphology can be attained by strategic selection of the underlayer and magnetic layer materials, and by controlling the underlayer deposition conditions so that the magnetic layer is epitaxially grown by a growth mechanism which is predominantly layer by layer. In an embodiment of the present invention, an underlayer comprising an alloy of chromium with vanadium, titanium or manganese, or an underlayer comprising a nickel-aluminum alloy, is sputter deposited at a pressure less than about 10 mTorr, substrate temperature greater than about 300. degree. C. and substrate bias greater than about 300 V, and a cobalt magnetic layer is epitaxially grown thereon, predominantly layer by layer.
A seed layer is deposited under an underlayer in magnetic thin film media. The seed layer material has a similar lattice parameter and a similar crystal structure to the underlayer material. The preferred structure involves a nickel-aluminum seed layer, under a chromium underlayer, under a cobalt-based magnetic layer. Use of the nickel-aluminum seed layer produces higher coercivity and lower media noise in the resultant magnetic thin film. The coercivity and media noise values for the resultant magnetic thin film are dependent upon deposition parameters, and recommended deposition parameters are given.
A seed layer is deposited under an underlayer in magnetic thin film media. The seed layer material has a similar lattice parameter and a similar crystal structure to the underlayer material. The preferred structure involves a nickel-aluminum seed layer, under a chromium underlayer, under a cobalt-based magnetic layer. Use of the nickel-aluminum seed layer produces higher coercivity and lower media noise in the resultant magnetic thin film. The coercivity and media noise values for the resultant magnetic thin film are dependent upon deposition parameters, and recommended deposition parameters are given.
- Ludwigshafen am Rhein, DE - Oakland CA, US Grit Baier - Ludwigshafen, DE Joshua C. Speros - Oakland CA, US Zhe Ji - Berkeley CA, US Bing Zhang - Berkeley CA, US Benjamin Breiten - Ludwigshafen, DE
Provided are compositions that include a metal-organic framework (MOF) including a framework defining an internal volume, an enzyme disposed within the internal volume, and a surfactant. Also provided are methods of making the compositions and their use.
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