Breanna L Dreiling from 1298 Red Mountain Dr, Longmont, CO 80504, age 42

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Location:

Longmont, CO

Industry:

Accounting

Method Of Detection Of Microorganisms With Enhanced Bacteriophage Amplification
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US Patent:

8455186, Jun 4, 2013
Filed:

Jun 13, 2008
Appl. No.:

12/663686
Inventors:

Jonathan Drew Smith - Boulder CO, US
Jon C. Rees - Snellville GA, US
Duane Bush - Fort Collins CO, US
Breanna Leigh Dreiling - Longmont CO, US
Maria Izzo - Longmont CO, US
Breanna Christine Smith - Lyons CO, US
Bernard Sportmann - Longmont CO, US
Tiffany Steinmark - Golden CO, US
Richard Proctor - Madison WI, US
Assignee:

MicroPhage™ Incorporated - Longmont CO
International Classification:

C12Q 1/70
C12Q 1/02
US Classification:

435 5, 435 29
Abstract:

A method of determining the presence or absence of a target microorganism in a sample to be tested, the method comprising: combining with the sample an amount of bacteriophage capable of attaching to the target microorganism to create a bacteriophage exposed sample, and a substance which enhances bacteriophage amplification or sensitivity; providing conditions to the bacteriophage-exposed sample sufficient to allow the bacteriophage to infect the microorganism; and assaying the bacteriophage-exposed sample to detect the presence or absence of a bacteriophage marker to determine the presence or absence of the target microorganism.

Method And Apparatus For Enhanced Sensitivity In Bacteriophage-Based Diagnostic Assays
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US Patent:

20090286232, Nov 19, 2009
Filed:

Jun 2, 2009
Appl. No.:

12/476796
Inventors:

Jonathan Drew Smith - Boulder CO, US
Breanna Leigh Dreiling - Longmont CO, US
Breanna Christine Smith - Lyons CO, US
John H. Wheeler - Boulder CO, US
Assignee:

MicroPhage™ Incorporated - Longmont CO
International Classification:

C12Q 1/70
US Classification:

435 5
Abstract:

A method of determining the presence or absence of a target microorganism in a sample to be tested, the method comprising: (a) combining with the sample an amount of bacteriophage capable of attaching to the target microorganism to create a bacteriophage-exposed sample; (b) providing conditions to the bacteriophage-exposed sample sufficient to allow the bacteriophage to attach to the target microorganism while inhibiting phage replication in a potentially cross-reactive, non-target microorganism; and (c) assaying the bacteriophage-exposed sample to detect the presence or absence of a bacteriophage marker to determine the presence or absence of the target microorganism; wherein the amount of the bacteriophage is between 10% to 70% of the threshold number of bacteriophage that the assay can detect, or between 1×10pfu/mL and 7×10pfu/mL.

Breanna L Dreiling