Brian A Brandt

US Patent:

6673107, Jan 6, 2004

Filed:

Dec 6, 1999

Appl. No.:

09/455592

Inventors:

Brian D. Brandt - San Jose CA
Joseph R. Callol - San Francisco CA
Hans F. Valencia - Sunnyvale CA

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61F 206

US Classification:

623 135

Abstract:

A Y-shaped stent, or bifurcated stent, for stenting bifurcated vessels consists of a first generally cylindrical distal branch defining a first flow path for fluid flow, and a second generally cylindrical distal branch defining a second flow path for fluid flow. The first and second distal branches are interconnected by one or more bending elements at a carina junction, each of the bending elements being flexible such that the first and second distal branches are capable of pivoting about the bending elements at the carina junction, thus defining an angle of varying degree. A generally cylindrical proximal branch defines a third flow path for fluid flow. The proximal branch is attached to the first and second distal branches proximate the carina junction such that the first and second distal branches and the proximal branch are in communication with each other.

US Patent:

6709440, Mar 23, 2004

Filed:

Jul 11, 2002

Appl. No.:

10/192981

Inventors:

Joseph R. Callol - San Francisco CA
Brian D. Brandt - San Jose CA
Nazanine Matin - Palo Alto CA
Hans F. Valencia - Holbrook MA
W. Stan Wilson - Missoula MT

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61M 2510

US Classification:

606108, 606194, 60410101, 623 111

Abstract:

The present invention provides for an improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The present invention includes a trap door stent design, a stent delivery catheter assembly, an apparatus for crimping the stent and the method for crimping the stent onto the catheter assembly, and the method for delivering and implanting the stent in a bifurcated vessel. More particularly, the invention relates to a stent having rings aligned along a common longitudinal axis and connected by links, where the stent has a proximal section, a distal section and a central section. The number of rings and the expanded diameter of the sections is varied to create a âtrap doorâ capable of expanding to a slightly larger diameter than the proximal section and distal section of the stent. The stent is implanted at a bifurcation so that the proximal section and distal section are in the main vessel, and the central section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel.

US Patent:

6749628, Jun 15, 2004

Filed:

May 17, 2001

Appl. No.:

09/861473

Inventors:

Joseph R. Callol - San Francisco CA
Brian D. Brandt - San Jose CA
Nazanine Matin - Palo Alto CA
Hans F. Valencia - Holbrook MA
W. Stan Wilson - Missoula MT
Steve Bigus - San Jose CA
David Chi - San Francisco CA
Brenda Cho - San Jose CA

Assignee:

Advanced Cardiovascular Systems, Inc. - Santa Clara CA

International Classification:

A61F 206

US Classification:

623 115, 623 135

Abstract:

The present invention provides for an improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The present invention includes a trap door stent design, a stent delivery catheter assembly, an apparatus for crimping the stent and the method for crimping the stent onto the catheter assembly, and the method for delivering and implanting the stent in a bifurcated vessel. More particularly, the invention relates to a stent having rings aligned along a common longitudinal axis and connected by links, where the stent has a proximal section, a distal section and a central section. The number of rings and the expanded diameter of the sections is varied to create a âtrap doorâ capable of expanding to a slightly larger diameter than the proximal section and distal section of the stent. The stent is implanted at a bifurcation so that the proximal section and distal section are in the main vessel, and the central section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel.

US Patent:

7381219, Jun 3, 2008

Filed:

Dec 23, 2003

Appl. No.:

10/746887

Inventors:

Amr Salahieh - Saratoga CA, US
Brian D. Brandt - Santa Clara CA, US
Dwight P. Morejohn - Davis CA, US
Ulrich R. Haug - Campbell CA, US
Jean-Pierre Dueri - Stockton CA, US
Hans F. Valencia - Berkeley CA, US
Robert A. Geshlider - San Francisco CA, US
Jeff Krolik - Campbell CA, US

Assignee:

Sadra Medical, Inc. - Campbell CA

International Classification:

A61F 2/24

US Classification:

623 211

Abstract:

Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.

US Patent:

7748389, Jul 6, 2010

Filed:

Oct 21, 2004

Appl. No.:

10/972287

Inventors:

Amr Salahieh - Saratoga CA, US
Brian D. Brandt - Santa Clara CA, US
Dwight P. Morejohn - Davis CA, US
Tom Saul - El Granada CA, US

Assignee:

Sadra Medical, Inc. - Los Gatos CA

International Classification:

A61F 2/24

US Classification:

128898, 623 126, 623 214

Abstract:

The present invention relates to apparatus for methods for endovascularly replacing a patient's heart valve. The apparatus includes an expandable anchor with leaflet engagement elements on the proximal end of the anchor and a replacement valve. The leaflet engagement elements can be used to prevent distal migration and insure proper positioning of the apparatus.

US Patent:

7824442, Nov 2, 2010

Filed:

Nov 5, 2004

Appl. No.:

10/982692

Inventors:

Amr Salahieh - Saratoga CA, US
Hans F. Valencia - San Jose CA, US
Brian D. Brandt - Santa Clara CA, US
Claudio Argento - Los Gatos CA, US
Ulrich R. Haug - Campbell CA, US
Jean-Pierre Dueri - Stockton CA, US
Daniel Hildebrand - Menlo Park CA, US
Dwight P. Morejohn - Davis CA, US
Tom Saul - El Granada CA, US

Assignee:

Sadra Medical, Inc. - Los Gatos CA

International Classification:

A61F 2/24

US Classification:

623 211

Abstract:

The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a sheath to a vicinity of the heart valve; deploying the anchor from the sheath; expanding the anchor with a deployment tool comprising a plurality of actuation elements to contact tissue at an anchor site; and retrieving the anchor into the sheath. Another aspect of the invention provides apparatus including a sheath; a deployment tool comprising a plurality of anchor actuation elements; a replacement valve configured to be disposed within the sheath for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the sheath for delivery to the vicinity of the heart valve, to be deployed from the sheath, to be expanded by the deployment tool to contact tissue at an anchor site and to be retrieved back into the sheath after having been expanded.

US Patent:

7824443, Nov 2, 2010

Filed:

Feb 2, 2006

Appl. No.:

11/275912

Inventors:

Amr Salahieh - Saratoga CA, US
Dwight Morejohn - Davis CA, US
Ulrich R. Haug - Campbell CA, US
Brian Brandt - San Jose CA, US
Hans Valencia - San Jose CA, US
Tom Saul - Moss Beach CA, US

Assignee:

Sadra Medical, Inc. - Los Gatos CA

International Classification:

A61F 2/24

US Classification:

623 211

Abstract:

An apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes a replacement heart valve implant comprising a valve and an expandable anchor; and a deployment tool adapted to endovascularly deliver the replacement heart valve implant to an implant site within the patient, the deployment tool comprising an actuator adapted to exert an axially directed force on the anchor. The invention also provides a method for endovascularly replacing a heart valve of a patient. In some embodiments, the method includes the steps of endovascularly delivering a replacement heart valve implant having a valve and an anchor to an implant site within the patient; and applying an axially directed force from an actuator outside of the patient to the anchor. In invention also provides deployment tools for performing the method.

US Patent:

7959666, Jun 14, 2011

Filed:

Nov 5, 2004

Appl. No.:

10/982388

Inventors:

Amr Salahieh - Saratoga CA, US
Jean-Pierre Dueri - Stockton CA, US
Hans F. Valencia - San Jose CA, US
Daniel Hildebrand - Menlo Park CA, US
Brian D Brandt - Santa Clara CA, US
Dwight P. Morejohn - Davis CA, US
Claudio Argento - Los Gatos CA, US
Tom Saul - El Granada CA, US
Ulrich R. Haug - Campbell CA, US

Assignee:

Sadra Medical, Inc. - Campbell CA

International Classification:

A61F 2/06
A61F 2/24

US Classification:

623 126

Abstract:

The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.