Brian Castle - Monroe CT, US Jianfei Yang - Sandy Hook CT, US Xiang Li - New Milford CT, US Jun Li - Danbury CT, US
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT
International Classification:
C12Q 1/68
US Classification:
435006000
Abstract:
A method of identifying genes involved in the stimulation of primary T cells comprising the steps of: a) contacting experimental cells with a stimulating agent; b) preparing RNA from said experimental cells at one or more stimulation phases; c) measuring the level of gene expression in the cells; d) comparing the levels of gene expression of said experimental cells to the level of gene expression in control cells that have not been exposed to an stimulation agent; e) identifying genes that are up regulated or down regulated in said experimental cells relative to said control cells.
B Cell Culture System Comprising High Density Membrane Bound Cd40 Ligand
Marilyn Kehry - Danbury CT Brian Castle - New Fairfield CT
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT
International Classification:
C12N 500 C12N 502 C07K 1452
US Classification:
435377
Abstract:
The present invention provides methods of proliferating B cells as a means of obtaining large numbers of B cells. The present invention further provides methods of differentiating a proliferating B cell population to antibody producing cells.
Methods For Proliferating And Differentiating B Cells With High Density Membrane Cd40 Ligand
Marilyn Kehry - Danbury CT Brian Castle - New Fairfield CT
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT
International Classification:
C12N 502 C12N 508
US Classification:
435377
Abstract:
The present invention provides methods of proliferating B cells as a means of obtaining large numbers of B cells. The present invention further provides methods of differentiating a proliferating B cell population to antibody producing cells.
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Santee Middle School San Diego CA 1983-1987, Santee Elementary School Santee CA 1985-1989, Grossmont Union High San Diego CA 1990-1992, Chaparral High School El Cajon CA 1990-1994
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