Brian C Vanderplas from 143 Washington Ave, Portland, ME 04101

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Location:

6 Craig Rd, Old Lyme, CT 06371

Industry:

Pharmaceuticals

Work:

Pfizer 1986 - 2011
Senior Scientist

Synthesis Of Carbamate Ketolide Antibiotics
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US Patent:

6403776, Jun 11, 2002
Filed:

Jul 5, 2000
Appl. No.:

09/610057
Inventors:

David H. B. Ripin - Westbrook CT
Brian C. Vanderplas - Old Lyme CT
Takushi Kaneko - Guilford CT
William T. McMillen - Fisher IN
Robert W. McLaughlin - Groton CT
Assignee:

Pfizer Inc. - New York NY
International Classification:

C07H 100
US Classification:

536 74, 536 185
Abstract:

The invention relates to a method of preparing a macrolide antibiotic of the formula wherein R , R , R , R , R are defined above. These antibiotics are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention also includes novel compounds made by the preparation of the macrolide antibiotic.

Process For Pyrrolidinyl Hydroxamic Acid Compounds
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US Patent:

60311142, Feb 29, 2000
Filed:

Aug 16, 1999
Appl. No.:

9/374869
Inventors:

Keith M. DeVries - Chester CT
Brian C. Vanderplas - Old Lyme CT
Assignee:

Pfizer Inc. - New York NY
International Classification:

C07D20712
US Classification:

548556
Abstract:

A method for preparing hydroxamic acid derivatives which are useful as analgesic, antiinflammatory, or neuroprotective agents.

Process And Intermediates For A .Beta..sub.3 -Adrenergic Receptor Agonist
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US Patent:

60909420, Jul 18, 2000
Filed:

Sep 29, 1999
Appl. No.:

9/408998
Inventors:

Keith M. DeVries - Chester CT
Jeffrey W. Raggon - Uncasville CT
Ravi M. Shanker - Groton CT
Frank J. Urban - Waterford CT
Brian C. Vanderplas - Old Lyme CT
Assignee:

Pfizer Inc. - New York NY
International Classification:

C07F 702
C07D40512
C07D40312
US Classification:

546 14
Abstract:

The instant invention relates to intermediates of Formula II, ##STR1## wherein R. sup. 1, R. sup. 2 and R. sup. 3 are as defined in the specification, and to processes for preparing such intermediates. This invention also relates to processes for preparing compounds of Formula III, ##STR2## and enantiomers thereof, wherein R. sup. 2, R. sup. 3 and R. sup. 4 are as defined in the specification. Compounds of Formula II and Formula III are intermediates in the preparation of a potent. beta. sub. 3 adrenergic receptor agonist. The instant invention also relates to processes for preparing the. beta. sub. 3 adrenergic receptor agonist using the compounds of Formula II and Formula III.

Process And Intermediates For A .Beta..sub.3 -Adrenergic Receptor Agonist
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US Patent:

61244570, Sep 26, 2000
Filed:

Jan 20, 2000
Appl. No.:

9/488245
Inventors:

Keith M. DeVries - Chester CT
Jeffrey W. Raggon - Uncasville CT
Ravi M. Shanker - Groton CT
Frank J. Urban - Waterford CT
Brian C. Vanderplas - Old Lyme CT
Assignee:

Pfizer Inc. - New York NY
International Classification:

C07F 702
C07D40502
C07D21174
C07D21353
US Classification:

546 14
Abstract:

The instant invention relates to intermediates of Formula II, ##STR1## wherein R. sup. 1, R. sup. 2 and R. sup. 3 are as defined in the specification, and to processes for preparing such intermediates. This invention also relates to processes for preparing compounds of Formula III, ##STR2## and enantiomers thereof, wherein R. sup. 2, R. sup. 3 and R. sup. 4 are as defined in the specification. Compounds of Formula II and Formula III are intermediates in the preparation of a potent. beta. sub. 3 adrenergic receptor agonist. The instant invention also relates to processes for preparing the. beta. sub. 3 adrenergic receptor agonist using the compounds of Formula II and Formula III.

Brian C Vanderplas