Bryan J Miller

US Patent:

7138625, Nov 21, 2006

Filed:

May 2, 2003

Appl. No.:

10/429234

Inventors:

Gregor T. Overney - Sunnyvale CA, US
Bryan D. Miller - Cupertino CA, US

Assignee:

Agilent Technologies, Inc. - Palo Alto CA

International Classification:

H01J 49/04
H01J 49/26

US Classification:

250288, 250281, 250282, 250423 P, 250423 R

Abstract:

Methods for specifying the layout of a MALDI sample plate are provided. In general, the methods involve creating a file containing sample plate layout parameters that describe the layout of a MALDI sample plate, and storing the file on a computer readable medium prior to placement of the MALDI sample plate into a MALDI ion source. In many embodiments, the file includes information about the size or shape of the sample plate, or information about the size, shape or position of a sample on the sample plate. In many embodiments, a MALDI sample plate is placed in a MALDI ion source and a stored layout file for the sample plate is accessed and used to position an area of the sample plate in a laser beam. The subject methods, kits and apparatus find use in a variety of different mass spectrometry applications.

US Patent:

7411183, Aug 12, 2008

Filed:

Feb 22, 2005

Appl. No.:

11/063486

Inventors:

Gregor T. Overney - Sunnyvale CA, US
Bryan D. Miller - Cupertino CA, US

Assignee:

Agilent Technologies, Inc. - Santa Clara CA

International Classification:

H01J 49/04
B01D 59/44

US Classification:

250282, 250288

Abstract:

Methods for specifying the layout of a MALDI sample plate are provided. In general, the methods involve creating a file containing sample plate layout parameters that describe the layout of a MALDI sample plate, and storing the file on a computer readable medium prior to placement of the MALDI sample plate into a MALDI ion source. In many embodiments, the file includes information about the size or shape of the sample plate, or information about the size, shape or position of a sample on the sample plate. In many embodiments, a MALDI sample plate is placed in a MALDI ion source and a stored layout file for the sample plate is accessed and used to position an area of the sample plate in a laser beam. The subject methods, kits and apparatus find use in a variety of different mass spectrometry applications.

US Patent:

20050139778, Jun 30, 2005

Filed:

Feb 22, 2005

Appl. No.:

11/063412

Inventors:

Gregor Overney - Sunnyvale CA, US
Bryan Miller - Cupertino CA, US

International Classification:

H01J027/00

US Classification:

25042300P, 25042300R

Abstract:

Methods for specifying the layout of a MALDI sample plate are provided. In general, the methods involve creating a file containing sample plate layout parameters that describe the layout of a MALDI sample plate, and storing the file on a computer readable medium prior to placement of the MALDI sample plate into a MALDI ion source. In many embodiments, the file includes information about the size or shape of the sample plate, or information about the size, shape or position of a sample on the sample plate. In many embodiments, a MALDI sample plate is placed in a MALDI ion source and a stored layout file for the sample plate is accessed and used to position an area of the sample plate in a laser beam. The subject methods, kits and apparatus find use in a variety of different mass spectrometry applications.

US Patent:

20060208187, Sep 21, 2006

Filed:

Mar 18, 2005

Appl. No.:

11/084830

Inventors:

Alex Mordehai - Santa Clara CA, US
Bryan Miller - Cupertino CA, US

International Classification:

H01J 49/42

US Classification:

250292000, 250281000, 250282000

Abstract:

The present invention relates to an apparatus and method for providing improved sensitivity and duty cycle in a mass spectrometry system. The mass spectrometry system of the present invention includes an ionization source, a mass analyzer/filter and an ion detector. The mass analyzer has a first trapping section, a second trapping section and a gating section interposed between the first trapping section and the second trapping section. The device may further include one or more lenses adjacent to the gating or trapping sections. The invention also provides an ion trap. The ion trap of the present invention has a first trapping section, a second trapping section and a gating section interposed between the first trapping section and the second trapping section. The gating and trapping sections may be in a linear arrangement. A method regarding the application of the present invention is also described. For instance, the method of the present invention includes ionizing a sample, trapping ions in a trapping section, selecting ions using a gating section and trapping ions in a second trapping section.