Brydon L. Bennett - San Diego CA, US Shripad S. Bhagwat - San Diego CA, US Anthony M. Manning - San Diego CA, US Brion W. Murray - San Diego CA, US Eoin C. O'Leary - San Diego CA, US Yoshitaka Satoh - San Diego CA, US
Assignee:
Signal Pharmaceuticals, LLC - San Diego CA
International Classification:
A61K 31/415
US Classification:
514406
Abstract:
This invention generally relates to methods for treating or preventing an inflammatory disease or disorder comprising administering to a patient in need thereof an effective amount of a Pyrazoloanthrone Derivative having the following structure:.
Methods Of Treatment And Prevention Using Haloaryl Substituted Aminopurines
Brydon Bennett - San Diego CA, US Shripad Bhagwat - San Diego CA, US Anthony Manning - San Diego CA, US Brion Murray - San Diego CA, US Eoin O'Leary - San Diego CA, US Yoshitaka Satoh - San Diego CA, US
International Classification:
C07D231/54 A61K031/416
US Classification:
514/406000, 548/358500
Abstract:
This invention generally relates to methods for treating or preventing an inflammatory disease or disorder comprising administering to a patient in need thereof an effective amount of a Pyrazoloanthrone Derivative having the following structure: or a pharmaceutically acceptable salt thereof, wherein Rand Rare as defined herein.
Brydon Bennett - San Diego CA, US David Brenner - New York NY, US Jerome Zeldis - Princeton NJ, US
International Classification:
A01N001/00
US Classification:
435001100, 514406000
Abstract:
The invention generally relates to methods for preserving tissue, preventing reperfusion injury to implanted tissue, preventing transplant rejection or preserving a cell to be transplanted, comprising contacting tissue or a cell with an effective amount of a JNK Inhibitor. The invention further relates to compositions useful for the preservation of tissue, the compositions comprising an effective amount of a JNK Inhibitor.
Methods For Treating, Preventing And Managing Chronic Lymphocytic Leukemia With Indazole Compounds
Brydon Bennett - San Diego CA, US Shripad Bhagwat - San Diego CA, US
International Classification:
A61K 31/454
US Classification:
514322000
Abstract:
This invention is generally directed to the use of Indazole Compounds for treating or preventing chronic lymphocytic leukemia. The methods comprise the treatment or prevention of chronic lymphocytic leukemia comprising administering an effective amount of an indazole compound, or a pharmaceutically acceptable salt or composition thereof, to a patient in need thereof.
Methods Of Treatment, Improvement And Prevention Using Haloaryl Substituted Aminopurines
Brydon L. Bennett - San Diego CA, US Brian Edwin Cathers - San Diego CA, US Heather Raymon - San Diego CA, US Weilin Xie - San Diego CA, US Jaman May Maroni - Watchung NJ, US
Provided herein are Aminopurine Compounds having the following structure:wherein R, Rand Rare as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing scleroderma, keloids, UV injury, or sunburn, and methods for improving or preventing scar formation.
Substituted Diaminocarboxamide And Diaminocarbonitrile Pyrimidines, Compositions Thereof, And Methods Of Treatment Therewith
Brydon L. Bennett - San Diego CA, US Jan Elsner - San Diego CA, US Paul Erdman - San Diego CA, US Robert Hilgraf - San Diego CA, US Laurie Ann LeBrun - San Diego CA, US Meg McCarrick - San Diego CA, US Mehran F. Moghaddam - Carlsbad CA, US Mark A. Nagy - San Diego CA, US Stephen Norris - San Diego CA, US David A. Paisner - Portland OR, US Marianne Sloss - San Diego CA, US William J. Romanow - San Diego CA, US Yoshitaka Satoh - Poway CA, US Jayashree Tikhe - San Diego CA, US Won Hyung Yoon - San Diego CA, US Mercedes Delgado - San Diego CA, US