Catherine A Finnegan

US Patent:

20090215778, Aug 27, 2009

Filed:

Apr 28, 2008

Appl. No.:

12/149178

Inventors:

Theodore J. Nitz - Boyds MD, US
Karl Salzwedel - Olney MD, US
Catherine Finnegan - Baltimore MD, US
Shirley Brunton - Windsor, GB
Stuart Flanagan - Wallingford, GB
Christian Montalbetti - Wallingford, GB
Thomas Stephen Coulter - Oxfordshire Wantage, GB

Assignee:

Panacos Pharmaceuticals, Inc. - Gaithersburg MD

International Classification:

C07D 487/04
A61K 31/496
A61K 31/519
A61K 31/5377
A61P 31/18

US Classification:

5142358, 544281, 51425216, 51425211, 544121

Abstract:

Derivatives of pyrazolopyrimidine compounds represented by Formula I are disclosed:These pyrazolopyrimidine derivatives and pharmaceutical compositions comprising these derivatives are useful in the treatment of HIV mediated diseases and conditions.

US Patent:

20070258970, Nov 8, 2007

Filed:

Dec 9, 2004

Appl. No.:

10/582411

Inventors:

Robert Blumenthal - Bethesda MD, US
Catherine Finnegan - Baltimore MD, US

International Classification:

A61K 31/165
A61K 31/07
A61K 31/20
A61K 31/203
A61K 38/46
A61P 31/18
C12Q 1/00

US Classification:

424094600, 435004000, 514559000, 514622000, 514725000

Abstract:

The present invention provides methods of preventing infection by retroviruses and methods of treatment of patients suffering from or susceptible to a viral infection. More particularly, the present invention provides methods of preventing viral infection and methods of treating retroviral infections which comprise the administration of at least one compound comprising N-4-(hydroxyphenyl)retinamide. Preferred methods of the invention are suitable for use in the treatment of patients who are HIV positive or are suffering from or are susceptible to AIDS.