Catherine Mary Mccarty

age ~52

from Murphy, NC

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Catherine Mccarty Phones & Addresses

Murphy, NC
Addison, IL

Us Patents

Cell Adhesion-Inhibiting Antiinflammatory Compounds
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US Patent:

6579882, Jun 17, 2003
Filed:

Mar 6, 2001
Appl. No.:

09/799729
Inventors:

Andrew O. Stewart - Libertyville IL
Steven A. Boyd - Mundelein IL
David L. Arendsen - Libertyville IL
Pramila Bhatia - Libertyville IL
Kevin R. Condroski - Evanston IL
Jennifer C. Freeman - Grayslake IL
Indrani W. Gunawardana - Libertyville IL
Kraig Lartey - Waukegan IL
Catherine M. McCarty - Brookline MA
Nicholas A. Mort - Highland Park IL
Meena V. Patel - Chicago IL
Michael A. Staeger - Greenfield WI
David M. Stout - Libertyville IL
Assignee:

Abbott Laboratories - Abbott Park IL
International Classification:

A61K 31519
US Classification:

514258, 544278
Abstract:

Compounds having Formula I are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of inhibiting/treating inflammatory diseases in a mammal.

Prostaglandin Endoperoxide H Synthase Biosynthesis Inhibitors
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US Patent:

7001895, Feb 21, 2006
Filed:

Apr 17, 2003
Appl. No.:

10/417959
Inventors:

Lawrence A. Black - Libertyville IL, US
Anwer Basha - Lake Forest IL, US
Teodozyj Kolasa - Lake Villa IL, US
Michael E. Kort - Lake Bluff IL, US
Huaqing Liu - Buffalo Grove IL, US
Catherine M. McCarty - Brookline MA, US
Meena Patel - Chicago IL, US
Jeffrey J. Rohde - Evanston IL, US
Michael J. Coghlan - Grayslake IL, US
Andrew O. Stewart - Libertyville IL, US
Assignee:

Abbott Laboratories - Abbott Park IL
International Classification:

A61K 31/50
A61K 31/675
C07D 237/16
US Classification:

514 85, 514247, 544232, 544240
Abstract:

The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important “housekeeping” enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).

Prostaglandin Endoperoxide H Synthase Biosynthesis Inhibitors
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US Patent:

7115591, Oct 3, 2006
Filed:

Jun 19, 2003
Appl. No.:

10/464928
Inventors:

Lawrence A. Black - Libertyville IL, US
Anwer Basha - Lake Forest IL, US
Teodozyj Kolasa - Lake Villa IL, US
Michael E. Kort - Lake Bluff IL, US
Huaqing Liu - Buffalo Grove IL, US
Catherine M. McCarty - Brookline MA, US
Meena Patel - Chicago IL, US
Jeffrey J. Rohde - Evanston IL, US
Michael J. Coghlan - Grayslake IL, US
Andrew O. Stewart - Libertyville IL, US
Assignee:

Abbott Laboratories - Abbott Park IL
International Classification:

A61K 31/50
A61K 31/675
C07D 237/16
C07F 9/6509
US Classification:

514 85, 514247, 544232, 544238, 544239, 544240, 544241
Abstract:

The present invention describes pyridazinone compounds of formula I.

Prostaglandin Endoperoxide H Synthase Biosynthesis Inhibitors
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US Patent:

20020013318, Jan 31, 2002
Filed:

May 31, 2001
Appl. No.:

09/871195
Inventors:

Lawrence Black - Libertyville IL, US
Anwer Basha - Lake Forest IL, US
Teodozyj Kolasa - Lake Villa IL, US
Michael Kort - Lake Bluff IL, US
Huaqing Liu - Buffalo Grove IL, US
Catherine McCarty - Brookline MA, US
Meena Patel - Chicago IL, US
Jeffrey Rohde - Evanston IL, US
Michael Coghlan - Grayslake IL, US
Andrew Stewart - Libertyville IL, US
International Classification:

A61K031/50
C07D237/14
US Classification:

514/248000, 544/240000
Abstract:

The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important “housekeeping” enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).

Prostaglandin Endoperoxide H Synthase Biosynthesis Inhibitors
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US Patent:

20020028938, Mar 7, 2002
Filed:

May 31, 2001
Appl. No.:

09/870838
Inventors:

Lawrence Black - Libertville IL, US
Anwer Basha - Lake Forest IL, US
Teodozyj Kolasa - Lake Villa IL, US
Michael Kort - Lake Bluff IL, US
Huaqing Liu - Buffalo Grove IL, US
Catherine McCarty - Brookline MA, US
Meena Patel - Chicago IL, US
Jeffrey Rohde - Evanston IL, US
Michael Coghlan - Grayslake IL, US
Andrew Stewart - Libertyville IL, US
International Classification:

C 07D 4 3/02
C07D237/14
US Classification:

544/238000, 544/239000
Abstract:

The present invention describes pyridazinone compounds of formula I which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important “housekeeping” enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).

Cell Adhesion-Inhibiting Antiinflammatory Compounds
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US Patent:

20030220365, Nov 27, 2003
Filed:

Mar 12, 2003
Appl. No.:

10/387317
Inventors:

Andrew Stewart - Libertyville IL, US
Steven Boyd - Mundelein IL, US
David Arendsen - Libertyville IL, US
Pramila Bhatia - Libertyville IL, US
Kevin Condroski - Evanston IL, US
Jennifer Freeman - Grayslake IL, US
Indrani Gunawardana - Libertyville IL, US
Kraig Lartey - Waukegan IL, US
Catherine McCarty - Brookline MA, US
Nicholas Mort - Highland Park IL, US
Meena Patel - Chicago IL, US
Michael Staeger - Greenfield WI, US
David Stout - Libertyville IL, US
International Classification:

C07D471/02
C07D491/02
C07D498/02
A61K031/4745
A61K031/4743
A61K031/4741
US Classification:

514/301000, 514/302000, 514/303000, 546/114000, 546/115000, 546/118000
Abstract:

Compounds having Formula I are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of inhibiting/treating inflammatory diseases in a mammal.

Prostaglandin Endoperoxide H Synthase Biosynthesis Inhibitors
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US Patent:

20090042888, Feb 12, 2009
Filed:

Jun 23, 2006
Appl. No.:

11/473633
Inventors:

Lawrence A. Black - Libertyville IL, US
Anwer Basha - Lake Forest IL, US
Teodozyj Kolasa - Lake Villa IL, US
Michael E. Kort - Lake Bluff IL, US
Huaqing Liu - Buffalo Grove IL, US
Catherine M. McCarty - Brookline MA, US
Meena Patel - Chicago IL, US
Jeffrey J. Rohde - Evanston IL, US
Michael J. Coghlan - Grayslake IL, US
Andrew O. Stewart - Libertyville IL, US
International Classification:

A61K 31/50
A61P 35/00
US Classification:

514247
Abstract:

The present invention describes pyridazinone compounds of formula Iwhich are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important “housekeeping” enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).

Prostaglandin Endoperoxide H Synthase Biosynthesis Inhibitors
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US Patent:

63070472, Oct 23, 2001
Filed:

Oct 27, 1999
Appl. No.:

9/427768
Inventors:

Lawrence A. Black - Libertyville IL
Anwer Basha - Lake Forest IL
Teodozyj Kolasa - Lake Villa IL
Michael E. Kort - Lake Bluff IL
Huaqing Liu - Buffalo Grove IL
Catherine M. McCarty - Brookline MA
Meena Patel - Chicago IL
Jeffrey J. Rohde - Evanston IL
Michael J. Coghlan - Grayslake IL
Andrew O. Stewart - Libertyville IL
Assignee:

Abbott Laboratories - Abbott Park IL
International Classification:

C07D23716
C07F 96509
A61K 3150
A61K 31675
US Classification:

544240
Abstract:

The present invention describes pyridazinone compounds of formula I ##STR1## which are cyclooxygenase (COX) inhibitors, and in particular, are selective inhibitors of cyclooxygenase-2 (COX-2). COX-2 is the inducible isoform associated with inflammation, as opposed to the constitutive isoform, cyclooxygenase-1 (COX-1) which is an important "housekeeping" enzyme in many tissues, including the gastrointestinal (GI) tract and the kidneys. The selectivity of these compounds for COX-2 minimizes the unwanted GI and renal side-effects seen with currently marketed non-steroidal anti-inflammatory drugs (NSAIDs).