- Seattle WA, US Roland B. Walter - Seattle WA, US Andre Lieber - Seattle WA, US Chang Li - Seattle WA, US
Assignee:
Fred Hutchinson Cancer Center - Seattle WA University of Washington - Seattle WA
International Classification:
C12N 15/113 C12N 5/00 C12N 5/0789 C12N 9/22
Abstract:
Systems and methods to selectively protect therapeutic cells by reducing CD33 expression in the therapeutic cells using base editors and targeting non-therapeutic cells with an anti-CD33 therapy are described. The selective protection results in the enrichment of the therapeutic cells while simultaneously targeting any diseased, malignant and/or non-therapeutic CD33 expressing cells within a subject.
Recombinant Ad35 Vectors And Related Gene Therapy Improvements
The present disclosure provides, among other things, helper-dependent adenoviral serotype 35 (Ad35) vectors. In various embodiments, helper-dependent Ad35 vectors can be used to deliver a therapeutic payload to a subject in need thereof. Exemplary payloads can encode replacement proteins, antibodies, CARs, TCRs, small RNAs, and genome editing systems. In certain embodiments, a helper-dependent Ad35 vector is engineered for integration of a payload into a host cell genome. The present disclosure further includes methods of gene therapy that include administration of a helper-dependent Ad35 vector to a subject in need thereof.
Queens Eye Center 6010 Main St FL 1, Flushing, NY 11355 (718)6618800 (phone), (718)4609351 (fax)
Languages:
Chinese English Korean Spanish
Description:
Dr. Li works in Flushing, NY and specializes in Optometry. Dr. Li is affiliated with New York Presbyterian Hospital Weill Cornell Medical Center and Queens Hospital Center.
Lanthier Winery Aug 2015 - Dec 2015
Statistical Analyst Intern
Jefferson County Government Jun 2015 - Dec 2015
Statistical Analyst
American Employees Association Embassy of the United States Jun 2014 - Aug 2014
Intern
Bellevue College Apr 2013 - Dec 2013
Coordinator
Bellevue College Jun 2012 - Dec 2013
Teaching Assistant
Education:
Purdue University 2014 - 2016
Bachelors, Statistics
Bellevue College 2011 - 2013
Associates, Associate of Arts, Mathematics
Skills:
V Lookups Powerpoint Social Media R Public Speaking Teaching Microsoft Sql Server English Jmp Pivot Tables Sas Microsoft Office Sql Server Integration Services Bloomberg Terminal Vba Time Management Customer Service Sql Python Teamwork Project Management Research Sql Server Reporting Services Spss Access
Languages:
Mandarin English Japanese
Assistant Vice President - Financial Solutions Advisor
Bank of America Merrill Lynch
Assistant Vice President - Financial Solutions Advisor
Scottrade Oct 2015 - Oct 2017
Bilingual Investment Consultant at Scottrade
Bank of America Jun 2014 - Oct 2015
Relationship Banker
Education:
Iit Stuart School of Business 2012 - 2014
Master of Science, Masters, Finance
Illinois Institute of Technology 2012 - 2013
Master of Science, Masters, Finance
Illinois Institute of Technology 2011 - 2012
Master of Science, Masters
University of Washington 2010 - 2012
Bachelors, Bachelor of Arts, Economics
North Seattle College 2008 - 2010
Series 7 Wa State Life, Disability, Variable Life & Variable Annuity Chartered Retirement Planning Counselor Series 63 Series 66 Test of Proficiency In Korean ( Topik Level Ii ) Open Water Diver License Crd6567164
Apple
Software Engineer - System
Megvii旷视 Jun 2018 - Sep 2018
Research Intern
New Oriental Education & Technology Group (Nyse:edu) Sep 2016 - May 2017
Toefl Teacher
Education:
University of Washington 2017 - 2018
Master of Science, Masters, Computer Engineering
Shanghai Jiao Tong University 2013 - 2017
Bachelors, Bachelor of Science, Electrical Engineering
University of Melbourne 2015 - 2015