Chang Chun Ma

US Patent:

20130029292, Jan 31, 2013

Filed:

May 21, 2012

Appl. No.:

13/476289

Inventors:

Kwei Mar - Taipei, TW
Chang M. Ma - Rockville MD, US
Rei-Min Chu - Taipei, TW

International Classification:

A61K 35/12
A61C 19/06
A61C 3/14
A61P 19/00

US Classification:

433215, 424 937

Abstract:

The present invention provides a method and compositions for tooth regeneration. Both implants of adipose-derived stem cell and dental pulp stem cell are able to grow self-assembled new teeth in extraction sockets when adding BMP2. The regenerated tooth is not only structurally similar to a normal tooth, but also well-developed in vascular and nervous systems with functions of growth, communication, and sensation. They are natural living teeth derived from this invented implantation method without any engineering procedure. It is ready for clinical testing and may be applied to future dental clinics.