Changfeng F Tai

US Patent:

20130006322, Jan 3, 2013

Filed:

Sep 30, 2010

Appl. No.:

13/497343

Inventors:

Changfeng Tai - Wexford PA, US

Assignee:

UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTE - PITTSBURGH PA

International Classification:

A61N 1/36
A61N 1/04

US Classification:

607 39, 607144, 607 40, 607 41

Abstract:

Provided herein are methods and devices useful for inhibiting or treating urological conditions, such as overactive bladder (OAB) symptoms including bladder overactivity, urinary frequency, urinary urgency, urinary incontinence, interstitial cystitis (IC), urinary retention, and pelvic pain; gastrointestinal conditions, such as fecal incontinence, irritable bowel syndrome (IBS), and constipation; and sexual conditions, such as premature ejaculation, erectile disorder, and female sexual arousal disorder by non-invasive transcutaneous electrical stimulation of the foot.

US Patent:

20090036945, Feb 5, 2009

Filed:

Aug 1, 2008

Appl. No.:

12/184518

Inventors:

Michael B. Chancellor - Pittsburgh PA, US
Changfeng Tai - Wexford PA, US

International Classification:

A61N 1/36

US Classification:

607 39, 607 41

Abstract:

Methods and apparatus are therefore provided herein for stimulating a desired physiological effect. The methods and apparatus can be used to control micturition, defecation and/or ejaculation. The methods and apparatus also can be used to control pain in the lower pelvic region, for example and without limitation, interstitial cystitis. The methods and apparatus also can be used to increase sexual sensation.

US Patent:

20210370059, Dec 2, 2021

Filed:

May 12, 2021

Appl. No.:

17/318110

Inventors:

- Pittsburgh PA, US
Changfeng Tai - Wexford PA, US

International Classification:

A61N 1/36
A61K 31/137
A61N 1/04
A61N 1/372
A61K 31/428
A61N 1/18
A61K 31/435
A61N 1/24
A61N 1/32
A61K 31/381

Abstract:

Provided herein are devices, systems, and methods for treating urological and gastrointestinal disorders, including bedwetting, through stimulation of the dorsal or plantar surface of the foot, including the superficial peroneal nerve and branches thereof, such as the dorsal intermediate and medial cutaneous nerves, or the medial and/or and lateral plantar nerves. The device facilitates placement of electrodes on the foot. Also provided herein is a system including the device, a pulse generator, and a controller, and methods of manufacturing and using the same.

US Patent:

20210290429, Sep 23, 2021

Filed:

Jun 4, 2021

Appl. No.:

17/339481

Inventors:

- Pittsburgh PA, US
Changfeng Tai - Wexford PA, US

International Classification:

A61F 7/00
A61F 7/02

Abstract:

Provided herein are methods of nerve blockage, for example for treatment of obesity, heart failure, cardiovascular disease, muscle spasms, chronic pain, or urinary retention in a patient. The method comprises first heating a nerve above physiological temperature (e.g., 37 C. in a human), such as from 43 C. to 54 C. for a duration that leads to reversible nerve blockage as opposed to nerve damage. Second, reversible nerve blockage is produced by cooling the nerve below physiological temperature to a temperature in which reversible nerve blockage is achieved, for example from 15 C. to 30 C.

US Patent:

20210283401, Sep 16, 2021

Filed:

May 26, 2021

Appl. No.:

17/330883

Inventors:

- Pittsburgh PA, US
Changfeng Tai - Wexford PA, US

International Classification:

A61N 1/36
A61N 1/05

Abstract:

Provided herein is a method of blocking a nerve or neuron by applying an electrical stimulation to the nerve or neuron, wherein the electrical stimulation is of an intensity below the excitation threshold of the nerve or neuron for a length of time sufficient to produce a block of nerve conduction or neuron excitation.

US Patent:

20210106831, Apr 15, 2021

Filed:

Apr 15, 2019

Appl. No.:

17/047754

Inventors:

- Pittsburgh PA, US
Changfeng Tai - Wexford PA, US

International Classification:

A61N 1/36
A61N 1/05

Abstract:

Provided herein is a method of blocking a nerve or neuron by applying an electrical stimulation to the nerve or neuron, wherein the electrical stimulation is of an intensity below the excitation threshold of the nerve or neuron for a length of time sufficient to produce a block of nerve conduction or neuron excitation.

US Patent:

20200114149, Apr 16, 2020

Filed:

May 13, 2019

Appl. No.:

16/410206

Inventors:

- Pittsburgh PA, US
Changfeng Tai - Wexford PA, US

International Classification:

A61N 1/36

Abstract:

Provided herein are methods and devices useful for inhibiting or treating urological conditions, such as overactive bladder (OAB) symptoms including bladder overactivity, urinary frequency, urinary urgency, urinary incontinence, interstitial cystitis (IC), urinary retention, and pelvic pain; gastrointestinal conditions, such as fecal incontinence, irritable bowel syndrome (IBS), and constipation; and sexual conditions, such as premature ejaculation, erectile disorder, and female sexual arousal disorder by non-invasive transcutaneous electrical stimulation of the foot.

US Patent:

20200069940, Mar 5, 2020

Filed:

May 2, 2018

Appl. No.:

16/609883

Inventors:

- Pittsburgh PA, US
Changfeng Tai - Wexford PA, US

International Classification:

A61N 1/36
A61N 1/04

Abstract:

Provided herein are methods for treating underactive bladder, urinary retention, detrusor-sphincter dyssynergia after spinal cord injury, constipation, and/or infrequent bowel movements including the step of applying electrical stimulation to one or more peripheral nerves.