Chao Fang

US Patent:

20190284140, Sep 19, 2019

Filed:

May 30, 2019

Appl. No.:

16/426674

Inventors:

- Cambridge MA, US
Chao Fang - Cambridge MA, US

International Classification:

C07D 215/12
C07D 405/02
C07D 401/14
C07D 215/04
A61K 31/47
C07D 405/14
A61P 31/06
C07D 405/04
C07D 409/14
C07D 409/04
C07D 407/14
C07D 407/04
C07D 401/06
C07D 215/14
C07D 413/04
C07D 401/04
C07D 215/48
C07D 401/02

Abstract:

The present invention provides compounds for the treatment of a bacterial infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the treatment of a bacterial infection in a subject.

US Patent:

20190270723, Sep 5, 2019

Filed:

Nov 30, 2018

Appl. No.:

16/207062

Inventors:

- Waltham MA, US
Jennifer C. Petter - Stow MA, US
Jonathan Craig Blain - Melrose MA, US
Donovan Noel Chin - Lexington MA, US
Chao Fang - Lexington MA, US
Herschel Mukherjee - Somerville MA, US
Neil Kubica - Swampscott MA, US

International Classification:

C07D 401/14
G01N 33/50
A61K 47/68
C12N 15/115
A61K 47/54
A61P 25/28
A61P 43/00
C07D 495/04
A61K 9/00

Abstract:

The present invention relates to photoactivatable compounds and methods of use thereof for determining binding site and other structural information about RNA transcripts. The invention also provides methods of identifying RNA transcripts that bind compounds and are thus druggable, methods of screening drug candidates, and methods of determining drug binding sites and/or accessible or reactive sites on a target RNA.

US Patent:

20180237394, Aug 23, 2018

Filed:

Aug 12, 2016

Appl. No.:

15/751968

Inventors:

- Cambridge MA, US
Chao Fang - Cambridge MA, US

International Classification:

C07D 215/12
A61P 31/06
C07D 401/04
C07D 409/14
C07D 401/14
C07D 215/14
C07D 413/04
C07D 405/04
C07D 409/04
C07D 405/14
C07D 401/06

Abstract:

The present invention provides compounds for the treatment of a bacterial infection. Additionally, the present invention provides compositions and methods for using these compounds and compositions in the treatment of a bacterial infection in a subject.