Charles B Lawrence

US Patent:

6725621, Apr 27, 2004

Filed:

Apr 23, 2001

Appl. No.:

09/840498

Inventors:

Ross K. Hill - Houston TX
Paul J. Grimes - Katy TX
Charles E. Lawrence - Houston TX

Assignee:

Canatxx Energy, L.L.C. - Houston TX

International Classification:

E04B 100

US Classification:

5274502, 290 2

Abstract:

The present invention is an improved power generation facility and method of construction. The improved power generation facility of the present invention provides a low impact implementation suitable for placement in or near a developed, populated area comprising ultimate consumers. The improved power generation facility comprises a foundation; a plurality of legs which form a support structure capable of supporting a plurality of condenser modules with cooling fans of predetermined size; and a housing for containing predetermined power generation equipment, the housing fitting inside the support structure and having a facade which can be made to blend into a surrounding environments architecture. In a preferred mode, the legs are tricolumn legs that may be removably fastened to each other and to the foundation. Further, the housing may be suspended from the support structure and the plurality of cooling fans situated to minimize noise from the cooling fans.

US Patent:

7156899, Jan 2, 2007

Filed:

Apr 26, 2004

Appl. No.:

10/833894

Inventors:

Ross K. Hill - Houston TX, US
Paul J. Grimes - Katy TX, US
Charles E. Lawrence - Houston TX, US

Assignee:

Canatxx Energy, L.L.C. - Houston TX

International Classification:

B03C 3/014

US Classification:

95 67, 95 73, 95 78, 96 44, 96 50, 96 63, 96 88, 290 2, 290 52

Abstract:

The present invention provides a power generation facility that is adapted to clean large air masses. Air from the environment, which normally contains the most pollutants, is directed into an air flow path through which large quantities of air are directed by a plurality of large diameter fans. The large air flow is directed through electrically insulated cooling fins which cool heated gas from power generators. The electrically insulated cooling fans have a voltage applied thereto and act as electrodes used to produce an electric field that attracts particles such as pollutants. In a preferred embodiment, a charging section is utilized within the air flow prior to the electrically insulated cooling fins to charge the particles with a charge opposite to the voltage applied to the cooling fins to thereby attract the particles to the cooling fins. A cooling fin washing system with pressurized jets is provided in one embodiment to wash the pollutants from the surface of the cooling fins.

US Patent:

7381749, Jun 3, 2008

Filed:

Jun 9, 2005

Appl. No.:

11/150783

Inventors:

James William Malecha - San Diego CA, US
Stewart Alwyn Noble - San Diego CA, US
Christian Andreus Hassig - Mira Mesa CA, US
Paul L. Wash - San Diego CA, US
Brandon M. Wiley - Philadelphia PA, US
Charles Maxwell Lawrence - San Diego CA, US
Timothy Z. Hoffman - San Diego CA, US

Assignee:

Kalypsys, Inc. - San Diego CA

International Classification:

A61K 31/18
C07C 303/00

US Classification:

514601, 514513, 514602, 564 84

Abstract:

Disclosed herein are carbonyl compounds of having the structural formula:Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central nervous system disorders, neurodegenerative disorders, fibrosis, bone disorders, polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, cardiovascular conditions, and disorders in which angiogenesis play a role in pathogenesis, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.

US Patent:

7470722, Dec 30, 2008

Filed:

Jun 9, 2005

Appl. No.:

11/150500

Inventors:

James William Malecha - San Diego CA, US
Stewart Alwyn Noble - San Diego CA, US
Christian Andreus Hassig - Mira Mesa CA, US
Paul L. Wash - San Diego CA, US
Brandon M. Wiley - Philadelphia PA, US
Charles Maxwell Lawrence - San Diego CA, US
Timothy Z. Hoffman - San Diego CA, US

Assignee:

Kalypsys, Inc. - San Diego CA

International Classification:

A61K 31/35
C07D 319/14

US Classification:

514456, 549362, 549462, 548484, 5483027, 546139, 546134, 546246, 544159, 544339, 544381, 514464, 514396, 5142522, 514315

Abstract:

Disclosed herein are carbonyl compounds of Formula I as described herein. Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central nervous system disorders, neurodegenerative disorders, fibrosis, bone disorders, polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, cardiovascular conditions, and disorders in which angiogenesis play a role in pathogenesis, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.

US Patent:

20050038776, Feb 17, 2005

Filed:

Aug 15, 2003

Appl. No.:

10/643204

Inventors:

Ramin Cyrus - Vienna VA, US
Matteo Tommaso - Gaithersburg MD, US
Anthony Kerlavage - Montgomery Village MD, US
Charles Lawrence - Rockville MD, US

International Classification:

G06F017/30

US Classification:

707003000

Abstract:

An online life science research environment and virtual community with a focus on design and analysis of biological experiments includes a life sciences laboratory system employing at least one networked computer system that defines a virtual research environment. Users access the system through a portal associated with the networked computer system(s). The virtual research environment has a data coupling mechanism by which the user designates a set of user-specified data for bioinformatics processing. A processor(s) associated with the networked computer system(s) performs bioinformatics services upon the user-specified data. In one embodiment, the data coupling mechanism enables transfer of the user-specified data to a memory space that is mediated or accessed by the processor performing the bioinformatics processing. Users may thus exploit bioinformatics processing resources that are not deployed on users' local computer environments, and to store and organize information relating to life sciences research in a secure, online workspace.

US Patent:

20080194681, Aug 14, 2008

Filed:

Dec 9, 2005

Appl. No.:

11/792624

Inventors:

James Malecha - San Diego CA, US
Stewart Noble - San Diego CA, US
Christian Hassig - Mira Mesa CA, US
Paul Wash - San Diego CA, US
Brandon Wiley - Philadelpha PA, US
Charles Lawrence - San Diego CA, US
Timothy Hoffman - San Diego CA, US
Celine Bonnefous - San Diego CA, US
NIcholas Smith - San Diego CA, US

Assignee:

Kalypsys, Inc. - San Diego CA

International Classification:

A61K 31/265
C07C 327/32
A61P 9/00
A61P 7/06
A61P 35/00
A61P 35/04

US Classification:

514513, 558253

Abstract:

Disclosed herein are carbonyl compounds of Formula: (I) as described herein. Compounds as modulators of his-tone deacetylase (HDAC), pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.

US Patent:

20090063259, Mar 5, 2009

Filed:

Sep 10, 2008

Appl. No.:

12/207909

Inventors:

Ramin Cyrus - Vienna VA, US
Matteo Di Tommaso - Gaithersburg MD, US
Anthony R. Kerlavage - Montomery Village MD, US
Charles B. Lawrence - Rockville MD, US

International Classification:

G06Q 30/00
G06F 17/30
G06Q 10/00
G06Q 50/00

US Classification:

705 11, 707102, 705 26, 707E17002

Abstract:

An online life science research environment and virtual community with a focus on design and analysis of biological experiments includes a life sciences laboratory system employing at least one networked computer system that defines a virtual research environment. Users access the system through a portal associated with the networked computer system(s). The virtual research environment has a data coupling mechanism by which the user designates a set of user-specified data for bioinformatics processing. A processor(s) associated with the networked computer system(s) performs bioinformatics services upon the user-specified data. In one embodiment, the data coupling mechanism enables transfer of the user-specified data to a memory space that is mediated or accessed by the processor performing the bioinformatics processing. Users may thus exploit bioinformatics processing resources that are not deployed on users' local computer environments, and to store and organize information relating to life sciences research in a secure, online workspace.

US Patent:

63202719, Nov 20, 2001

Filed:

Jun 21, 2000

Appl. No.:

9/598182

Inventors:

Ross K. Hill - Houston TX
Paul J. Grimes - Katy TX
Charles E. Lawrence - Houston TX

Assignee:

Canatxx Energy, L.L.C. - Houston TX

International Classification:

B60L 102

US Classification:

290 2

Abstract:

The present invention is an improved power generation facility and method of construction. The improved power generation facility of the present invention provides a low impact implementation suitable for placement in or near a developed, populated area comprising ultimate consumers. The improved power generation facility comprises a foundation; a plurality of legs which form a support structure capable of supporting a plurality of condenser modules with cooling fans of predetermined size; and a housing for containing predetermined power generation equipment, the housing fitting inside the support structure and having a facade which can be made to blend into a surrounding environment's architecture. In a preferred mode, the legs are tricolumn legs that may be removably fastened to each other and to the foundation. Further, the housing may be suspended from the support structure and the plurality of cooling fans situated to minimize noise from the cooling fans.

Address:

3707 Knollwood St, Houston, TX 77019

Phone:

(713)3208262

VIN:

WDDDJ72X17A095485

Make:

MERCEDES-BENZ

Model:

CLS-CLASS

Year:

2007