Charles J Romano

US Patent:

6501009, Dec 31, 2002

Filed:

Aug 19, 1999

Appl. No.:

09/377466

Inventors:

Charles P. Romano - Medfield MA

Assignee:

Monsanto Technology LLC - St. Louis MO

International Classification:

A01H 510

US Classification:

800302, 800279, 800288, 8003201, 4353201, 435418, 435419, 435412, 4352523, 536 2317

Abstract:

The present invention discloses methods and compositions comprising a group of novel expression cassettes which provide significantly improved levels of accumulation of Coleopteran inhibitory Cry3B and Cry3B variant amino acid sequences when these are expressed in plants. The preferred embodiments of the invention provide at least up to ten fold higher levels of insect controlling protein relative to the highest levels obtained using prior compositions. In particular, transgenic maize expressing higher levels of a protein designed to exhibit increased toxicity toward Coleopteran pests deliver superior levels of insect protection and are less likely to sponsor development of populations of target insects that are resistant to the insecticidally active protein.

US Patent:

6943281, Sep 13, 2005

Filed:

Aug 29, 2002

Appl. No.:

10/232665

Inventors:

Charles P. Romano - Medfield MA, US

Assignee:

Monsanto Technology LLC - St. Louis MO

International Classification:

A01H005/00
A01H005/10
C12N015/82
C12N015/32

US Classification:

800302, 800279, 4353201, 435418, 536 2371, 424 932

Abstract:

The present invention discloses methods and compositions comprising a group of novel expression cassettes which provide significantly improved levels of accumulation of Coleopteran inhibitory Cry3B and Cry3B variant amino acid sequences when these are expressed in plants. The preferred embodiments of the invention provide at least up to ten fold higher levels of insect controlling protein relative to the highest levels obtained using prior compositions. In particular, transgenic maize expressing higher levels of a protein designed to exhibit increased toxicity toward Coleopteran pests deliver superior levels of insect protection and are less likely to sponsor development of populations of target insects that are resistant to the insecticidally active protein.

US Patent:

7408096, Aug 5, 2008

Filed:

Jul 29, 2005

Appl. No.:

11/192801

Inventors:

Charles P. Romano - Medfield MA, US

Assignee:

Monsanto Technology LLC - St. Louis MO

International Classification:

A01H 5/00
A01H 5/10
C12N 15/82
C12N 15/32

US Classification:

800302, 536 2371, 424 932, 424405, 435419, 435412, 435440, 435468, 4353201, 800279

Abstract:

The present invention discloses methods and compositions comprising a novel expression cassette providing significantly improved levels of accumulation of inhibitory Cry3B variant protein when expressed in maize plants. The preferred embodiments of the invention provide at least up to ten fold higher levels of insect controlling protein relative to the highest levels obtained using prior compositions. In particular, transgenic maize expressing higher levels of a protein designed to exhibit increased toxicity toward pests deliver superior levels of insect protection and are less likely to sponsor development of populations of target insects that are resistant to the insecticidally active protein.

US Patent:

8101826, Jan 24, 2012

Filed:

Mar 30, 2010

Appl. No.:

12/749943

Inventors:

Charles P. Romano - Medfield MA, US

Assignee:

Monsanto Technology LLC - St. Louis MO

International Classification:

A01H 5/00
C12N 15/82
C12N 15/32
C12N 1/21

US Classification:

800302, 536 2371, 435412, 4353201, 435455, 424 932, 800279, 8003201

Abstract:

The present invention discloses methods and compositions comprising a group of novel expression cassettes which provide significantly improved levels of accumulation of Coleopteran inhibitory Cry3B and Cry3B variant amino acid sequences when these are expressed in plants. The preferred embodiments of the invention provide at least up to ten fold higher levels of insect controlling protein relative to the highest levels obtained using prior compositions. In particular, transgenic maize expressing higher levels of a protein designed to exhibit increased toxicity toward Coleopteran pests deliver superior levels of insect protection and are less likely to sponsor development of populations of target insects that are resistant to the insecticidally active protein.

US Patent:

20090019609, Jan 15, 2009

Filed:

Aug 1, 2008

Appl. No.:

12/184444

Inventors:

Charles P. Romano - Medfield MA, US

International Classification:

A01H 5/00

US Classification:

800302

Abstract:

The present invention discloses methods and compositions comprising a group of novel expression cassettes which provide significantly improved levels of accumulation of inhibitory Cry3B and Cry3B variant amino acid sequences when these are expressed in plants. The preferred embodiments of the invention provide at least up to ten fold higher levels of insect controlling protein relative to the highest levels obtained using prior compositions. In particular, transgenic maize expressing higher levels of a protein designed to exhibit increased toxicity toward pests deliver superior levels of insect protection and are less likely to sponsor development of populations of target insects that are resistant to the insecticidally active protein.