Shiv Srivastava - Potomac MD, US Albert Dobi - Columbia MD, US Taduru Sreenath - Germantown MD, US Gyorgy Petrovics - Bethesda MD, US Chen Sun - Bethesda MD, US
Assignee:
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. - Bethesda MD
International Classification:
C12Q 1/68
US Classification:
435 61
Abstract:
The disclosure describes alterations in ERG gene expression. ERG isoforms and promoter sequence of the ERG gene that are involved in, or associated with, prostate cancer are provided. The disclosure further provides therapeutic compositions and methods of detecting, diagnosing, prognosing, and treating prostate cancer, including biomarkers for detecting the expression of two or more of the following genes: PSA/KLK3, PMEPA1, NKX3. 1, ODC1, AMD1, and ERG.
Prostate Cancer-Specific Alterations In Erg Gene Expression And Detection And Treatment Methods Based On Those Alterations
Shiv Srivastava - Potomac MD, US Albert Dobi - Columbia MD, US Taduru Sreenath - Germantown MD, US Gyorgy Petrovics - Bethesda MD, US Chen Sun - Bethesda MD, US
Alterations in ERG gene expression can be observed in patients with prostate cancer. Specific ERG isoforms are associated with, or involved in, prostate cancer. Compositions comprising these isoforms provide therapeutic benefit and can be used in methods of detecting, diagnosing, prognosing, and treating prostate cancer. These compositions provide biomarkers for detecting the expression of combinations of the PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1, and ERG genes.
Prostate Cancer-Specific Alterations In Erg Gene Expression And Detection And Treatment Methods Based On Those Alterations
- Bethesda MD, US Albert L. Dobi - Rockville MD, US Taduru Sreenath - Germantown MD, US Gyorgy Petrovics - Bethesda MD, US Chen Sun - Bethesda MD, US
International Classification:
C12N 15/113 C12Q 1/68
Abstract:
Alterations in ERG gene expression can be observed in patients with prostate cancer. Specific ERG isoforms are associated with, or involved in, prostate cancer. Compositions comprising these isoforms provide therapeutic benefit and can be used in methods of detecting, diagnosing, prognosing, and treating prostate cancer. These compositions provide biomarkers for detecting the expression of combinations of the PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1 and ERG genes.
Prostate Cancer-Specific Alterations In Erg Gene Expression And Detection And Treatment Methods Based On Those Alterations
- Bethesda MD, US Albert Dobi - Rockville MD, US Taduru Sreenath - Germantown MD, US Gyorgy Petrovics - Bethesda MD, US Chen Sun - Bethesda MD, US
Assignee:
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. - Bethesda MD
International Classification:
C12Q 1/68
US Classification:
435 611
Abstract:
The disclosure describes alterations in ERG gene expression. ERG isoforms and promoter sequence of the ERG gene that are involved in, or associated with, prostate cancer are provided. The disclosure further provides therapeutic compositions and methods of detecting, diagnosing, prognosing, and treating prostate cancer, including biomarkers for detecting the expression of two or more of the following genes: PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1, and ERG.
Risk Analyst at Castleton Commodities International
Location:
Stamford, Connecticut
Industry:
Financial Services
Work:
Castleton Commodities International - Stamford since Jul 2013
Risk Analyst
UBS Global Asset Management - Stamford Feb 2013 - Jul 2013
Data Analyst
Genworth Financial - New York May 2012 - Aug 2012
Asset Management Intern
Darwin Fenner Student Managed Fund Feb 2010 - May 2010
Stock Analyst
Burkenroad Reports Sep 2009 - Jan 2010
Research Equity Analyst
Education:
Columbia University - Fu Foundation School of Engineering and Applied Science 2011 - 2012
Master of Science in Financial Engineering, Financial Engineering
Tulane University 2007 - 2011
Master, Accounting & Finance & Mathematics
Zhejiang University 2006 - 2007
NA, NA
Hangzhou Foreign Language School 2003 - 2006
High School, Science
Interests:
classical music, musicals, gourmet cooking, nutrition planning, Chinese traditional medicine, aerobics, baseball, Japanese, piano, basketball
Honor & Awards:
Distinguished Scholars Award
Dean’s Honor List
Phi Eta Sigma National Honor Society Scholarship
Director's Award (For highest GPA graduating senior) (Tulane)
Languages:
Chinese English Japanese
Certifications:
CFA Level III Candidate Microsoft Office Specialist Certification for Excel, Word, PowerPoint, Access, Microsoft