The present invention relates to microspheres comprising hyaluronan derivatized with a bifunctional crosslinker to form microspheres. Methods of making such microspheres, comprising mixing hyaluronic acid and a dihydrazide with a crosslinker in an aqueous solution, adding a solvent and an emulsifying agent to form an emulsion, and lowering the pH of the emulsion to allow intramolecular and intermolecular crosslinking to occur, are also disclosed. The invention also provides for pharmaceutical or cosmetic formulations based on the microspheres described herein, further containing one or more active or cosmetic agents, and methods of using such formulations.
Philip Dehazya - Westbury NY, US Cheng Lu - Livingston NJ, US
Assignee:
Clear Solutions Biotech, Inc.
International Classification:
A61K031/00 C08B037/00 A61K031/728
US Classification:
514/001000, 514/054000, 536/053000
Abstract:
The present invention relates to microspheres comprising hyaluronan derivatized with a bifunctional crosslinker to form microspheres. Methods of making such microspheres, comprising mixing hyaluronic acid and a dihydrazide with a crosslinker in an aqueous solution, adding a solvent and an emulsifying agent to form an emulsion, and lowering the pH of the emulsion to allow intramolecular and intermolecular crosslinking to occur, are also disclosed. The invention also provides for pharmaceutical or cosmetic formulations based on the microspheres described herein, further containing one or more active or cosmetic agents, and methods of using such formulations.
Multi-Dimensional Burst Link Access Streaming Transmission (Blast) Architecture And Algorithms For Low Latency Real-Time Broadband Burst Data/Video Transmission
Cheng Lu - Rego Park NY, US Richard Locarni - Stony Brook NY, US Richard Hummel - E. Patchogue NY, US Frank Haunstein - Wading River NY, US Michael Dombrowski - Wantagh NY, US
Assignee:
Data Device Corporation - Bohemia NY
International Classification:
H04L 23/02
US Classification:
375261000, 375260000
Abstract:
A multi-dimensional Burst Link Access Streaming Transmission (BLAST) architecture, which provides flexible physical apparatus for balanced performance of data throughput, latency, and reliability of transmission (e.g. graceful degradation). A schedule is sent from a master node to alert targeted nodes regarding messages to be sent. The master node uses a P-Band transmission link operating a regular intervals to synchronize the system in preparation for receipt of a message over a synchronous link. Each node has the capability of sending and receiving synchronous and asynchronous messages.
Drought Tolerant Plants And Related Constructs And Methods Involving Genes Encoding Dtp6 Polypeptides
Stephen M. Allen - Wilmington DE, US Jason L. Brothers - Newark DE, US Krupa Deshmukh - Hyderabad, IN Honor Renee Lafitte - Davis CA, US Xiao-Yi Li - Wilmington DE, US Cheng Lu - Newark DE, US Stanley Luck - Wilmington DE, US Jeffrey Mullen - Newark DE, US Hajime Sakai - Newark DE, US James J. Saylor - Newark DE, US Scott V. Tingey - Wilmington DE, US Robert Wayne Williams - Hockessin DE, US
Assignee:
E I DU PONT DE NEMOURS AND COMPANY - Wilmington DE
Isolated polynucleotides and polypeptides and recombinant DNA constructs useful for conferring drought tolerance, compositions (such as plants or seeds) comprising these recombinant DNA constructs, and methods utilizing these recombinant DNA constructs. The recombinant DNA construct comprises a polynucleotide operably linked to a promoter that is functional in a plant, wherein said polynucleotide encodes a DTP6 polypeptide.
May 2013 to 2000 Teacher, Nationalities ServiceESL Philadelphia, PA May 2013 to Jun 2013 Teacher, SEAMAACPEDAL at Graduate School of Education
Jan 2013 to May 2013 English FacilitatorPAS Philadelphia, PA Sep 2012 to Dec 2012 English TutorNew Oriental School Wuhan, CN Jan 2012 to Feb 2012 TeacherZhejiang University
Sep 2011 to Jan 2012 Chinese Tutor26 Middle School Wuhan, CN Jul 2011 to Aug 2011 Intern English Teacher, NO
Education:
University of Pennsylvania, Graduate School of Education Philadelphia, PA Mar 2014 Master of ScienceZhejiang University Hangzhou, CN Jun 2012 Bachelor of English Language & LiteratureUniversity of Copenhagen Kbenhavn Jun 2012 Bachelor of Business Administration
Stevens Institute of Technology Hoboken, NJ 2011 to 2013 Master of Engineering in Electrical EngineeringTianjin University 2007 to 2011 BS in Electrical Engineering
Skills:
C/C++, C#, Java, Shell Script, SQL, Linux (Fedora, Ubuntu), FreeBSD, Git, GDB, Data Structure, Algorithm, Database Management, Assembly Language, Qt Creator, PostgreSQL, Android, Programming on ARM
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