Cheng H Lu

US Patent:

6969531, Nov 29, 2005

Filed:

Aug 26, 2003

Appl. No.:

10/649082

Inventors:

Philip Dehazya - Westbury NY, US
Cheng Lu - Livingston NJ, US

Assignee:

Engelhard Corporation - Iselin NJ

International Classification:

C08B037/00
A61K009/50

US Classification:

424493, 536 54, 536115, 536118, 536124, 514 54, 424489

Abstract:

The present invention relates to microspheres comprising hyaluronan derivatized with a bifunctional crosslinker to form microspheres. Methods of making such microspheres, comprising mixing hyaluronic acid and a dihydrazide with a crosslinker in an aqueous solution, adding a solvent and an emulsifying agent to form an emulsion, and lowering the pH of the emulsion to allow intramolecular and intermolecular crosslinking to occur, are also disclosed. The invention also provides for pharmaceutical or cosmetic formulations based on the microspheres described herein, further containing one or more active or cosmetic agents, and methods of using such formulations.

US Patent:

20030096734, May 22, 2003

Filed:

Dec 5, 2002

Appl. No.:

10/310629

Inventors:

Philip Dehazya - Westbury NY, US
Cheng Lu - Livingston NJ, US

Assignee:

Clear Solutions Biotech, Inc.

International Classification:

A61K031/00
C08B037/00
A61K031/728

US Classification:

514/001000, 514/054000, 536/053000

Abstract:

The present invention relates to microspheres comprising hyaluronan derivatized with a bifunctional crosslinker to form microspheres. Methods of making such microspheres, comprising mixing hyaluronic acid and a dihydrazide with a crosslinker in an aqueous solution, adding a solvent and an emulsifying agent to form an emulsion, and lowering the pH of the emulsion to allow intramolecular and intermolecular crosslinking to occur, are also disclosed. The invention also provides for pharmaceutical or cosmetic formulations based on the microspheres described herein, further containing one or more active or cosmetic agents, and methods of using such formulations.

US Patent:

20080013640, Jan 17, 2008

Filed:

Jan 31, 2007

Appl. No.:

11/700359

Inventors:

Cheng Lu - Rego Park NY, US
Richard Locarni - Stony Brook NY, US
Richard Hummel - E. Patchogue NY, US
Frank Haunstein - Wading River NY, US
Michael Dombrowski - Wantagh NY, US

Assignee:

Data Device Corporation - Bohemia NY

International Classification:

H04L 23/02

US Classification:

375261000, 375260000

Abstract:

A multi-dimensional Burst Link Access Streaming Transmission (BLAST) architecture, which provides flexible physical apparatus for balanced performance of data throughput, latency, and reliability of transmission (e.g. graceful degradation). A schedule is sent from a master node to alert targeted nodes regarding messages to be sent. The master node uses a P-Band transmission link operating a regular intervals to synchronize the system in preparation for receipt of a message over a synchronous link. Each node has the capability of sending and receiving synchronous and asynchronous messages.