Sun Cheng () (died 132) was an eunuch during Han Dynasty who, contrary to the stereotypes of Han eunuchs being corrupt and power-hungry, was loyal to the
State University of New York at Binghamton 2009 - 2013
Master of Arts (MA), Anthropology
State University of New York at Binghamton 2009 - 2013
Master of Science (MS), Biomedical Anthropology
- Oakland CA, US Jonathan A. ELLMAN - Guilford CT, US Fanqing Frank CHEN - Moraga CA, US Kai-Hang SU - Chungho, TW Cheng SUN - Wilmette IL, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
G01N 21/65 C12Q 1/37
Abstract:
A nanoplasmonic resonator (NPR) comprising a metallic nanodisk with alternating shielding layer(s), having a tagged biomolecule conjugated or tethered to the surface of the nanoplasmonic resonator for highly sensitive measurement of enzymatic activity. NPRs enhance Raman signals in a highly reproducible manner, enabling fast detection of protease and enzyme activity, such as Prostate Specific Antigen (paPSA), in real-time, at picomolar sensitivity levels. Experiments on extracellular fluid (ECF) from paPSA-positive cells demonstrate specific detection in a complex bio-fluid background in real-time single-step detection in very small sample volumes.