Cheng Kong Wu

US Patent:

6467476, Oct 22, 2002

Filed:

May 18, 2000

Appl. No.:

09/574168

Inventors:

Yehuda Ivri - Irvine CA
Cheng H. Wu - Sunnyvale CA

Assignee:

Aerogen, Inc. - Sunnyvale CA

International Classification:

A61M 1600

US Classification:

12820016, 12820312

Abstract:

The invention provides methods and apparatus for nebulizing liquids. In one exemplary embodiment, an apparatus is provided which comprises a thin shell member having a front surface, a rear surface, and a plurality of apertures extending therebetween. The apertures are tapered to narrow from the rear surface to the front surface. A liquid supplier is further provided which delivers a predetermined unit volume of liquid to the rear surface. A vibrator vibrates the thin shell member to eject liquid droplets from the front surface of the thin shell member.

US Patent:

6640804, Nov 4, 2003

Filed:

Aug 15, 2002

Appl. No.:

10/222178

Inventors:

Yehuda Ivri - Irvine CA
Cheng H. Wu - Sunnyvale CA

Assignee:

Aerogen, Inc. - Mountain View CA

International Classification:

A61M 1600

US Classification:

12820016, 12820312

Abstract:

The invention provides methods and apparatus for nebulizing liquids. In one exemplary embodiment, an apparatus is provided which comprises a thin shell member having a front surface, a rear surface, and a plurality of apertures extending therebetween. The apertures are tapered to narrow from the rear surface to the front surface. A liquid supplier is further provided which delivers a predetermined unit volume of liquid to the rear surface. A vibrator vibrates the thin shell member to eject liquid droplets from the front surface of the thin shell member.

US Patent:

6755189, Jun 29, 2004

Filed:

May 18, 1999

Appl. No.:

09/313914

Inventors:

Yehuda Ivri - Irvine CA
Linda R. De Young - El Granada CA
Cheng H. Wu - Sunnyvale CA
Miro S. Cater - Daytona Beach FL
Vijay Kumar - Sunnyvale CA
Markus Flierl - Sunnyvale CA

Assignee:

Aerogen, Inc. - Mountain View CA

International Classification:

B05B 1706

US Classification:

12820016, 12820014

Abstract:

The invention provides exemplary aerosolization apparatus and methods for aerosolizing a substance. According to one exemplary method, a liquid is transferred from a first chamber into a second chamber having a substance that is in a dry state to form a solution. The solution is then transferred from the second chamber and onto an atomization member. The atomization member is operated to aerosolize the solution.

US Patent:

6782886, Aug 31, 2004

Filed:

Mar 20, 2001

Appl. No.:

09/812988

Inventors:

Sharad Narayan - Sunnyvale CA
Yehuda Ivri - Irvine CA
Cheng H. Wu - Sunnyvale CA
Miro S. Cater - Daytona Beach FL

Assignee:

Aerogen, Inc. - Mountain View CA

International Classification:

A61M 1100

US Classification:

12820014, 12820312, 604 48, 604514, 604186, 604246

Abstract:

An apparatus to make a certain volume of liquid available for atomization comprises a container adapted to hold a liquid, and a piston pump. The piston pump comprises a piston member and a valve body, with the piston member being slidable within the valve body. Further, the valve body functions with the piston member to define a metering chamber. In this way, the metering chamber is adapted to be filled with liquid from the container when the piston member is moved to a filling position, and the piston pump is adapted to dispense a known volume of the liquid from the metering chamber when the piston member is moved to a dispensing position.

US Patent:

7174888, Feb 13, 2007

Filed:

Sep 5, 2003

Appl. No.:

10/655642

Inventors:

Yehuda Ivri - Irvine CA, US
Cheng Wu - Sunnyvale CA, US

Assignee:

Aerogen, Inc. - San Carlos CA

International Classification:

A61M 16/00

US Classification:

12820016, 12820312

Abstract:

The invention provides methods and apparatus for nebulizing liquids. In one exemplary embodiment, an apparatus is provided which comprises a thin shell member having a front surface, a rear surface, and a plurality of apertures extending therebetween. The apertures are tapered to narrow from the rear surface to the front surface. A liquid supplier is further provided which delivers a predetermined unit volume of liquid to the rear surface. A vibrator vibrates the thin shell member to eject liquid droplets from the front surface of the thin shell member.

US Patent:

8561604, Oct 22, 2013

Filed:

Feb 12, 2007

Appl. No.:

11/674089

Inventors:

Yehuda Ivri - Irvine CA, US
Cheng H. Wu - Sunnyvale CA, US

Assignee:

Novartis AG - Basel

International Classification:

B05B 17/06

US Classification:

12820016, 12820014, 12820312

Abstract:

The invention provides methods and apparatus for nebulizing liquids. In one exemplary embodiment, an apparatus is provided which comprises a thin shell member having a front surface, a rear surface, and a plurality of apertures extending therebetween. The apertures are tapered to narrow from the rear surface to the front surface. A liquid supplier is further provided which delivers a predetermined unit volume of liquid to the rear surface. A vibrator vibrates the thin shell member to eject liquid droplets from the front surface of the thin shell member.

US Patent:

8578931, Nov 12, 2013

Filed:

Apr 18, 2000

Appl. No.:

09/551408

Inventors:

Yehuda Ivri - Irvine CA, US
Linda R. De Young - El Granada CA, US
Cheng H. Wu - Sunnyvale CA, US
Miro S. Cater - Daytona Beach FL, US
Vijay Kumar - Sunnyvale CA, US
Markus Flierl - Sunnyvale CA, US

Assignee:

Novartis AG - Basel

International Classification:

A61M 15/00
B05B 17/06
B05B 5/00

US Classification:

12820016, 12820014, 12820018, 239696, 604 92

Abstract:

The invention provides exemplary aerosolization apparatus and methods for aerosolizing a substance. According to one exemplary method, a liquid is transferred from a first chamber into a second chamber having a substance that is in a dry state to form a solution. The solution is then transferred from the second chamber and onto an atomization member. The atomization member is operated to aerosolize the solution.

US Patent:

62059998, Mar 27, 2001

Filed:

Sep 8, 1998

Appl. No.:

9/149426

Inventors:

Yehuda Ivri - Irvine CA
Linda R. De Young - El Granda CA
Cheng H. Wu - Sunnyvale CA
Miro S. Cater - Daytona Beach FL
Vijay Kumar - Sunnyvale CA
Markus Flierl - Sunnyvale CA

Assignee:

Aerogen, Inc. - Sunnyvale CA

International Classification:

A61M11/00

US Classification:

12820022

Abstract:

The invention provides exemplary aerosolization apparatus and methods for aerosolizing a substance. According to one exemplary method, a liquid is transferred from a first chamber into a second chamber having a substance that is in a dry state to form a solution. The solution is then transferred from the second chamber and onto an atomization member. The atomization member is operated to aerosolize the solution.