Chengcheng Zhang from Natick, MA, age 40

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Methods For Expansion And Analysis Of Cultured Hematopoietic Stem Cells
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US Patent:

7807464, Oct 5, 2010
Filed:

May 23, 2006
Appl. No.:

11/438847
Inventors:

Chengcheng Zhang - Arlington MA, US
Harvey F. Lodish - Brookline MA, US
Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:

C12N 5/00
US Classification:

435377, 435325, 435375
Abstract:

Methods and kits for propagating hematopoietic stem cells are provided. The methods comprise culturing cells in medium comprising one or more angiopoietin-like proteins, under conditions sufficient for expansion of HSCs. Angiopoietin-like proteins include angiopoietin-like protein 2, angiopoietin-like protein 3, angiopoietin-like protein 4, angiopoietin-like protein 5, angiopoietin-like protein 7, and microfibrillar-associated glycoprotein (Mfap4). Methods for identifying hematopoietic stem cells are provided and isolated hematopoietic stem cells are also provided.

Methods For Expansion And Analysis Of Cultured Hematopoietic Stem Cells
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US Patent:

8506955, Aug 13, 2013
Filed:

Aug 10, 2010
Appl. No.:

12/853677
Inventors:

Chengcheng Zhang - Arlington MA, US
Harvey F. Lodish - Brookline MA, US
Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:

C12N 5/00
US Classification:

424 937, 435325, 435375
Abstract:

Methods and kits for propagating hematopoietic stem cells are provided. The methods comprise culturing cells in medium comprising one or more angiopoietin-like proteins, under conditions sufficient for expansion of HSCs. Angiopoietin-like proteins include angiopoietin-like protein 2, angiopoietin-like protein 3, angiopoietin-like protein 4, angiopoietin-like protein 5, angiopoietin-like protein 7, and microfibrillar-associated glycoprotein (Mfap4). Methods for identifying hematopoietic stem cells are provided and isolated hematopoietic stem cells are also provided.

Cultured Hematopoietic Stem Cells And Method For Expansion And Analysis Thereof
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US Patent:

8617885, Dec 31, 2013
Filed:

Jul 6, 2010
Appl. No.:

12/830709
Inventors:

Chengcheng Zhang - Arlington MA, US
Harvey Lodish - Brookline MA, US
Assignee:

Whitehead Institute for Biomedical Research - Cambridge MA
International Classification:

C12N 5/00
US Classification:

435375, 435325, 435377, 435975
Abstract:

Hematopoietic stem cells and methods for ex vivo expansion of hematopoietic stem cells are provided. The methods comprise culturing the cells in a media containing an effective amount insulin-like growth factor(IGF), fibroblast growth factor (FGF), thrombopoietin (TPO), and stem cell factor (SCF), under conditions sufficient for expansion of said cells. Methods for identifying expanded hematopoeitc stem cells and kits for ex vivo expansion of hematopoietic stem cells are also provided.

Cultured Hematopoietic Stem Cells And Method For Expansion And Analysis Thereof
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US Patent:

20060115898, Jun 1, 2006
Filed:

Oct 20, 2005
Appl. No.:

11/255191
Inventors:

Chengcheng Zhang - Arlington MA, US
Harvey Lodish - Brookline MA, US
International Classification:

C12N 5/08
C12N 5/06
US Classification:

435372000, 435325000
Abstract:

Hematopoietic stem cells and methods for ex vivo expansion of hematopoietic stem cells are provided. The methods comprise culturing the cells in a media containing an effective amount insulin-like growth factor (IGF), fibroblast growth factor (FGF), thrombopoietin (TPO), and stem cell factor (SCF), under conditions sufficient for expansion of said cells. Methods for identifying expanded hematopoeitc stem cells and kits for ex vivo expansion of hematopoietic stem cells are also provided.

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Friends:

Lu Peng, Carol Lei, Simon Shen, Justin Xie, Benson Weng

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Friends:

Jiping Li, Wang Meng, Aronzo Lin, Charles Mui Zi Lek, Desa Palma, Yue Hu

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Reference: Secretogranin 2 binds LILRB4 resulting in immunosuppression by Xing Yang, Ryan Huang, Meng Fang, Yubo He, Jingjing Xie, Xiaoye Liu, Chengcheng Zhang, Qi Lou, Mi Deng, Wei Xiong, Cheryl Lewis, Zade Sadek, Ankit Gupta, Lianqi Chen, Xuewu Zhang, Lei Guo, Lin Xu, Ningyan Zhang, Zhiqiang An
Date: Aug 25, 2025
Category: Health
Source: Google