Cheryl L Wilder

US Patent:

20010021379, Sep 13, 2001

Filed:

Dec 4, 2000

Appl. No.:

09/729402

Inventors:

Lawrence Cousens - Oakland CA, US
Christine Eberhardt - Auburn WA, US
Patrick Gray - Seattle WA, US
Hai Trong - Edmonds WA, US
Larry Tjoelker - Kirkland WA, US
Cheryl Wilder - Seattle WA, US

Assignee:

ICOS Corporation

International Classification:

A61K038/46
C12Q001/68
C12N009/14
C12N015/09
C12N015/70
C12N005/06
C12N015/74
C12N015/63
C12N015/00
C07H021/04

US Classification:

424/094600, 435/320100, 435/195000, 435/338000, 435/007400, 435/006000, 536/023200, 536/024500, 530/388260

Abstract:

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events.

US Patent:

20030072747, Apr 17, 2003

Filed:

Oct 13, 2001

Appl. No.:

10/003978

Inventors:

Lawrence Cousens - Oakland CA, US
Christine Eberhardt - Auburn WA, US
Patrick Gray - Seattle WA, US
Hai Trong - Edmonds WA, US
Larry Tjoelker - Kirkland WA, US
Cheryl Wilder - Seattle WA, US

Assignee:

ICOS Corporation

International Classification:

A61K038/44
A61K038/46

US Classification:

424/094400, 424/094600

Abstract:

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events.

US Patent:

20050100540, May 12, 2005

Filed:

Aug 4, 2003

Appl. No.:

10/633735

Inventors:

Lawrence Cousens - Oakland CA, US
Christine Eberhardt - Auburn WA, US
Patrick Gray - Seattle WA, US
Hai Trong - Edmonds WA, US
Larry Tjoelker - Kirkland WA, US
Cheryl Wilder - Seattle WA, US

International Classification:

A61K038/46
A61K038/48

US Classification:

424094640

Abstract:

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events.

US Patent:

56416695, Jun 24, 1997

Filed:

Oct 6, 1994

Appl. No.:

8/318905

Inventors:

Lawrence S. Cousens - Oakland CA
Christine D. Eberhardt - Auburn WA
Patrick Gray - Seattle WA
Hai Le Trong - Seattle WA
Larry W. Tjoelker - Bothell WA
Cheryl L. Wilder - Bellevue WA

Assignee:

ICOS Corporation - Bothell WA

International Classification:

C12N 914

US Classification:

435195

Abstract:

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events.

US Patent:

55321526, Jul 2, 1996

Filed:

Jun 6, 1995

Appl. No.:

8/470187

Inventors:

Lawrence S. Cousens - Oakland CA
Christine D. Eberhardt - Auburn WA
Patrick Gray - Seattle WA
Larry W. Tjoelker - Bothell WA
Cheryl L. Wilder - Bellevue WA
Hai Trong - Seattle WA

Assignee:

ICOS Corporation - Bothell WA

International Classification:

C12N 918
C12N 1555
C12N 510
C12N 115

US Classification:

435197

Abstract:

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events.

US Patent:

59773081, Nov 2, 1999

Filed:

Aug 12, 1997

Appl. No.:

8/910041

Inventors:

Lawrence S. Cousens - Oakland CA
Christine D. Eberhardt - Redmond WA
Patrick Gray - Seattle WA
Hai Le Trong - Edmonds WA
Larry W. Tjoelker - Kirkland WA
Cheryl L. Wilder - Seattle WA

Assignee:

ICOS Corporation - Bothell WA

International Classification:

C07K 1400
C07K 500
C07H 2104

US Classification:

530350

Abstract:

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events.

US Patent:

61466255, Nov 14, 2000

Filed:

Jan 22, 1998

Appl. No.:

9/010715

Inventors:

Lawrence S. Cousens - Oakland CA
Christine D. Eberhardt - Auburn WA
Patrick Gray - Seattle WA
Hai Le Trong - Edmonds WA
Larry W. Tjoelker - Kirkland WA
Cheryl L. Wilder - Seattle WA

Assignee:

ICOS Corporation - Bothell WA

International Classification:

A61K 3846

US Classification:

424 946

Abstract:

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events.

US Patent:

56058012, Feb 25, 1997

Filed:

Jun 7, 1995

Appl. No.:

8/478465

Inventors:

Lawrence S. Cousens - Oakland CA
Christine D. Eberhardt - Auburn WA
Patrick Gray - Seattle WA
Hai L. Trong - Seattle WA
Larry W. Tjoelker - Bothell WA
Cheryl L. Wilder - Bellevue WA

Assignee:

ICOS Corporation - Bothell WA

International Classification:

C12Q 168

US Classification:

435 6

Abstract:

The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events. Furthermore provided are therapeutic and diagnostic methods using such polynucleotide sequences and platelet-activating factor acethylhydrolase products.