Chia Hung Chu from Winchester, MA, age 41

Compostions And Methods For Nucleic Acid Transfection Using Cationic Polymers And Stabilizers
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US Patent:

20230013253, Jan 19, 2023
Filed:

Dec 16, 2020
Appl. No.:

17/756951
Inventors:

- New York NY, US
Chia Hung Chu - Chesterfield MO, US
International Classification:

C12N 15/86
Abstract:

Provided are compositions and methods for stabilizing a transfection cocktail containing DNA-cationic polymer complexes for an extended time, while maintaining high transfection efficiency. Such stabilized transfection cocktail can be used to generate transfected cells that can produce, for example, rAAV vectors on a large scale without impacting the key attributes of the virus production, such as, titer, DNA packaged rAAV particle fraction, and rAAV vector purification profile.

Sialylated Glycoproteins
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US Patent:

20200087402, Mar 19, 2020
Filed:

Nov 19, 2019
Appl. No.:

16/688772
Inventors:

- Cambridge MA, US
Chia Lin Chu - Somerville MA, US
Laura Rutitzky - Somerville MA, US
Lynn Zhang - Acton MA, US
Leona E. Ling - Winchester MA, US
International Classification:

C07K 16/28
C07K 16/00
Abstract:

Pharmaceutical preparations containing polypeptides having particular sialylation patterns, and methods for the treatment of immune-related thrombocytopenia with such preparations, are described.

Sialylated Glycoproteins
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US Patent:

20180327498, Nov 15, 2018
Filed:

May 21, 2018
Appl. No.:

15/985288
Inventors:

- Cambridge MA, US
Chia Lin Chu - Somerville MA, US
Laura Rutitzky - Somerville MA, US
Lynn Zhang - Acton MA, US
Leona E. Ling - Winchester MA, US
International Classification:

C07K 16/28
C07K 16/00
Abstract:

Pharmaceutical preparations containing polypeptides having particular sialylation patterns, and methods for the treatment of immune-related thrombocytopenia with such preparations, are described.

Sialylated Glycoproteins
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US Patent:

20160257754, Sep 8, 2016
Filed:

Oct 14, 2014
Appl. No.:

15/028917
Inventors:

- Cambridge MA, US
Chia Lin CHU - Somerville MA, US
Laura RUTITZKY - Somerville MA, US
Lynn ZHANG - Acton MA, US
Leona E. LING - Winchester MA, US
Assignee:

Momenta Pharmaceuticals Inc. - Cambridge MA
International Classification:

C07K 16/28
Abstract:

Pharmaceutical preparations containing polypeptides having particular sialylation patterns, and methods for the treatment of immune-related thrombocytopenia with such preparations, are described.